Search Results - "Diaz Arias, Jose Angel"

Novel Mutation Hotspots within Non-Coding Regulatory Regions of the Chronic Lymphocytic Leukemia Genome by Mosquera Orgueira, Adrián, Rodríguez Antelo, Beatriz, Díaz Arias, José Ángel, Díaz Varela, Nicolás, Alonso Vence, Natalia, González Pérez, Marta Sonia, Bello López, José Luis

“…Mutations in non-coding DNA regions are increasingly recognized as cancer drivers. These mutations can modify gene expression in cis or by inducing high-order…”
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Personalized Survival Prediction of Patients With Acute Myeloblastic Leukemia Using Gene Expression Profiling by Mosquera Orgueira, Adrián, Peleteiro Raíndo, Andrés, Cid López, Miguel, Díaz Arias, José Ángel, González Pérez, Marta Sonia, Antelo Rodríguez, Beatriz, Alonso Vence, Natalia, Bao Pérez, Laura, Ferreiro Ferro, Roi, Albors Ferreiro, Manuel, Abuín Blanco, Aitor, Fontanes Trabazo, Emilia, Cerchione, Claudio, Martinnelli, Giovanni, Montesinos Fernández, Pau, Mateo Pérez Encinas, Manuel, Luis Bello López, José

“…Acute Myeloid Leukemia (AML) is a heterogeneous neoplasm characterized by cytogenetic and molecular alterations that drive patient prognosis. Currently…”
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Evaluation of the Stellae-123 prognostic gene expression signature in acute myeloid leukemia by Mosquera Orgueira, Adrián, Peleteiro Raíndo, Andrés, Díaz Arias, José Ángel, Antelo Rodríguez, Beatriz, López Riñón, Mónica, Cerchione, Claudio, de la Fuente Burguera, Adolfo, González Pérez, Marta Sonia, Martinelli, Giovanni, Montesinos Fernández, Pau, Pérez Encinas, Manuel Mateo

“…Risk stratification in acute myeloid leukemia (AML) has been extensively improved thanks to the incorporation of recurrent cytogenomic alterations into risk…”
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Personally Tailored Survival Prediction of Patients With Follicular Lymphoma Using Machine Learning Transcriptome-Based Models by Mosquera Orgueira, Adrián, Cid López, Miguel, Peleteiro Raíndo, Andrés, Abuín Blanco, Aitor, Díaz Arias, Jose Ángel, González Pérez, Marta Sonia, Antelo Rodríguez, Beatriz, Bao Pérez, Laura, Ferreiro Ferro, Roi, Aliste Santos, Carlos, Pérez Encinas, Manuel Mateo, Fraga Rodríguez, Máximo Francisco, Cerchione, Claudio, Mozas, Pablo, Bello López, José Luis

“…Follicular Lymphoma (FL) has a 10-year mortality rate of 20%, and this is mostly related to lymphoma progression and transformation to higher grades. In the…”
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A Three-Gene Expression Signature Identifies a Cluster of Patients with Short Survival in Chronic Lymphocytic Leukemia by Díaz Varela, Nicolás, Díaz Arias, José Ángel, Antelo Rodríguez, Beatriz, Mosquera Orgueira, Adrián, Bello López, José Luis

“…Chronic lymphocytic leukemia (CLL) is a lymphoproliferative disorder characterized by its heterogeneous clinical evolution. Despite the discovery of the most…”
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Detection of new drivers of frequent B-cell lymphoid neoplasms using an integrated analysis of whole genomes by Mosquera Orgueira, Adrián, Ferreiro Ferro, Roi, Díaz Arias, José Ángel, Aliste Santos, Carlos, Antelo Rodríguez, Beatriz, Bao Pérez, Laura, Alonso Vence, Natalia, Bendaña López, Ággeles, Abuin Blanco, Aitor, Melero Valentín, Paula, Peleteiro Raindo, And Res, Cid López, Miguel, Pérez Encinas, Manuel Mateo, González Pérez, Marta Sonia, Fraga Rodríguez, Máximo Francisco, Bello López, José Luis

“…B-cell lymphoproliferative disorders exhibit a diverse spectrum of diagnostic entities with heterogeneous behaviour. Multiple efforts have focused on the…”
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Gene expression profiling identifies FLT3 mutation-like cases in wild-type FLT3 acute myeloid leukemia by Mosquera Orgueira, Adrián, Peleteiro Raíndo, Andrés, Cid López, Miguel, Antelo Rodríguez, Beatriz, Díaz Arias, José Ángel, Ferreiro Ferro, Roi, Alonso Vence, Natalia, Bendaña López, Ángeles, Abuín Blanco, Aitor, Bao Pérez, Laura, Melero Valentín, Paula, González Pérez, Marta Sonia, Cerchione, Claudio, Martinelli, Giovanni, Montesinos Fernández, Pau, Pérez Encinas, Manuel Mateo, Bello López, José Luis

“…FLT3 mutation is present in 25-30% of all acute myeloid leukemias (AML), and it is associated with adverse outcome. FLT3 inhibitors have shown improved…”
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P967: A MACHINE LEARNING MODEL FOR RISK PREDICTION IN MULTIPLE MYELOMA PROGRESSING AFTER THE FIRST LINE OF THERAPY by Mosquera‐Orgueira, Adrian, Perez, Marta Sonia Gonzalez, Diaz Arias, Jose Angel, Mateos, Maria‐Victoria

