Search Results - "Dichmann, S."

The Alternative Splicing Regulator Tra2b Is Required for Somitogenesis and Regulates Splicing of an Inhibitory Wnt11b Isoform by Dichmann, Darwin S., Walentek, Peter, Harland, Richard M.

“…Alternative splicing is pervasive in vertebrates, yet little is known about most isoforms or their regulation. transformer-2b (tra2b) encodes a splicing…”
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fus/TLS orchestrates splicing of developmental regulators during gastrulation by Dichmann, Darwin S, Harland, Richard M

“…Here we investigated the function of the atypical RNA-binding protein fus/TLS (fused in sarcoma/translocated in sarcoma) during early frog development. We…”
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Lower Blood Glucose, Hyperglucagonemia, and Pancreatic α Cell Hyperplasia in Glucagon Receptor Knockout Mice by Gelling, R. W., Du, X. Q., Dichmann, D. S., Rømer, J., Huang, H., Cui, L., Obici, S., Tang, B., Holst, J. J., Fledelius, C., Johansen, P. B., Rossetti, L., Jelicks, L. A., Serup, P., Nishimura, E., Charron, M. J.

“…Glucagon, the counter-regulatory hormone to insulin, is secreted from pancreatic α cells in response to low blood glucose. To examine the role of glucagon in…”
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Genome of the Western Clawed Frog Xenopus tropicalis by Hellsten, Uffe, Harland, Richard M, Gilchrist, Michael J, Hendrix, David, Jurka, Jerzy, Kapitonov, Vladimir, Ovcharenko, Ivan, Putnam, Nicholas H, Shu, Shengqiang, Taher, Leila, Blitz, Ira L, Blumberg, Bruce, Dichmann, Darwin S, Dubchak, Inna, Amaya, Enrique, Detter, John C, Fletcher, Russell, Gerhard, Daniela S, Goodstein, David, Graves, Tina, Grigoriev, Igor V, Grimwood, Jane, Kawashima, Takeshi, Lindquist, Erika, Lucas, Susan M, Mead, Paul E, Mitros, Therese, Ogino, Hajime, Ohta, Yuko, Poliakov, Alexander V, Pollet, Nicolas, Robert, Jacques, Salamov, Asaf, Sater, Amy K, Schmutz, Jeremy, Terry, Astrid, Vize, Peter D, Warren, Wesley C, Wells, Dan, Wills, Andrea, Wilson, Richard K, Zimmerman, Lyle B, Zorn, Aaron M, Grainger, Robert, Grammer, Timothy, Khokha, Mustafa K, Richardson, Paul M, Rokhsar, Daniel S

“…The western clawed frog Xenopus tropicalis is an important model for vertebrate development that combines experimental advantages of the African clawed frog…”
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Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation by Heller, R. Scott, Dichmann, Darwin S., Jensen, Jan, Miller, Chris, Wong, Gordon, Madsen, Ole D., Serup, Palle

“…It is well established that gut and pancreas development depend on epithelial‐mesenchymal interactions. We show here that several Wnt, Frizzled, and secreted…”
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Expression cloning in Xenopus identifies RNA‐binding proteins as regulators of embryogenesis and Rbmx as necessary for neural and muscle development by Dichmann, Darwin S., Fletcher, Russell B., Harland, Richard M.

“…We have performed an expression cloning screen in Xenopus laevis with the aim of isolating novel gene activities from the neural plate. Of 8,064 clones…”
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The P2 purinergic receptors of human dendritic cells: identification and coupling to cytokine release by Ferrari, Davide, La Sala, Andrea, Chiozzi, Paola, Morelli, Anna, Falzoni, Simonetta, Girolomoni, Giampiero, Idzko, Marco, Dichmann, Stefan, Norgauer, Johannes, Di Virgilio, Francesco

“…ABSTRACT We investigated the expression of purinoceptors in human dendritic cells, providing functional, pharmacological, and biochemical evidence that…”
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The atypical RNA-binding protein Taf15 regulates dorsoanterior neural development through diverse mechanisms in Xenopus tropicalis by DeJong, Caitlin S, Dichmann, Darwin S, Exner, Cameron R T, Xu, Yuxiao, Harland, Richard M

“…The FET family of atypical RNA-binding proteins includes Fused in sarcoma (FUS), Ewing's sarcoma (EWS) and the TATA-binding protein-associate factor 15…”
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Deletion of the sclerotome-enriched lncRNA PEAT augments ribosomal protein expression by Stafford, David A., Dichmann, Darwin S., Chang, Jessica K., Harland, Richard M.

