Search Results - "Dicker, Anthony J."
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Alterations in gene expression and activity during squamous cell carcinoma development
Published in Cancer research (Chicago, Ill.) (01-07-2002)“…This study focuses on characterizing the genetic and biological alterations associated with squamous cell carcinoma development. Normal human epidermal…”
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Journal Article -
2
E2F-1 induces proliferation-specific genes and suppresses squamous differentiation-specific genes in human epidermal keratinocytes
Published in Oncogene (08-06-2000)“…Squamous differentiation of keratinocytes is associated with decreases in E2F-1 mRNA expression and E2F activity, and these processes are disrupted in squamous…”
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Journal Article -
3
E2F as a Regulator of Keratinocyte Proliferation: Implications for Skin Tumor Development
Published in Journal of investigative dermatology (01-08-1997)“…E2F and DP family members are established regulators of the cell cycle. In this study, we examined their activity/expression during keratinocyte growth arrest…”
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Journal Article Conference Proceeding -
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Isolation (From a Basal Cell Carcinoma) of a Functionally Distinct Fibroblast-Like Cell Type that Overexpresses Ptch
Published in Journal of investigative dermatology (01-05-2002)“…In this study we report on the isolation and characterization of a nonepithelial, nontumorigenic cell type (BCC1) derived from a basal cell carcinoma from a…”
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Journal Article -
5
E2F1 messenger RNA is destabilized in response to a growth inhibitor in normal human keratinocytes but not in a squamous carcinoma cell line
Published in Cancer research (Chicago, Ill.) (15-04-1998)“…Keratinocyte growth arrest is characterized by a reduction in the activity and expression of E2F1. Here, we examine the role posttranscriptional processing…”
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Journal Article -
6
Marking a surgical margin for excision of a keratinocyte cancer
Published in Australian family physician (01-06-2021)“…Cancer Council Australia's clinical guidelines suggest 2-3 mm surgical margins for low-risk tumours and margins >5 mm for high-risk tumours.1 Most research has…”
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Journal Article -
7
Keratinocyte growth arrest is associated with activation of a transcriptional repressor element in the human cdk1 promoter
Published in Journal of cellular physiology (01-12-1998)“…In this study we examined the regulation of cdk1 expression in normal human epidermal keratinocytes (HEKs) and neoplastic keratinocytes. Keratinocytes were…”
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Journal Article -
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Functional Characterization of Cultured Cells Derived from an Intraepidermal Carcinoma of the Skin (IEC-1)
Published in Experimental cell research (01-08-2000)“…We have successfully isolated a cell line (IEC-1) from an intraepidermal carcinoma of the skin of a patient and compared its behavior, in vitro, to normal…”
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Journal Article