Search Results - "Dibrino, J N"

Synthesis, in vitro and in vivo activity of novel 9-deoxo-9a-AZA-9a-homoerythromycin A derivatives; a new class of macrolide antibiotics, the azalides by Bright, G M, Nagel, A A, Bordner, J, Desai, K A, Dibrino, J N, Nowakowska, J, Vincent, L, Watrous, R M, Sciavolino, F C, English, A R

“…A series of erythromycin A-derived semisynthetic antibiotics, featuring incorporation of a basic nitrogen atom into a ring expanded (15-membered) macrocyclic…”
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trans-3-benzyl-4-hydroxy-7-chromanylbenzoic acid derivatives as antagonists of the leukotriene B4 (LTB4) receptor by REITER, L. A, KOCH, K, DIBRINO, J. N, DOMINY, B. W, FARRELL, C. A, HINGORANI, G. P, MARTINELLI, G. J, RAMCHANDANI, M, WRIGHT, K. F, PISCOPIO, A. D, SHOWELL, H. J, ALPERT, R, BIGGERS, M. S, CHAMBERS, R. J, CONKLYN, M. J, COOPER, K, CORTINA, S. R

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Pyrazolinone-piperidine dipeptide growth hormone secretagogues (GHSs): Discovery of capromorelin by Carpino, Philip A, Lefker, Bruce A, Toler, Steven M, Pan, Lydia C, Hadcock, John R, Cook, Ewell R, DiBrino, Joseph N, Campeta, Anthony M, DeNinno, Shari L, Chidsey-Frink, Kristin L, Hada, William A, Inthavongsay, John, Mangano, F.Michael, Mullins, Michelle A, Nickerson, David F, Ng, Oicheng, Pirie, Christine M, Ragan, John A, Rose, Colin R, Tess, David A, Wright, Ann S, Yu, Li, Zawistoski, Michael P, DaSilva-Jardine, Paul A, Wilson, Theresa C, Thompson, David D

“…Novel pyrazolinone-piperidine dipeptide derivatives were synthesized and evaluated as growth hormone secretagogues (GHSs). Two analogues, capromorelin ( 5,…”
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trans-3-Benzyl-4-hydroxy-7-chromanylbenzoic acid derivatives as antagonists of the leukotriene B4 (LTB4) receptor by Reiter, L A, Koch, K, Piscopio, A D, Showell, H J, Alpert, R, Biggers, M S, Chambers, R J, Conklyn, M J, Cooper, K, Cortina, S R, Dibrino, J N, Dominy, B W, Farrell, C A, Hingorani, G P, Martinelli, G J, Ramchandani, M, Wright, K F

“…The SAR of a series of 2-(7-chromanyl)benzoic acids has been investigated with the aim of identifying potent and selective LTB4 receptor antagonists that…”
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Discovery and biological characterization of capromorelin analogues with extended half-lives by Carpino, Philip A., Lefker, Bruce A., Toler, Steven M., Pan, Lydia C., Hadcock, John R., Murray, Marianne C., Cook, Ewell R., DiBrino, Joseph N., DeNinno, Shari L., Chidsey-Frink, Kristin L., Hada, William A., Inthavongsay, John, Lewis, Sharon K., Mangano, F.Michael, Mullins, Michelle A., Nickerson, David F., Ng, Oicheng, Pirie, Christine M., Ragan, John A., Rose, Colin R., Tess, David A., Wright, Ann S., Yu, Li, Zawistoski, Michael P., Pettersen, John C., DaSilva-Jardine, Paul A., Wilson, Theresa C., Thompson, David D.

“…New tert-butyl, picolyl and fluorinated analogues of capromorelin ( 3), a short-acting growth hormone secretagogue (GHS), were prepared as part of a program to…”
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trans-3-Benzyl-4-hydroxy-7-chromanylbenzoic acid derivatives as antagonists of the leukotriene B 4 (LTB 4) receptor by Reiter, Lawrence A., Koch, Kevin, Piscopio, Anthony D., Showell, Henry J., Alpert, Robbin, Biggers, Michael S., Chambers, Robert J., Conklyn, Maryrose J., Cooper, Kelvin, Cortina, Santo R., Dibrino, Joseph N., Dominy, Beryl W., Farrell, Cathy A., Hingorani, Gary P., Martinelli, Gary J., Ramchandani, Mukesh, Wright, Kathyrn F.

“…The SAR of a series of 2-(7-chromanyl)benzoic acids has been investigated with the aim of identifying potent and selective LTB 4 receptor antagonists that…”
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