Search Results - "Dice, J Fred"

Chaperone-Mediated Autophagy by Dice, J. Fred

“…Chaperone-mediated autophagy (CMA) is a lysosomal pathway of proteolysis that is responsible for the degradation of 30% of cytosolic proteins under conditions…”
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Proteolytic and lipolytic responses to starvation by Finn, Patrick F., Dice, J. Fred

“…Mammals survive starvation by activating proteolysis and lipolysis in many different tissues. These responses are triggered, at least in part, by changing…”
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Chaperone-mediated autophagy is defective in mucolipidosis type IV by Venugopal, Bhuvarahamurthy, Mesires, Nicholas T., Kennedy, John C., Curcio-Morelli, Cyntia, LaPlante, Janice M., Dice, J. Fred, Slaugenhaupt, Susan A.

“…Mucolipidosis type IV (MLIV) is a lysosomal storage disorder caused by mutations in the MCOLN1 gene, a member of the transient receptor potential (TRP) cation…”
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Ketone Bodies Stimulate Chaperone-mediated Autophagy by Finn, Patrick F, Dice, J Fred

“…Chaperone-mediated autophagy (CMA) is a selective lysosomal protein degradative process that is activated in higher organisms under conditions of prolonged…”
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Effects of Small Molecules on Chaperone-Mediated Autophagy by Finn, Patrick F., Mesires, Nicholas T., Vine, Michaela, Dice, J. Fred

“…Autophagy, including macroautophagy (MA), chaperone-mediated autophagy (CMA), crinophagy, pexophagy and microautophagy, are processes by which cells select…”
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A Receptor for the Selective Uptake and Degradation of Proteins by Lysosomes by Cuervo, Ana Maria, Dice, J. Fred

“…Multiple pathways of protein degradation operate within cells. A selective protein import pathway exists for the uptake and degradation of particular cytosolic…”
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Unifying Nomenclature for the Isoforms of the Lysosomal Membrane Protein LAMP‐2 by Eskelinen, Eeva‐Liisa, Cuervo, Ana Maria, Taylor, Matthew R.G., Nishino, Ichizo, Blum, Janice S., Dice, J. Fred, Sandoval, Ignacio V., Lippincott‐Schwartz, Jennifer, August, J. Thomas, Saftig, Paul

“…The present nomenclature of the splice variants of the lysosome‐associated membrane protein type 2 (LAMP‐2) is confusing. The LAMP‐2a isoform is uniformly…”
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An Intralysosomal hsp70 Is Required for a Selective Pathway of Lysosomal Protein Degradation by Agarraberes, Fernando A., Terlecky, Stanley R., Dice, J. Fred

“…Previous studies have implicated the heat shock cognate (hsc) protein of 73 kD (hsc73) in stimulating a lysosomal pathway of proteolysis that is selective for…”
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Akt and mammalian target of rapamycin regulate separate systems of proteolysis in renal tubular cells by WEN SHEN, BROWN, Nikia S, FINN, Patrick F, FRED DICE, J, FRANCH, Harold A

“…EGF suppresses proteolysis via class 1 phosphatidylinositol 3-kinase (PI3K) in renal tubular cells. EGF also increases the abundance of glycolytic enzymes…”
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Mechanisms of chaperone-mediated autophagy by Majeski, Amy E., Fred Dice, J.

“…Chaperone-mediated autophagy is one of several lysosomal pathways of proteolysis. This pathway is activated by physiological stresses such as prolonged…”
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Extracellular matrix remodeling—Methods to quantify cell–matrix interactions by Abraham, Leah C, Dice, J. Fred, Finn, Patrick F, Mesires, Nicholas T, Lee, Kyongbum, Kaplan, David L

“…Abstract Tissue turnover during wound healing, regeneration or integration of biomedical materials depends on the rate and extent of materials trafficking into…”
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Age-related Decline in Chaperone-mediated Autophagy by Cuervo, Ana Maria, Dice, J. Fred

“…Intracellular protein degradation rates decrease with age in many tissues and organs. In cultured cells, chaperone-mediated autophagy, which is responsible for…”
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A molecular chaperone complex at the lysosomal membrane is required for protein translocation by Agarraberes, F A, Dice, J F

“…A group of cytosolic proteins are targeted to lysosomes for degradation in response to serum withdrawal or prolonged starvation by a process termed…”
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Phagocytosis and remodeling of collagen matrices by Abraham, Leah C., Dice, J. Fred, Lee, Kyongbum, Kaplan, David L.

“…The biodegradation of collagen and the deposition of new collagen-based extracellular matrices are of central importance in tissue remodeling and function…”
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Cathepsin A regulates chaperone-mediated autophagy through cleavage of the lysosomal receptor by Cuervo, Ana Maria, Mann, Linda, Bonten, Erik J., d'Azzo, Alessandra, Dice, J. Fred

“…Protective protein/cathepsin A (PPCA) has a serine carboxypeptidase activity of unknown physiological function. We now demonstrate that this protease activity…”
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Artophagy: The art of autophagy-Macroautophagy by Dice, J. Fred, Klionsky, Daniel J.

“…Many of us have sketched (by hand or on the computer) depictions of macroautophagy; however, how often have we considered which elements in the drawing are key…”
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A Population of Rat Liver Lysosomes Responsible for the Selective Uptake and Degradation of Cytosolic Proteins by Cuervo, Ana Maria, Dice, J.Fred, Knecht, Erwin

“…Two populations of rat liver lysosomes can be distinguished on the basis of their density. A major difference between these populations is that one contains…”
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Chaperone-mediated autophagy: The heretofore untold story of J. Fred "Paulo" Dice by Klionsky, Daniel J., Dice, J. Fred

“…The best-characterized process of autophagy is macroautophagy. Many an article or talk has started with the phrase "...macroautophagy, hereafter referred to as…”
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Roles of Molecular Chaperones in Protein Degradation by Hayes, Sandra A., Dice, J. Fred

“…Hayes and Dice examine the roles of molecular chaperones and protein degradation in prokaryotes and eukaryotes. Specific molecular chaperones appear to be…”
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Selective Degradation of Annexins by Chaperone-mediated Autophagy by Cuervo, Ana Maria, Gomes, Aldrin V., Barnes, Junor A., Dice, J. Fred

“…Annexins are a family of proteins that bind phospholipids in a calcium-dependent manner. Analysis of the sequences of the different members of the annexin…”
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