Search Results - "Dichtl, Karl"

Toxic eburicol accumulation drives the antifungal activity of azoles against Aspergillus fumigatus by Elsaman, Hesham, Golubtsov, Evgeny, Brazil, Sean, Ng, Natanya, Klugherz, Isabel, Martin, Ronny, Dichtl, Karl, Müller, Christoph, Wagener, Johannes

“…Azole antifungals inhibit the sterol C14-demethylase (CYP51/Erg11) of the ergosterol biosynthesis pathway. Here we show that the azole-induced synthesis of…”
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A comparison of two MALDI-TOF MS based assays for the detection of carbapenemases in Enterobacterales by Uitz, Christine, Luxner, Josefa, Friedl, Simone, Leitner, Eva, Grisold, Andrea, Zarfel, Gernot, Steinmetz, Ivo, Dichtl, Karl

“…Carbapenem resistant (CRE) and carbapenemase producing Enterobacterales (CPE) in particular, represent a major threat for healthcare systems worldwide. Rapid,…”
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The response regulator Skn7 of Aspergillus fumigatus is essential for the antifungal effect of fludioxonil by Schruefer, Sebastian, Böhmer, Isabella, Dichtl, Karl, Spadinger, Anja, Kleinemeier, Christoph, Ebel, Frank

“…Aspergillus fumigatus is an important fungal pathogen that represents a major threat for severely immunocompromised patients. Cases of invasive aspergillosis…”
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A retrospective evaluation of the Euroarray STI-11 multiplex system for the detection of eight STI causing agents by Dichtl, Karl, Osterman, Andreas, Forster, Johannes, Jakob, Lena, Suerbaum, Sebastian, Flaig, Michael J., Schubert, Sören, Wagener, Johannes

“…With an incidence of more than > 1,000,000/day, sexually transmitted diseases remain a major challenge for health care systems worldwide. To reduce disease…”
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Peroxiredoxin Asp f3 Is Essential for Aspergillus fumigatus To Overcome Iron Limitation during Infection by Brantl, Victor, Boysen, Jana M, Yap, Annie, Golubtsov, Evgeny, Ruf, Dominik, Heinekamp, Thorsten, Straßburger, Maria, Dichtl, Karl, Haas, Hubertus, Hillmann, Falk, Wagener, Johannes

“…Aspergillus fumigatus is an important fungal pathogen that causes allergic reactions but also life-threatening infections. One of the most abundant A…”
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Head-to-Head Comparison of Nine Assays for the Detection of Anti- Echinococcus Antibodies: A Retrospective Evaluation by Mattwich, Carolina, Huber, Kristina, Bretzel, Gisela, Suerbaum, Sebastian, Wieser, Andreas, Dichtl, Karl

“…BackgroundEchinococcosis is a neglected tropical disease that is severely underdiagnosed in resource-limited settings. In developed countries, diagnosing…”
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Evaluation of a Novel CLIA Monotest Assay for the Detection of Anti-Hepatitis E Virus-IgG and IgM: A Retrospective Comparison with a Line Blot and an ELISA by Dichtl, Karl, Zimmermann, Julia, Koeppel, Martin B., Böhm, Stephan, Osterman, Andreas

“…Despite the increasing relevance of Hepatitis E, an emerging disease endemic in developing and with increasing numbers of sporadic cases in industrialized…”
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Performance of Multiplex PCR and β-1,3-D-Glucan Testing for the Diagnosis of Candidemia by Koc, Özlem, Kessler, Harald H, Hoenigl, Martin, Wagener, Johannes, Suerbaum, Sebastian, Schubert, Sören, Dichtl, Karl

“…Bloodstream infections caused by Candida yeasts (candidemia) are associated with high morbidity and mortality. Diagnosis remains challenging, with the current…”
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Molecular Epidemiology of Mycobacterium abscessus Isolates Recovered from German Cystic Fibrosis Patients by Wetzstein, Nils, Diricks, Margo, Kohl, Thomas A., Wichelhaus, Thomas A., Andres, Sönke, Paulowski, Laura, Schwarz, Carsten, Lewin, Astrid, Kehrmann, Jan, Kahl, Barbara C., Dichtl, Karl, Hügel, Christian, Eickmeier, Olaf, Smaczny, Christina, Schmidt, Annika, Zimmermann, Stefan, Nährlich, Lutz, Hafkemeyer, Sylvia, Niemann, Stefan, Maurer, Florian P., Hogardt, Michael

