Search Results - "Dick, Emily"

Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation by MATSA, Elena, RAJAMOHAN, Divya, DICK, Emily, YOUNG, Lorraine, MELLOR, Ian, STANIFORTH, Andrew, DENNING, Chris

“…Congenital long QT syndromes (LQTSs) are associated with prolonged ventricular repolarization and sudden cardiac death. Limitations to existing clinical…”
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Multi-phosphine-chelated iron-carbide clusters via redox-promoted ligand exchange on an inert hexa-iron-carbide carbonyl cluster, [Fe 6 (μ 6 -C)(μ 2 -CO) 4 (CO) 12 ] 2 by Cobb, Caitlyn R, Ngo, Ren K, Dick, Emily J, Lynch, Vincent M, Rose, Michael J

“…We report the reactivity, structures and spectroscopic characterization of reactions of phosphine-based ligands (mono-, di- and tri-dentate) with iron-carbide…”
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Evaluating the utility of cardiomyocytes from human pluripotent stem cells for drug screening by Dick, Emily, Rajamohan, Divya, Ronksley, Jonathon, Denning, Chris

“…Functional cardiomyocytes can now be derived routinely from hPSCs (human pluripotent stem cells), which collectively include embryonic and induced pluripotent…”
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Identification and Characterization of MEDI4736, an Antagonistic Anti-PD-L1 Monoclonal Antibody by Stewart, Ross, Morrow, Michelle, Hammond, Scott A, Mulgrew, Kathy, Marcus, Danielle, Poon, Edmund, Watkins, Amanda, Mullins, Stefanie, Chodorge, Matthieu, Andrews, John, Bannister, David, Dick, Emily, Crawford, Nicola, Parmentier, Julie, Alimzhanov, Marat, Babcook, John S, Foltz, Ian N, Buchanan, Andrew, Bedian, Vahe, Wilkinson, Robert W, McCourt, Matthew

“…Programmed cell-death 1 ligand 1 (PD-L1) is a member of the B7/CD28 family of proteins that control T-cell activation. Many tumors can upregulate expression of…”
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Family studies of warts, hypogammaglobulinemia, immunodeficiency, myelokathexis syndrome by Dale, David C., Dick, Emily, Kelley, Merideth, Makaryan, Vahagn, Connelly, Jim, Bolyard, Audrey Anna

“…PURPOSE OF REVIEWWHIM syndrome (warts, hypogammaglobulinemia, immunodeficiency, myelokathexis, or WHIMs) is a very rare autosomal dominant immunodeficiency…”
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Exon skipping and gene transfer restore dystrophin expression in human induced pluripotent stem cells-cardiomyocytes harboring DMD mutations by Dick, Emily, Kalra, Spandan, Anderson, David, George, Vinoj, Ritso, Morten, Laval, Steven H, Barresi, Rita, Aartsma-Rus, Annemieke, Lochmüller, Hanns, Denning, Chris

“…With an incidence of ∼1:3,500 to 5,000 in male children, Duchenne muscular dystrophy (DMD) is an X-linked disorder in which progressive muscle degeneration…”
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Role of Interleukin-1 and MyD88-Dependent Signaling in Rhinovirus Infection by STOKES, Clare A, ISMAIL, Saila, DICK, Emily P, BENNETT, Julie A, JOHNSTON, Sebastian L, EDWARDS, Michael R, SABROE, Ian, PARKER, Lisa C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Faster generation of hiPSCs by coupling high-titer lentivirus and column-based positive selection by Dick, Emily, Matsa, Elena, Young, Lorraine E, Darling, David, Denning, Chris

“…The protocols described here address methods used in two crucial stages in the retroviral reprogramming of somatic cells to produce human induced pluripotent…”
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Pathways regulating lipopolysaccharide-induced neutrophil survival revealed by lentiviral transduction of primary human neutrophils by Dick, Emily P, Prince, Lynne R, Prestwich, Elizabeth C, Renshaw, Stephen A, Whyte, Moira K.B, Sabroe, Ian

