Search Results - "Dibb, K.M"

Differences in intracellular calcium homeostasis between atrial and ventricular myocytes by Walden, A.P, Dibb, K.M, Trafford, A.W

“…Abstract The role that Ca2+ plays in ventricular excitation contraction coupling is well defined and much is known about the marked differences in the…”
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The generation and validation of two NKX2-5 fluorescent reporter human embryonic stem cell lines: UMANe002-A-1 and UMANe002-A-2 by Douglas, M., O'Loughlin, C., Lynch, A.T., Prialgauskaite, R., Adamson, A.D., Dibb, K.M., Kimber, S.J., Birket, M.J.

“…•5' and 3' GFP knock-in NKX2-5 reporter hESC lines.•Robust expression of GFP in cardiac progenitors and myocytes.•Valuable tools for development and disease…”
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Analysis of cellular calcium fluxes in cardiac muscle to understand calcium homeostasis in the heart by Dibb, K.M, Graham, H.K, Venetucci, L.A, Eisner, D.A, Trafford, A.W

“…Abstract Central to controlling intracellular calcium concentration ([Ca2+ ] i ) are a number of Ca2+ transporters and channels with the L-type Ca2+ channel,…”
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K + Activation of Kir3.1/Kir3.4 and Kv1.4 K + Channels Is Regulated by Extracellular Charges by Claydon, T.W., Makary, S.Y., Dibb, K.M., Boyett, M.R.

“…K + activates many inward rectifier and voltage-gated K + channels. In each case, an increase in K + current through the channel can occur despite a reduced…”
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Susceptibility to atrial alternans; a role for transverse (t)-tubule loss in heart failure (HF)? by Madders, G.W.P., Woods, L., Hutchings, D.C., Waddell, C.A., Denham, N., Trafford, A.W., Eisner, D.A., Dibb, K.M.

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Mechanisms underlying enhanced cardiac excitation contraction coupling observed in the senescent sheep myocardium by Dibb, K.M., Rueckschloss, U., Eisner, D.A., Isenberg, G., Trafford, A.W.

“…Ageing related stiffening of the vascular system is believed to be in part responsible for a number of clinical outcomes including hypertension and heart…”
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Enhanced transmural gradient in Ito in a ferret model of heart failure without associated changes in KChIP2b protein expression by Diffley, L.C., Dibb, K.M., Graham, H.K., Trafford, A.W.

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Base of Pore Loop Is Important for Rectification, Activation, Permeation, and Block of Kir3.1/Kir3.4 by Makary, S.M.Y., Claydon, T.W., Dibb, K.M., Boyett, M.R.

“…The Kir3.1/Kir3.4 channel is an inward rectifier, agonist-activated K + channel. The location of the binding site within the channel pore that coordinates…”
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Cs+ block of the cardiac muscarinic K+ channel, GIRK1/GIRK4, is not dependent on the aspartate residue at position 173 by Dibb, K M, Leach, R, Lancaster, M K, Findlay, J B, Boyett, M R

“…Cs+ block of GIRK1/GIRK4 expressed in Xenopus oocytes has been investigated. It has been reported that a negatively charged aspartate residue at position 172…”
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Chapter 128 - Calcium Signaling in Cardiac Muscle by Dibb, K.M., Trafford, A.W., Eisner, D.A.

“…The purpose of this chapter is to provide an overview of aspects of the state of knowledge of calcium signaling. Changes of the amplitude of the calcium…”
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