Search Results - "Diaz Escarcega, Rocio"
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G-quadruplex DNA and RNA in cellular senescence
Published in Frontiers in aging (09-10-2024)“…Normal cells divide, are damaged, and are repaired across their lifetime. As cells age, they enter cellular senescence, characterized by a permanent state of…”
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Sex differences in global metabolomic profiles of COVID-19 patients
Published in Cell death & disease (14-05-2022)“…Coronavirus disease (COVID-19), caused by SARS-CoV-2, leads to symptoms ranging from asymptomatic disease to death. Although males are more susceptible to…”
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Sphingosine kinase 2 regulates protein ubiquitination networks in neurons
Published in Molecular and cellular neuroscience (01-09-2024)“…Two sphingosine kinase isoforms, sphingosine kinase 1 (SPHK1) and sphingosine kinase 2 (SPHK2), synthesize the lipid sphingosine-1-phosphate (S1P) by…”
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The Functional Role of Sphingosine Kinase 2
Published in Frontiers in molecular biosciences (14-05-2021)“…Sphingosine-1-phosphate (S1P) is a bioactive lipid molecule that is present in all eukaryotic cells and plays key roles in various extracellular, cytosolic,…”
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Pirh2-dependent DNA damage in neurons induced by the G-quadruplex ligand pyridostatin
Published in The Journal of biological chemistry (01-10-2023)“…Noncanonical base pairing between four guanines (G) within single-stranded G-rich sequences leads to formation of а G-quartet. Self-stacking of G-quartets…”
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The Tardigrade damage suppressor protein Dsup promotes DNA damage in neurons
Published in Molecular and cellular neuroscience (01-06-2023)“…Tardigrades are microscopic invertebrates, which are capable of withstanding extreme environmental conditions, including high levels of radiation. A Tardigrade…”
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Chemotherapy as a risk factor for Alzheimer’s disease
Published in Alzheimer's & dementia (01-12-2022)“…Background Cognitive impairments may occur in cancer patients and survivors during or after chemotherapy. Cognitive deficits associated with neurotoxicity…”
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