“…Human neutrophils express Toll-like receptor 4 (TLR4) at low levels, and the role of this receptor in neutrophil responses to microbial stimuli has been…”
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Ex Vivo‐Expanded Bone Marrow CD34+ Derived Neutrophils Have Limited Bactericidal Ability by Dick, Emily Patricia, Prince, Lynne Rebecca, Sabroe, Ian

“…Neutropenia as a consequence of bone marrow failure, severe infections, or intensive chemotherapy is frequently associated with life‐threatening sepsis. Ex…”
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Fiction or reality? Hotel leaders’ perception on climate action and sustainable business models by Dick-Forde, Emily Gaynor, Oftedal, Elin Merethe, Bertella, Giovanna Merethe

“…Purpose The purpose of this study is to explore the perceptions of key actors in the Caribbean’s hotel industry on the development of business models that are…”
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Multi-phosphine-chelated iron-carbide clusters via redox-promoted ligand exchange on an inert hexa-iron-carbide carbonyl cluster, Fe6(μ6-C)(μ2-CO)4(CO)122 by Cobb, Caitlyn R, Ngo, Ren K, Dick, Emily J, Lynch, Vincent M, Rose, Michael J

“…We report the reactivity, structures and spectroscopic characterization of reactions of phosphine-based ligands (mono-, di- and tri-dentate) with iron-carbide…”
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A Multidisciplinary Approach to Improving the Pediatric Discharge Process by Jubic, Kayla, Dick, Emily, Moelber, Carrie

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A Multidisciplinary Approach to Improving the Pediatric Discharge Process by Jubic, Kayla, Dick, Emily, Moelber, Carrie

“…A collaborative and multidisciplinary shared responsibility with providing discharge information to pediatric patients/families can support successful…”
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Family Studies of Whim Syndrome by Dale, David C., Dick, Emily, Kelley, Merideth L., Makaryan, Vahagn, Connelly, Jim, Bolyard, Audrey Anna

“…Background: WHIM syndrome (warts, hypogammaglobulinemia, immunodeficiency, myelokathexis) is a very rare autosomal dominant immunodeficiency disorder…”
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Family Studies of WHIM Syndrome by Dale, David C., Dick, Emily, Kelley, Merideth, Makaryan, Vahagn, Connelly, Jim, Bolyard, Audrey Anna

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X4P-001: A Novel Molecularly-Targeted Oral Therapy for Whim Syndrome by Dale, David, Bolyard, Audrey Anna, Dick, Emily, Kelley, Merideth L., Makaryan, Vahagn, Johnson, Ramsey, Gan, Lu, Parasuraman, Sudha

“…Background: WHIM syndrome (WHIMs; Warts, Hypogammaglobulinemia, Infections, Myelokathexis) is a rare autosomal dominant immunodeficiency disease attributable…”
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Determination of Phase 3 Dose for X4P-001 in Patients with WHIM Syndrome by Dale, David C, Firkin, Frank Caleb, Bolyard, Audrey Anna, Kelley, Merideth L., Dick, Emily, Hartmann, Sonja, Brown, Karen, Ebrahim, Tarek M, Gorelick, Kenneth J, Parasuraman, Sudha

“…Background: WHIM (Warts, Hypogammaglobulinemia, Infections, Myelokathexis) Syndrome is a serious, ultrarare genetic disorder caused by a gain-of-function…”
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Directed Differentiation of Human Embryonic Stem Cells to Interrogate the Cardiac Gene Regulatory Network by Dixon, James E, Dick, Emily, Rajamohan, Divya, Shakesheff, Kevin M, Denning, Chris

“…The limited ability of the heart to regenerate has prompted development of new systems to produce cardiomyocytes for therapeutics. While differentiation of…”
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Abstract 4902: A mouse GITRL fusion protein drives T-cell activation and antitumor activity in preclinical mouse models of cancer by Leyland, Rebecca, Watkins, Amanda, Mulgrew, Kathy A., Bamber, Lisa, Tigue, Natalie J., Dick, Emily, Holoweckyj, Nick, Young, Lesley, Morrow, Michelle, Hammond, Scott A., Leow, Ching Ching, Wilkinson, Robert W., Stewart, Ross

“…Abstract GITR is a member of the TNFR superfamily of proteins and is expressed on resting regulatory T-cells and on other T-cells following activation. Signals…”
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