Search Results - "Dickler, Howard B"

Global analyses of human immune variation reveal baseline predictors of postvaccination responses by Tsang, John S, Schwartzberg, Pamela L, Kotliarov, Yuri, Biancotto, Angelique, Xie, Zhi, Germain, Ronald N, Wang, Ena, Olnes, Matthew J, Narayanan, Manikandan, Golding, Hana, Moir, Susan, Dickler, Howard B, Perl, Shira, Cheung, Foo

“…A major goal of systems biology is the development of models that accurately predict responses to perturbation. Constructing such models requires the…”
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Promoting translational and clinical science: the critical role of medical schools and teaching hospitals by Dickler, Howard B, Korn, David, Gabbe, Steven G

“…Academic translational and clinical research in the US faces serious obstacles. Dickler and colleagues outline the Association of American Medical Colleges…”
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Effects of Systemically Administered Hydrocortisone on the Human Immunome by Olnes, Matthew J., Kotliarov, Yuri, Biancotto, Angélique, Cheung, Foo, Chen, Jinguo, Shi, Rongye, Zhou, Huizhi, Wang, Ena, Tsang, John S., Nussenblatt, Robert

“…Corticosteroids have been used for decades to modulate inflammation therapeutically, yet there is a paucity of data on their effects in humans. We examined the…”
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Acute and persistent responses after H5N1 vaccination in humans by Apps, Richard, Biancotto, Angélique, Candia, Julián, Kotliarov, Yuri, Perl, Shira, Cheung, Foo, Farmer, Rohit, Mulè, Matthew P., Rachmaninoff, Nicholas, Chen, Jinguo, Martins, Andrew J., Shi, Rongye, Zhou, Huizhi, Bansal, Neha, Schum, Paula, Olnes, Matthew J., Milanez-Almeida, Pedro, Han, Kyu Lee, Sellers, Brian, Cortese, Mario, Hagan, Thomas, Rouphael, Nadine, Pulendran, Bali, King, Lisa, Manischewitz, Jody, Khurana, Surender, Golding, Hana, van der Most, Robbert G., Dickler, Howard B., Germain, Ronald N., Schwartzberg, Pamela L., Tsang, John S.

“…To gain insight into how an adjuvant impacts vaccination responses, we use systems immunology to study human H5N1 influenza vaccination with or without the…”
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New Physician-Investigators Receiving National Institutes of Health Research Project Grants: A Historical Perspective on the “Endangered Species” by Dickler, Howard B, Fang, Di, Heinig, Stephen J, Johnson, Elizabeth, Korn, David

“…CONTEXT Although concerns have persisted for decades about the production of new physician clinical scientists and their success in receiving and sustaining…”
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Sustaining the Engine of U.S. Biomedical Discovery by Heinig, Stephen J, Krakower, Jack Y, Dickler, Howard B, Korn, David

“…Academic medical centers are where most of the research sponsored by the National Institutes of Health (NIH) is performed. In the past decade, the centers have…”
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The National Institutes of Health Center for Human Immunology, Autoimmunity, and Inflammation: history and progress by Dickler, Howard B., McCoy, J. Philip, Nussenblatt, Robert, Perl, Shira, Schwartzberg, Pamela A., Tsang, John S., Wang, Ena, Young, Neil S.

“…The Center for Human Immunology, Autoimmunity, and Inflammation (CHI) is an exciting initiative of the NIH intramural program begun in 2009. It is uniquely…”
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Correction: Corrigendum: Effects of Systemically Administered Hydrocortisone on the Human Immunome by Olnes, Matthew J., Kotliarov, Yuri, Biancotto, Angélique, Cheung, Foo, Chen, Jinguo, Shi, Rongye, Zhou, Huizhi, Wang, Ena, Tsang, John S., Nussenblatt, Robert

“…Scientific Reports 6: Article number: 23002; published online: 14 March 2016; updated: 04 May 2016 This Article contains errors in the Author Contributions…”
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Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses by Tsang, John S., Schwartzberg, Pamela L., Kotliarov, Yuri, Biancotto, Angelique, Xie, Zhi, Germain, Ronald N., Wang, Ena, Olnes, Matthew J., Narayanan, Manikandan, Golding, Hana, Moir, Susan, Dickler, Howard B., Perl, Shira, Cheung, Foo, Obermoser, Gerlinde, Chaussabel, Damien, Palucka, Karolina, Chen, Jinguo, Fuchs, J. Christopher, Ho, Jason, Khurana, Surender, King, Lisa R., Langweiler, Marc, Liu, Hui, Manischewitz, Jody, Pos, Zoltan, Posada, Jacqueline G., Schum, Paula, Shi, Rongye, Valdez, Janet, Wang, Wei, Zhou, Huizhi, Kastner, Daniel L., Marincola, Francesco M., McCoy, J. Philip, Trinchieri, Giorgio, Young, Neal S.

