Search Results - "Dickerson, W. Matthew"

Development of a Generic Anti-PEG Antibody Assay Using BioScale’s Acoustic Membrane MicroParticle Technology by Dong, Huijin, Mora, Johanna R., Brockus, Catherine, Chilewski, Shannon D., Dodge, Robert, Merrifield, Colin, Dickerson, W. Matthew, DeSilva, Binodh

“…Immunogenicity testing for PEGylated biotherapeutics should include methods to detect both anti-protein and anti-PEG antibodies (anti-PEG). Although some…”
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Measurement of downstream kinase activity modulation as indicator of epidermal growth factor receptor inhibitor efficacy by Dickerson, W. Matthew, Saab, Ashley, Leong, Kristen, Miller, Michael, Latterich, Martin, Beausang, Lee Anne, Alderman, Edward M.

“…The acoustic membrane micro particle (AMMP) technology has been used to quantify single analytes out of multiple sample types. In this study the technology is…”
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Mechanisms of action of an investigational new freeze-dried platelet-derived hemostatic product by Kuhn, Benjamin J., Swanson, Ana, Cherupalla, Arjun S., Booth, Lisa, Dickerson, W. Matthew, Fitzpatrick, G. Michael, Alexander, W. Allan, Moskowitz, Keith A.

“…A safe and efficacious hemostatic product with a long shelf-life is needed to reduce mortality from hemorrhage due to trauma and improve surgical outcomes for…”
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Evaluation of Acoustic Membrane Microparticle (AMMP) Technology for a Sensitive Ligand Binding Assay to Support Pharmacokinetic Determinations of a Biotherapeutic by Chilewski, Shannon D., Dickerson, W. Matthew, Mora, Johanna R., Saab, Ashley, Alderman, Edward M.

“…Achieving the required sensitivity can be a challenge in the development of ligand binding assays for pharmacokinetic (PK) determinations of biotherapeutics…”
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Abstract 5527: A panel of in vitro kinase assays developed using a novel detection technology to predict and monitor EGFR inhibitor efficacy by Dickerson, W. Matthew, Beausang, Lee Anne, Saab, Ashley, Leong, Kristen, Alderman, Edward

“…The efficacy of kinase inhibitors, a highly studied class of drugs used to treat many forms of cancer, remains difficult to predict or tailor to individual…”
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Abstract 5170: Novel discovery of P38 activation: Expression in A431 cells in in vitro and in vivo models of cancer, measured by a novel assay for p-P38 by Beausang, Lee Anne, Leong, Kristen, Dickerson, W. Matthew, Saab, Ashley, Alderman, Edward M.

“…The p38 enzyme, also known as mitogen activated protein kinase or MAPK (pT180/pY182), is responsive to cellular stress such as osmotic shock, heat shock, and…”
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Abstract 3208: Development of applications for acoustic membrane microparticle assay technology for translational medicine by McAndrew, Christopher, Heger, Christopher, Saab, Ashley, Dickerson, W Matthew, Goldsmith, Paul K.

“…The detection and study of proteins and their interactions utilizing small samples of cells or tissues is an ongoing problem in cancer research. Recent…”
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Abstract 234: Snapshot of MAP kinase and related signal transduction pathways from biopsied cells using a novel non-optical assay technology - a proof of concept study by Dickerson, W. Matthew, Alderman, Edward M., Beausang, Lee Ann, Leong, Kristen, Saab, Ashley

“…Aberrant activity of the MAP and PI3 kinases is implicated in many forms of cancer. The ability to gather quantifiable information on the activation-state of…”
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Extracellular Matrix-derived Peptide Binds to αvβ3 Integrin and Inhibits Angiogenesis by Yohei Maeshima, Udaya L. Yerramalla, Mohanraj Dhanabal, Kathryn A. Holthaus, Sergei Barbashov, Surender Kharbanda, Corinne Reimer, Mark Manfredi, W. Matthew Dickerson, Raghu Kalluri

“…Angiogenesis is associated with several pathological disorders as well as with normal physiological maintenance. Components of vascular basement membrane are…”
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Extracellular Matrix-derived Peptide Binds to αvβ3 Integrin and Inhibits Angiogenesis by Maeshima, Yohei, Yerramalla, Udaya L., Dhanabal, Mohanraj, Holthaus, Kathryn A., Barbashov, Sergei, Kharbanda, Surender, Reimer, Corinne, Manfredi, Mark, Dickerson, W. Matthew, Kalluri, Raghu

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PHARMACOKINETICS OF IV ADMINISTERED MURINE ANTI-HUMAN B7.1 AND MURINE ANTI-HUMAN B7.2 IN CYNOMOLGUS MONKEYS by Damico, Lisa A., Szklut, Pamela, Dickerson, Matthew W., Stone, Joel, Resmini, Christine, Celniker, Abbie C.

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PHARMACOKINETICS OF IV ADMINISTERED MURINE ANTI-HUMAN B7.1 AND MURINE ANTI-HUMAN B7.2 IN CYNOMOLGUS MONKEYS by Damico, Lisa A., Szklut, Pamela, Dickerson, W. Matthew, Stone, Joel, Resmini, Christine, Celniker, Abbie C.

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