“…To define a complete catalog of the genes that are activated during mouse sclerotome formation, we sequenced RNA from embryonic mouse tissue directed to form…”
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Analysis of pancreatic endocrine development in GDF11‐deficient mice by Dichmann, Darwin S., Yassin, Hani, Serup, Palle

“…Here, we examine the role of GDF11 in pancreatic development. Using in situ hybridization and reverse transcriptase‐polymerase chain reaction analyses, we show…”
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Fractalkine induces chemotaxis and actin polymerization in human dendritic cells by Dichmann, S, Herouy, Y, Purlis, D, Rheinen, H, Gebicke-Härter, P, Norgauer, J

“…Dendritic cells (DCs) are considered as the principle initiators of immune responses by virtue of their ability to migrate into target sites, process antigens…”
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Microglial chemokines and chemokine receptors by Gebicke-Haerter, P J, Spleiss, O, Ren, L Q, Li, H, Dichmann, S, Norgauer, J, Boddeke, H W

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Nkx6 genes pattern the frog neural plate and Nkx6.1 is necessary for motoneuron axon projection by Dichmann, Darwin S., Harland, Richard M.

“…Neuronal subtypes originate from an undifferentiated neural epithelium that is progressively divided into progenitor domains by homeodomain transcription…”
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Autologous platelet-derived wound healing factor promotes angiogenesis via alphavbeta3-integrin expression in chronic wounds by Herouy, Y, Mellios, P, Bandemir, E, Stetter, C, Dichmann, S, Idzko, M, Hofmann, C, Vanscheidt, W, Schopf, E, Norgauer, J

“…Healing of venous leg ulcers depends on the adhesive interaction and formation of new vascular cells. Angiogenesis on the surface of angiogenic blood vessels…”
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Human dendritic cells are a physiological source of the chemotactic arachidonic acid metabolite 5-oxo-eicosatetraenoic acid by Zimpfer, U, Dichmann, S, Termeer, C C, Simon, J C, Schröder, J M, Norgauer, J

“…The arachidonic acid metabolite, 5-oxo-eicosatetraenoic acid (5-oxo-ETE), is a potent chemotaxin for neutrophils and eosinophils. The aim of this study was to…”
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Unspecific Labeling of Pancreatic Islets by Antisera Against Fibroblast Growth Factors and Their Receptors by Dichmann, Darwin S, Rescan, Claude, Frandsen, Ulrik, Serup, Palle

“…Six distinct fibroblast growth factors (FGF5) have been detected in pancreatic islets by immunohistochemistry (IHC) using commercially available antisera. We…”
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Activation of the Respiratory Burst in Human Eosinophils by Chemotaxins Requires Intracellular Calcium Fluxes by Elsner, Jörn, Dichmann, Stefan, Kapp, Alexander

“…Eosinophils represent major effector cells in the allergic inflammatory response. Following activation, these cells are capable of mediating tissue damage,…”
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Distinct Amplification of the C5a‐Receptor Pathways in Normodense and Hypodense Eosinophils of Patients with Atopic Dermatitis by Czech, W., Dichmann, S., Herouy, Y., Rheinen, H., Elsner, J., Kapp, A., Norgauer, J.

“…In patients with atopic dermatitis two different types of blood eosinophils with distinct density can be isolated. The normodense cells represent the huge…”
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Expression and misexpression of members of the FGF and TGFβ families of growth factors in the developing mouse pancreas by Dichmann, Darwin S., Miller, Christopher P., Jensen, Jan, Scott Heller, R., Serup, Palle

“…We have performed a high‐capacity, semiquantitative, reverse transcriptase‐polymerase chain reaction screen for expression of fibroblast growth factor (FGF)…”
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Nucleotides induce chemotaxis and actin polymerization in immature but not mature human dendritic cells via activation of pertussis toxin–sensitive P2y receptors by Idzko, Marco, Dichmann, Stefan, Ferrari, Davide, Di Virgilio, Francesco, la Sala, Andrea, Girolomoni, Giampiero, Panther, Elisabeth, Norgauer, Johannes

“…Dendritic cells (DCs) are considered the principal initiators of immune response because of their ability to migrate into peripheral tissues and lymphoid…”
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