Search Results - "Diebold, S S"

Recognition of viral single-stranded RNA by Toll-like receptors by Diebold, Sandra S.

“…The Toll-like receptors (TLR), mediating innate immune activation upon recognition of viral nucleic acids, represent promising targets for the development of…”
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Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA by Diebold, Sandra S., Kaisho, Tsuneyasu, Hemmi, Hiroaki, Akira, Shizuo, Caetano Reis e Sousa

“…Interferons (IFNs) are critical for protection from viral infection, but the pathways linking virus recognition to IFN induction remain poorly understood…”
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Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis by Muliaditan, Tamara, Caron, Jonathan, Okesola, Mary, Opzoomer, James W., Kosti, Paris, Georgouli, Mirella, Gordon, Peter, Lall, Sharanpreet, Kuzeva, Desislava M., Pedro, Luisa, Shields, Jacqueline D., Gillett, Cheryl E., Diebold, Sandra S., Sanz-Moreno, Victoria, Ng, Tony, Hoste, Esther, Arnold, James N.

“…Tumour-associated macrophages (TAMs) play an important role in tumour progression, which is facilitated by their ability to respond to environmental cues. Here…”
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Toll-like receptor 3 promotes cross-priming to virus-infected cells by Reis e Sousa, Caetano, Schulz, Oliver, Diebold, Sandra S, Chen, Margaret, Näslund, Tanja I, Nolte, Martijn A, Alexopoulou, Lena, Azuma, Yasu-Taka, Flavell, Richard A, Liljeström, Peter

“…Cross-presentation of cell-associated antigens plays an important role in regulating CD8+ T cell responses to proteins that are not expressed by…”
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Antibody conjugates for targeted delivery of Toll-like receptor 9 agonist to the tumor tissue by Corogeanu, Diana, Zaki, Kam, Beavil, Andrew J, Arnold, James N, Diebold, Sandra S

“…Imiquimod, a Toll-like receptor 7 (TLR7) agonist is routinely used for topical administration in basal cell carcinoma and stage zero melanoma. Similarly, the…”
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Design and performance simulation studies of a breast PET insert integrable into a clinical whole-body PET/MRI scanner by Pommranz, C M, Schmidt, F P, Mannheim, J G, Diebold, S J, Tenzer, C, Santangelo, A, Pichler, B J

“… Three different breast positron emission tomography (PET) insert geometries are proposed for integration into an existing magnetic resonance imaging (MRI)…”
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Viral infection switches non-plasmacytoid dendritic cells into high interferon producers by Sousa, Caetano Reis e, Diebold, Sandra S, Montoya, Maria, Unger, Hermann, Alexopoulou, Lena, Roy, Polly, Haswell, Linsey E, Al-Shamkhani, Aymen, Flavell, Richard, Borrow, Persephone

“…Type I interferons (IFN-I) are important cytokines linking innate and adaptive immunity. Plasmacytoid dendritic cells make high levels of IFN-I in response to…”
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Nucleic acid agonists for Toll‐like receptor 7 are defined by the presence of uridine ribonucleotides by Diebold, Sandra S., Massacrier, Catherine, Akira, Shizuo, Paturel, Carine, Morel, Yannis, Reis e Sousa, Caetano

“…Toll‐like receptor 7 (TLR7) mediates innate responses by responding to viral RNA in endocytic compartments. However, the molecular pattern recognised by TLR7…”
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Nucleic acids and endosomal pattern recognition: how to tell friend from foe? by Brencicova, Eva, Diebold, Sandra S

“…The innate immune system has evolved endosomal and cytoplasmic receptors for the detection of viral nucleic acids as sensors for virus infection. Some of these…”
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Plant virus particles carrying tumour antigen activate TLR7 and Induce high levels of protective antibody by Jobsri, Jantipa, Allen, Alex, Rajagopal, Deepa, Shipton, Michael, Kanyuka, Kostya, Lomonossoff, George P, Ottensmeier, Christian, Diebold, Sandra S, Stevenson, Freda K, Savelyeva, Natalia

“…Induction of potent antibody is the goal of many vaccines targeted against infections or cancer. Modern vaccine designs that use virus-like particles (VLP)…”
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Plasmacytoid dendritic cell–derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists by Rajagopal, Deepa, Paturel, Carine, Morel, Yannis, Uematsu, Satoshi, Akira, Shizuo, Diebold, Sandra S.

