Search Results - "Dibas, Mohammed I."

Cys-loop receptors: new twists and turns by Lester, Henry A., Dibas, Mohammed I., Dahan, David S., Leite, John F., Dougherty, Dennis A.

“…New hypotheses and predictions have arisen from recent work revealing atomic-scale or near-atomic-scale structures of receptors in the ‘Cys-loop’ superfamily…”
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Conformational Variability of the Glycine Receptor M2 Domain in Response to Activation by Different Agonists by Pless, Stephan A., Dibas, Mohammed I., Lester, Henry A., Lynch, Joseph W.

“…Models describing the structural changes mediating Cys loop receptor activation generally give little attention to the possibility that different agonists may…”
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Single-Molecule Imaging of a Fluorescent Unnatural Amino Acid Incorporated Into Nicotinic Receptors by Pantoja, Rigo, Rodriguez, Erik A., Dibas, Mohammed I., Dougherty, Dennis A., Lester, Henry A.

“…We report on the first, to our knowledge, successful detection of a fluorescent unnatural amino acid (fUAA), Lys(BODIPYFL), incorporated into a membrane…”
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A Fluorophore Attached to Nicotinic Acetylcholine Receptor βM2 Detects Productive Binding of Agonist to the αδ Site by Dahan, David S., Dibas, Mohammed I., Petersson, E. James, Auyeung, Vincent C., Chanda, Baron, Bezanilla, Francisco, Dougherty, Dennis A., Lester, Henry A., Karlin, Arthur

“…To study conformational transitions at the muscle nicotinic acetylcholine (ACh) receptor (nAChR), a rhodamine fluorophore was tethered to a Cys side chain…”
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Stoichiometric analysis of the TM2 6' phenylalanine mutation on desensitization in α1β2 and α1β2γ2 GABAA receptors by GONZALES, Eric B, BELL-HOMER, Cathy L, DIBAS, Mohammed I, HUANG, Ren-Qi, DILLON, Glenn H

“…The presence of phenylalanine (F) at the 6′ position of transmembrane domain 2 (TM2) in the α4 subunit of α4β2 nicotinic receptors enhances desensitization. As…”
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The central nervous system convulsant pentylenetetrazole stimulates γ-aminobutyric acid (GABA)-activated current in picrotoxin-resistant GABA A receptors in HEK293 cells by Dibas, Mohammed I, Dillon, Glenn H

“…We tested the ability of the central nervous system convulsant pentylenetetrazole (PTZ) to inhibit γ-aminobutyric acid (GABA)-gated current in receptors…”
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Pentylenetetrazole-induced inhibition of recombinant gamma-aminobutyric acid type A (GABA(A)) receptors: mechanism and site of action by Huang, R Q, Bell-Horner, C L, Dibas, M I, Covey, D F, Drewe, J A, Dillon, G H

“…Pentylenetetrazole (PTZ) is a central nervous system convulsant that is thought, based on binding studies, to act at the picrotoxin (PTX) site of the…”
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A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site by Dahan, David S, Dibas, Mohammed I, Petersson, E James, Auyeung, Vincent C, Chanda, Baron, Bezanilla, Francisco, Dougherty, Dennis A, Lester, Henry A

“…To study conformational transitions at the muscle nicotinic acetylcholine (ACh) receptor (nAChR), a rhodamine fluorophore was tethered to a Cys side chain…”
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Identification of a Novel Residue within the Second Transmembrane Domain That Confers Use-facilitated Block by Picrotoxin in Glycine α1 Receptors by Dibas, Mohammed I., Gonzales, Eric B., Das, Paromita, Bell-Horner, Cathy L., Dillon, Glenn H.

“…The central nervous system convulsant picrotoxin (PTX) inhibits GABAA and glutamate-gated Cl− channels in a use-facilitated fashion, whereas PTX inhibition of…”
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Stoichiometric analysis of the TM2 6' phenylalanine mutation on desensitization in alpha1beta2 and alpha1beta2gamma2 GABA A receptors by Gonzales, Eric B, Bell-Horner, Cathy L, Dibas, Mohammed I, Huang, Ren-Qi, Dillon, Glenn H

“…The presence of phenylalanine (F) at the 6' position of transmembrane domain 2 (TM2) in the alpha4 subunit of alpha4beta2 nicotinic receptors enhances…”
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Stoichiometric analysis of the TM2 6′ phenylalanine mutation on desensitization in α1β2 and α1β2γ2 GABA A receptors by Gonzales, Eric B., Bell-Horner, Cathy L., Dibas, Mohammed I., Huang, Ren-Qi, Dillon, Glenn H.

“…The presence of phenylalanine (F) at the 6′ position of transmembrane domain 2 (TM2) in the α4 subunit of α4β2 nicotinic receptors enhances desensitization. As…”
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Identification of a novel residue within the second transmembrane domain that confers use-facilitated block by picrotoxin in glycine alpha 1 receptors by Dibas, Mohammed I, Gonzales, Eric B, Das, Paromita, Bell-Horner, Cathy L, Dillon, Glenn H

“…The central nervous system convulsant picrotoxin (PTX) inhibits GABA(A) and glutamate-gated Cl(minus sign) channels in a use-facilitated fashion, whereas PTX…”
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A fluorophore attached to nicotinic acetylcholine receptor betaM2 detects productive binding of agonist to the alphadelta site by Dahan, David S, Dibas, Mohammed I, Petersson, E James, Auyeung, Vincent C

“…To study conformational transitions at the muscle nicotinic acetylcholine (ACh) receptor (nAChR), a rhodamine fluorophore was tethered to a Cys side chain…”
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Identification of a Novel Residue within the Second Transmembrane Domain That Confers Use-facilitated Block by Picrotoxin in Glycine α1 Receptors by Mohammed I. Dibas, Eric B. Gonzales, Paromita Das, Cathy L. Bell-Horner, Glenn H. Dillon

“…The central nervous system convulsant picrotoxin (PTX) inhibits GABA A and glutamate-gated Cl − channels in a use-facilitated fashion, whereas PTX inhibition…”
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The central nervous system convulsant pentylenetetrazole stimulates γ-aminobutyric acid (GABA)-activated current in picrotoxin-resistant GABAA receptors in HEK293 cells by DIBAS, M. I, DILLON, G. H

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Anionic ligand -gated ion channels: The convulsive site and mechanism of action by Dibas, Mohammed I

“…Picrotoxin, a CNS convulsant inhibits all anionic ligand gated ion channels. The mechanism and the binding site for picrotoxin and its related ligands are…”
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