Search Results - "Dieguez, Hernán H."
-
1
An ethologically relevant paradigm to assess defensive response to looming visual contrast stimuli
Published in Scientific reports (31-05-2024)“…In the animal kingdom, threat information is perceived mainly through vision. The subcortical visual pathway plays a critical role in the rapid processing of…”
Get full text
Journal Article -
2
Mitochondrial quality control in non-exudative age-related macular degeneration: From molecular mechanisms to structural and functional recovery
Published in Free radical biology & medicine (01-07-2024)“…Non-exudative age-related macular degeneration (NE-AMD) is the leading blindness cause in the elderly. Clinical and experimental evidence supports that early…”
Get full text
Journal Article -
3
Early life stress induces visual dysfunction and retinal structural alterations in adult mice
Published in Journal of neurochemistry (01-05-2023)“…Early life stress (ELS) is defined as a period of severe and/or chronic trauma, as well as environmental/social deprivation or neglect in the prenatal/early…”
Get full text
Journal Article -
4
Oxidative stress damage circumscribed to the central temporal retinal pigment epithelium in early experimental non-exudative age-related macular degeneration
Published in Free radical biology & medicine (01-02-2019)“…Non-exudative age-related macular degeneration (NE-AMD) represents the leading cause of blindness in the elderly. The macular retinal pigment epithelium (RPE)…”
Get full text
Journal Article -
5
Melatonin protects the retina from experimental nonexudative age‐related macular degeneration in mice
Published in Journal of pineal research (01-05-2020)“…Nonexudative age‐related macular degeneration (NE‐AMD) represents the leading cause of blindness in the elderly. Currently, there are no available treatments…”
Get full text
Journal Article -
6
Enriched environment and visual stimuli protect the retinal pigment epithelium and photoreceptors in a mouse model of non-exudative age-related macular degeneration
Published in Cell death & disease (04-12-2021)“…Non-exudative age-related macular degeneration (NE-AMD), the main cause of blindness in people above 50 years old, lacks effective treatments at the moment. We…”
Get full text
Journal Article -
7
Melatonin Prevents Non-image-Forming Visual System Alterations Induced by Experimental Glaucoma in Rats
Published in Molecular neurobiology (01-08-2021)“…Glaucoma is a blindness-causing disease that involves selective damage to retinal ganglion cells (RGCs) and their axons. A subset of RGCs expressing the…”
Get full text
Journal Article -
8
Therapeutic benefit of environmental enrichment on optic neuritis
Published in Neuropharmacology (01-02-2019)“…Optic neuritis (ON) is an inflammatory, demyelinating, neurodegenerative, and presently untreatable condition of the optic nerve which might induce blindness…”
Get full text
Journal Article -
9
The “Use It or Lose It” Dogma in the Retina: Visual Stimulation Promotes Protection Against Retinal Ischemia
Published in Molecular neurobiology (2020)“…Enriched environment (EE) protects the retina from adult rats against ischemia/reperfusion (I/R) injury; however, how the components of EE contribute to the…”
Get full text
Journal Article -
10
Superior cervical gangliectomy induces non-exudative age-related macular degeneration in mice
Published in Disease models & mechanisms (01-02-2018)“…Non-exudative age-related macular degeneration, a prevalent cause of blindness, is a progressive and degenerative disease characterized by alterations in…”
Get full text
Journal Article -
11
Pre-ischemic enriched environment increases retinal resilience to acute ischemic damage in adult rats
Published in Experimental eye research (01-01-2019)“…Retinal ischemia is a condition associated with several degenerative diseases leading to visual impairment and blindness worldwide. Currently, there is no…”
Get full text
Journal Article -
12
Critical Role of Monocyte Recruitment in Optic Nerve Damage Induced by Experimental Optic Neuritis
Published in Molecular neurobiology (01-11-2019)“…Neuroinflammatory diseases are characterized by blood-brain barrier disruption (BBB) and leukocyte infiltration. We investigated the involvement of monocyte…”
Get full text
Journal Article