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Identification of an Alternative CTLA-4 Ligand Costimulatory for T Cell Activation by Hathcock, Karen S., Laszlo, Gloria, Dickler, Howard B., Bradshaw, Jeff, Linsley, Peter, Hodes, Richard J.

“…Stimulation of T cell proliferation generally requires two signals: The first signal is provided by the T cell receptor binding to antigen, and the second…”
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The Costs of Institutional Review Boards by Dickler, Howard B, Korn, David

“…To the Editor: The data that Sugarman et al. (April 28 issue) 1 collected in 2002 seriously underestimate the current costs of human-research oversight. Since…”
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Impaired Response to Influenza Vaccination in AML Patients Post-Chemotherapy Associated with a Highly Atypical B-Cell Profile by Goswami, Meghali, Prince, Gabrielle T., Biancotto, Angelique, Moir, Susan, Cheung, Foo, Kotliarov, Yuri, Dunham, Kimberly, Chen, Jinguo, Shi, Rongye, Zhou, Huizhi, Golding, Hana, Tang, Jingrong, Tsang, John S., Dickler, Howard B., Noonan, Kimberly, Smith, B. Douglas, Borrello, Ivan M., Hourigan, Christopher S.

“…The immunotherapy of cancer is arguably the most promising therapy under development, and vaccination against cancer antigens is a promising strategy to…”
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Studies of the human lymphocyte receptor for heat-aggregated or antigen-complexed immunoglobulin by Dickler, H B

“…The lymphocyte receptor for complexed immunoglobulin was shown not to bind heat-aggregated human serum albumin, bovine serum albumin, transferrin, F(ab')(2),…”
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Immunosuppression in the treatment of disease by Dickler, Howard B., Albright, Joseph F.

“…Suppression or modulation of the immune system is increasingly used as a therapeutic modality in disease that span the medical spectrum. The American Academy…”
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Global analyses of human immune variation reveal baseline predictors of post-vaccination responses by Tsang, John S., Schwartzberg, Pamela L., Kotliarov, Yuri, Biancotto, Angelique, Xie, Zhi, Germain, Ronald N., Wang, Ena, Olnes, Matthew J., Narayanan, Manikandan, Golding, Hana, Moir, Susan, Dickler, Howard B., Perl, Shira, Cheung, Foo

“…A major goal of systems biology is the development of models that accurately predict responses to perturbation. Constructing such models requires collection of…”
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The Costs of Institutional Review Boards/THE AUTHORS REPLY by Dickler, Howard B, Korn, David, Bhat, Suneel, Hegde, Timmanna T

“…THE AUTHORS REPLY: Determining the true costs of operating IRBs is a critical first step in identifying ways of reimbursing academic medical centers for this…”
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A Subpopulation of Adherent Accessory Cells Bearing Both I-A and I-E or C Subregion Antigens Is Required for Antigen-Specific Murine T Lymphocyte Proliferation by Cowing, Carol, Pincus, Seth H, Sachs, David H, Dickler, Howard B

“…A murine T lymphocyte proliferation assay that used antigen-primed lymph node T cells, was antigen specific, and required exogenous accessory cells was used to…”
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Macrophage Ia Antigens by Cowing, Carol, Schwartz, Benjamin D., Dickler, Howard B.

“…Abstract By indirect immunofluorescence and microcytotoxicity it was demonstrated that different populations of murine macrophages bear different amounts of Ia…”
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Monoclonal anti-Fc IgG receptor antibodies trigger B lymphocyte function by Lamers, Marinus C, Heckford, Susan E, Dickler, Howard B

“…Despite intensive investigation, it remains unclear which receptor(s) on the B lymphocyte receives the signal(s) which leads to differentiation and antibody…”
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Ir Gene Regulation of Accessory Cell Function by Singer, Alfred, Cowing, Carol C, Dickler, Howard B, Hodes, Richard J

“…Abstract The possibility was investigated that Ir genes regulate the function of cells other than T or B cells in the primary IgM PFC responses to the…”
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