“…There is a high demand for the development of adjuvants that induce cytotoxic T lymphocytes, which are crucial for the elimination of intracellular pathogens…”
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Activation of dendritic cells by toll-like receptors and C-type lectins by Diebold, Sandra S

“…As sentinels of the immune system, dendritic cells (DC) scan their environment for the presence of pathogens. DC sense pathogens either directly or indirectly…”
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Myosin II Synergizes with F-Actin to Promote DNGR-1-Dependent Cross-Presentation of Dead Cell-Associated Antigens by Schulz, Oliver, Hanč, Pavel, Böttcher, Jan P., Hoogeboom, Robbert, Diebold, Sandra S., Tolar, Pavel, Reis e Sousa, Caetano

“…Conventional type 1 DCs (cDC1s) excel at cross-presentation of dead cell-associated antigens partly because they express DNGR-1, a receptor that recognizes…”
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Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma by Brencicova, Eva, Jagger, Ann L, Evans, Hayley G, Georgouli, Mirella, Laios, Alex, Attard Montalto, Steve, Mehra, Gautam, Spencer, Jo, Ahmed, Ahmed A, Raju-Kankipati, Shanti, Taams, Leonie S, Diebold, Sandra S

“…Dendritic cells (DC) have the potential to instigate a tumour-specific immune response, but their ability to prime naïve lymphocytes depends on their…”
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Antibody-mediated depletion of immunosuppressive factors from ovarian carcinoma-associated ascites for investigation of paracrine versus autocrine effects by Brencicova, E., Diebold, S.S.

“…Many studies seek to explore the impact of extrinsic soluble factors present in serum, interstitial fluids or cell-conditioned media on cells in vitro. A…”
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Making EBSD on water ice routine by PRIOR, D.J., LILLY, K., SEIDEMANN, M., VAUGHAN, M., BECROFT, L., EASINGWOOD, R., DIEBOLD, S., OBBARD, R., DAGHLIAN, C., BAKER, I., CASWELL, T., GOLDING, N., GOLDSBY, D., DURHAM, W.B., PIAZOLO, S., WILSON, C.J.L.

“…Summary Electron backscatter diffraction (EBSD) on ice is a decade old. We have built upon previous work to select and develop methods of sample preparation…”
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Network-driven discovery yields new insight into Shox2-dependent cardiac rhythm control by Hoffmann, S., Schmitteckert, S., Raedecke, K., Rheinert, D., Diebold, S., Roeth, R., Weiss, B., Granzow, M., Niesler, B., Griesbeck, A., Eckstein, V., Zimmermann, W.-H., Just, S., Rappold, G.A.

“…The homeodomain transcription factor SHOX2 is involved in the development and function of the heart's primary pacemaker, the sinoatrial node (SAN), and has…”
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Glucose-dependent insulinotropic peptide secretion is induced by inflammatory stimuli in an interleukin-1-dependent manner in mice by Kahles, F., Meyer, C., Diebold, S., Foldenauer, A. C., Stöhr, R., Möllmann, J., Lebherz, C., Findeisen, H. M., Marx, N., Lehrke, M.

“…Recently, glucagon‐like peptide‐1 (GLP‐1) levels have been found to be increased in response to inflammatory stimuli, leading to insulin secretion and…”
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Microbial Recognition Via Toll-Like Receptor-Dependent and -Independent Pathways Determines the Cytokine Response of Murine Dendritic Cell Subsets to CD40 Triggering by Edwards, Alexander D, Manickasingham, Shivanthi P, Sporri, Roman, Diebold, Sandra S, Schulz, Oliver, Sher, Alan, Kaisho, Tsuneyasu, Akira, Shizuo, Reis e Sousa, Caetano

“…Dendritic cells (DC) can produce Th-polarizing cytokines and direct the class of the adaptive immune response. Microbial stimuli, cytokines, chemokines, and T…”
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Toll‐like receptor expression in murine DC subsets: lack of TLR7 expression by CD8α+ DC correlates with unresponsiveness to imidazoquinolines by Edwards, Alexander D., Diebold, Sandra S., Slack, Emma M. C., Tomizawa, Hideyuki, Hemmi, Hiroaki, Kaisho, Tsuneyasu, Akira, Shizuo, Sousa, Caetano Reis e

“…Toll‐like receptors (TLR) recognize microbial and viral patterns and activate dendritic cells (DC). TLR distribution among human DC subsets is heterogeneous:…”
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