Search Results - "Dibben, Sian"

Methods comparison for high-resolution transcriptional analysis of archival material on Affymetrix Plus 2.0 and Exon 1.0 microarrays by Linton, Kim, Hey, Yvonne, Dibben, Sian, Miller, Crispin, Freemont, Anthony, Radford, John, Pepper, Stuart

“…Microarray gene expression profiling of formalin-fixed paraffin-embedded (FFPE) tissues is a new and evolving technique. This report compares transcript…”
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Implications for Powering Biomarker Discovery Studies by Dibben, Sian M, Holt, Robert J, Davison, Timothy S, Wilson, Claire L, Taylor, Janet, Paul, Ian, McManus, Kieran, Kelly, Paul J, Proutski, Vitali, Harkin, D. Paul, Kerr, Peter, Fennell, Dean A, James, Jacqueline A, Kennedy, Richard D

“…This study examined variations in gene expression between FFPE blocks within tumors of individual patients. Microarray data were used to measure tumor…”
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Gene Expression Signature for Prediction of Golimumab Response in a Phase 2a Open-Label Trial of Patients With Ulcerative Colitis by Telesco, Shannon E., Brodmerkel, Carrie, Zhang, Hongyan, Kim, Lilianne (Lee-Lian), Johanns, Jewel, Mazumder, Abhijit, Li, Katherine, Baribaud, Frédéric, Curran, Mark, Strauss, Richard, Paxson, Bethany, Plevy, Scott, Davison, Timothy, Knight, Laura, Dibben, Sian, Schreiber, Stefan, Sandborn, William, Rutgeerts, Paul, Siegel, Corey A., Reinisch, Walter, Greenbaum, Linda E.

“…Golimumab, a tumor necrosis factor antagonist, is an effective treatment for patients with moderate-to-severe ulcerative colitis (UC); however, more than 50%…”
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An annotation infrastructure for the analysis and interpretation of Affymetrix exon array data by Okoniewski, Michał J, Yates, Tim, Dibben, Siân, Miller, Crispin J

“…Affymetrix exon arrays contain probesets intended to target every known and predicted exon in the entire genome, posing significant challenges for…”
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