“…Infections due to Mycobacterium abscessus are a major cause of mortality and morbidity in cystic fibrosis (CF) patients. Furthermore, M. abscessus has been…”
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Erratum for Rothe et al., "Are enterococcal bloodstream infections an independent risk factor for a poorer 5-year survival or just a marker for severity of illness?-The Munich multicentric enterococci cohort" by Rothe, Kathrin, Bachfischer, Tobias, Karapetyan, Siranush, Hapfelmeier, Alexander, Wurst, Milena, Gleich, Sabine, Dichtl, Karl, Schmid, Roland M, Triebelhorn, Julian, Wagner, Laura, Erber, Johanna, Voit, Florian, Burgkart, Rainer, Obermeier, Andreas, Seybold, Ulrich, Busch, Dirk H, Rämer, Patrick C, Spinner, Christoph D, Schneider, Jochen

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Are enterococcal bloodstream infections an independent risk factor for a poorer 5-year survival or just a marker for severity of illness?-The Munich multicentric enterococci cohort by Rothe, Kathrin, Bachfischer, Tobias, Karapetyan, Siranush, Hapfelmeier, Alexander, Wurst, Milena, Gleich, Sabine, Dichtl, Karl, Schmid, Roland M, Triebelhorn, Julian, Wagner, Laura, Erber, Johanna, Voit, Florian, Burgkart, Rainer, Obermeier, Andreas, Seibold, Ulrich, Busch, Dirk H, Rämer, Patrick C, Spinner, Christoph D, Schneider, Jochen

“…The present study provides a substantial contribution to literature, showing that patients with enterococcal bloodstream infections (BSI) have a lower survival…”
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Comparison of β-D-Glucan and Galactomannan in Serum for Detection of Invasive Aspergillosis: Retrospective Analysis with Focus on Early Diagnosis by Dichtl, Karl, Forster, Johannes, Ormanns, Steffen, Horns, Heidi, Suerbaum, Sebastian, Seybold, Ulrich, Wagener, Johannes

“…The early diagnosis of invasive aspergillosis (IA) relies mainly on computed tomography imaging and testing for fungal biomarkers such as galactomannan (GM)…”
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Cell wall integrity signalling in human pathogenic fungi by Dichtl, Karl, Samantaray, Sweta, Wagener, Johannes

“…Summary Fungi are surrounded by a rigid structure, the fungal cell wall. Its plasticity and composition depend on active regulation of the underlying…”
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Evaluation of a Novel Aspergillus Antigen Enzyme-Linked Immunosorbent Assay by Dichtl, Karl, Seybold, Ulrich, Ormanns, Steffen, Horns, Heidi, Wagener, Johannes

“…Invasive aspergillosis (IA) is a life-threatening infection that mainly occurs in immunocompromised patients. Here, we compared the novel -specific…”
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Siderophores: a potential role as a diagnostic for invasive fungal disease by Kriegl, Lisa, Havlicek, Vladimir, Dichtl, Karl, Egger, Matthias, Hoenigl, Martin

“…Invasive fungal diseases (IFDs) such as invasive aspergillosis continue to be associated with high morbidity and mortality while presenting significant…”
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Deciphering cell wall integrity signalling in Aspergillus fumigatus: identification and functional characterization of cell wall stress sensors and relevant Rho GTPases by Dichtl, Karl, Helmschrott, Christoph, Dirr, Franziska, Wagener, Johannes

“…Summary The fungal cell wall, a conserved and highly dynamic structure, is essential for virulence and viability of fungal pathogens and is an important…”
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Serological biomarkers of candidemia: a retrospective evaluation of three assays by Dichtl, Karl, Seybold, Ulrich, Wagener, Johannes

“…Purpose Serologic testing allows for rapid detection of candidemia. More data are needed for the Virion\Serion ELISA antigen test (Ag), Hemkit Candida IHA…”
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A novel microarray-based PCR assay for the detection of HSV-1, HSV-2, and VZV skin infections: A retrospective analysis by Dichtl, Karl, Osterman, Andreas, Barry, Rachel, Wagener, Johannes

“…Prevalence of HSV-1, HSV-2, and VZV infection ranges from 20% to 90%. Viral reactivation is common and results in a significant individual and socioeconomic…”
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Siderophores: a potential role as a diagnostic for invasive fungal disease by Kriegl, Lisa, Havlicek, Vladimir, Dichtl, Karl, Egger, Matthias, Hoenigl, Martin

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Evaluation of a Turbidimetric β-d-Glucan Test for Detection of Pneumocystis jirovecii Pneumonia by Dichtl, Karl, Seybold, Ulrich, Wagener, Johannes

“…Currently, diagnosis of pneumonia (PJP) relies on analysis of lower respiratory specimens, either by microscopy or quantitative real-time PCR (qPCR). Thus,…”
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