Search Results - "Dickmeis, Thomas"
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Glucocorticoids and the circadian clock
Published in Journal of endocrinology (01-01-2009)“…Glucocorticoids, hormones produced by the adrenal gland cortex, perform numerous functions in body homeostasis and the response of the organism to external…”
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The circadian clock and glucocorticoids – Interactions across many time scales
Published in Molecular and cellular endocrinology (05-11-2013)“…•The circadian clock regulates endogenous daily rhythms in physiology.•Glucocorticoid (GC) signaling is highly dynamic on time scales from seconds to…”
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Pax6 organizes the anterior eye segment by guiding two distinct neural crest waves
Published in PLoS genetics (17-06-2020)“…Cranial neural crest (NC) contributes to the developing vertebrate eye. By multidimensional, quantitative imaging, we traced the origin of the ocular NC cells…”
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Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids
Published in PLoS genetics (01-12-2016)“…Altered daily patterns of hormone action are suspected to contribute to metabolic disease. It is poorly understood how the adrenal glucocorticoid hormones…”
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5
Glycolysis supports embryonic muscle growth by promoting myoblast fusion
Published in Proceedings of the National Academy of Sciences - PNAS (19-11-2013)“…Muscles ensure locomotion behavior of invertebrate and vertebrate organisms. They are highly specialized and form using conserved developmental programs. To…”
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The light responsive transcriptome of the zebrafish: function and regulation
Published in PloS one (15-02-2011)“…Most organisms possess circadian clocks that are able to anticipate the day/night cycle and are reset or "entrained" by the ambient light. In the zebrafish,…”
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Molecular description of eye defects in the zebrafish Pax6b mutant, sunrise, reveals a Pax6b-dependent genetic network in the developing anterior chamber
Published in PloS one (18-02-2015)“…The cornea is a central component of the camera eye of vertebrates and even slight corneal disturbances severely affect vision. The transcription factor PAX6…”
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Development of a Benzophenone-Free Red Propolis Extract and Evaluation of Its Efficacy against Colon Carcinogenesis
Published in Pharmaceuticals (Basel, Switzerland) (08-10-2024)“…Brazilian red propolis has attracted attention for its pharmacological properties. However, signs of toxicity were recently observed in long-term studies using…”
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Real-time in vivo monitoring of circadian E-box enhancer activity: A robust and sensitive zebrafish reporter line for developmental, chemical and neural biology of the circadian clock
Published in Developmental biology (15-08-2013)“…The circadian clock co-ordinates physiology and behavior with the day/night cycle. It consists of a transcriptional–translational feedback loop that generates…”
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MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly
Published in eLife (24-09-2020)“…The glucose-sensing Mondo pathway regulates expression of metabolic genes in mammals. Here, we characterized its function in the zebrafish and revealed an…”
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Glucocorticoids play a key role in circadian cell cycle rhythms
Published in PLoS biology (01-04-2007)“…Clock output pathways play a pivotal role by relaying timing information from the circadian clock to a diversity of physiological systems. Both cell-autonomous…”
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Automated processing of zebrafish imaging data: a survey
Published in Zebrafish (01-09-2013)“…Due to the relative transparency of its embryos and larvae, the zebrafish is an ideal model organism for bioimaging approaches in vertebrates. Novel microscope…”
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Nano-Sampling and Reporter Tools to Study Metabolic Regulation in Zebrafish
Published in Frontiers in cell and developmental biology (19-02-2019)“…In the past years, evidence has emerged that hallmarks of human metabolic disorders can be recapitulated in zebrafish using genetic, pharmacological or dietary…”
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Start the clock! Circadian rhythms and development
Published in Developmental dynamics (01-01-2007)“…The contribution of timing cues from the environment to the coordination of early developmental processes is poorly understood. The day–night cycle represents…”
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A crucial component of the endoderm formation pathway, CASANOVA, is encoded by a novel sox-related gene
Published in Genes & development (15-06-2001)“…casanova (cas) mutant zebrafish embryos lack endoderm and develop cardia bifida. In a substractive screen for Nodal-responsive genes, we isolated an HMG…”
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Nodal and Fgf pathways interact through a positive regulatory loop and synergize to maintain mesodermal cell populations
Published in Development (Cambridge) (01-02-2004)“…Interactions between Nodal/Activin and Fibroblast growth factor (Fgf) signalling pathways have long been thought to play an important role in mesoderm…”
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Rasl11b knock down in zebrafish suppresses one-eyed-pinhead mutant phenotype
Published in PloS one (16-01-2008)“…The EGF-CFC factor Oep/Cripto1/Frl1 has been implicated in embryogenesis and several human cancers. During vertebrate development, Oep/Cripto1/Frl1 has been…”
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Molecular integration of casanova in the Nodal signalling pathway controlling endoderm formation
Published in Development (Cambridge) (01-01-2002)“…Endoderm originates from a large endomesodermal field requiring Nodal signalling. The mechanisms that ensure segregation of endoderm from mesoderm are not…”
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Stem cells and the circadian clock
Published in Developmental biology (15-11-2017)“…The circadian timing system is a complex biological network of interacting circadian clocks that regulates 24h rhythms of behavioral and physiological…”
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Archiving of zebrafish lines can reduce animal experiments in biomedical research
Published in EMBO reports (01-01-2017)“…Graphical Abstract As zebrafish become an increasingly popular model organism in biomedical research, lines of genetically modified fish are a valuable…”
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