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PB2624: CLINICAL WHOLE EXOM SEQUENCING FOR CONGENITAL PLATELET DISORDERS: ONE SINGLE CENTER EXPERIENCE by Piñeiro, Victor Portela, Mosquera‐Orgueira, Adrian, Mellid, Eugenia Fernandez, Arias, Jose Angel Diaz, Lopez, Miguel Cid, Martin, Rocio Serrano, Llamas, Juan Carlos Vallejo

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Identification of new putative driver mutations and predictors of disease evolution in chronic lymphocytic leukemia by Mosquera Orgueira, Adrián, Antelo Rodríguez, Beatriz, Díaz Arias, José Ángel, Bello López, José Luis

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PB2384: EVALUATION OF NEW MACHINE LEARNING SYSTEMS FOR PROGNOSTICATION BASED ON GENE EXPRESSION SIGNATURES IN MANTLE CELL AND PERIPHERAL T CELL LYMPHOMAS by Mosquera‐Orgueira, Adrian, Angel Diaz Arias, Jose, Serrano Martin, Rocio, Portela Piñeiro, Victor, Peleteiro Raindo, Andres, Cid Lopez, Miguel, Bao Perez, Laura, Sonia Gonzalez Perez, Marta, Mateo Perez Encinas, Manuel, Francisco Fraga Rodriguez, Maximo, Carlos Vallejo Llamas, Juan, Luis Bello Lopez, Jose

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P1234: A PROGNOSTIC MODEL BASED ON GENE EXPRESSION PARAMETERS PREDICTS A BETTER RESPONSE TO BORTEZOMIB‐CONTAINING IMMUNOCHEMOTHERAPY IN DIFFUSE LARGE B‐CELL LYMPHOMA by Mosquera‐Orgueira, Adrian, Arias, Jose Angel Diaz, Serrano Martin, Rocio, Portela Piñeiro, Victor, Cid Lopez, Miguel, Peleteiro Raindo, Andres, Bao Perez, Laura, Perez, Marta Sonia Gonzalez, Encinas, Manuel Mateo Perez, Rodriguez, Maximo Francisco Fraga, Llamas, Juan Carlos Vallejo, Bello Lopez, Jose Luis

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Epigenetic Profiling and Machine Learning for Enhanced Risk Stratification in Pediatric Acute Lymphoblastic Leukemia by Mosquera Orgueira, Adrian, Krali, Olga, Peleteiro Raindo, Andres, Diaz Arias, Jose Angel, Gonzalez Perez, Marta Sonia, Perez Encinas, Manuel, Fernandez Sanmartin, Manuel, Alonso Vence, Natalia, Sinnett, Daniel, Heyman, Mats, Lönnerholm, Gudmar, Norén-Nyström, Ulrika, Schmiegelow, Kjeld, Nordlund, Jessica

“…Introduction: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy with high clinical and biological heterogeneity. Despite advancements…”
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The FLT3-like Gene Expression Signature Predicts Response to Quizartinib in Wild-Type FLT3 Acute Myeloid Leukemia: An Analysis of the Pethema Quiwi Trial by Mosquera Orgueira, Adrian, Perez Encinas, Manuel, Diaz Arias, Jose Angel, Rodriguez Veiga, Rebeca, Bergua Burgues, Juan Miguel, Algarra, Jesús Lorenzo, Botella, Carmen, Perez Simon, Jose Antonio, Bernal, Teresa, Tormo, Mar, Calbacho, Maria, Salamero, Olga, Serrano, Josefina, Noriega, Victor, Lopez Lopez, Juan Antonio, Vives, Susana, Colorado, Mercedes, Lopez Lorenzo, Jose Luis, Vidriales Vicente, Maria, Garcia Boyero, Raimundo, Olave Rubio, Maria Teresa, Herrera Puente, Pilar, Arce, Olga, Barrios Garcia, Manuel, Sayas Lloris, Maria Jose, Polo, Marta, Gomez Roncero, Maria Isabel, Barragan, Eva, Ayala, Rosa, Chillon, Carmen, Calasanz, Maria Jose, Boluda, Blanca, Peleteiro Raindo, Andres, Amigo, Raquel, Martinez Cuadron, David, Labrador, Jorge, Montesinos, Pau

“…Background The identification of predictive biomarkers is crucial for guiding treatment decisions in acute myeloid leukemia (AML). Previously, we identified a…”
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Exploring Potential Molecular Mechanisms of Drug Response in FLT3-ITD Negative AML Patients Treated with Quizartinib Vs Placebo Plus Standard Chemotherapy in the Quiwi Trial by Mosquera Orgueira, Adrian, Perez Encinas, Manuel, Diaz Arias, Jose Angel, Rodriguez Veiga, Rebeca, Bergua Burgues, Juan Miguel, Algarra, Lorenzo, Botella, Carmen, Perez Simon, Jose Antonio, Bernal, Teresa, Tormo, Mar, Calbacho, Maria, Salamero, Olga, Serrano, Josefina, Noriega, Victor, Lopez Lopez, Juan Antonio, Vives, Susana, Colorado, Mercedes, Lopez Lorenzo, Jose Luis, Vidriales Vicente, Maria, Garcia Boyero, Raimundo, Olave Rubio, Maria Teresa, Herrera Puente, Pilar, Arce, Olga, Barrios Garcia, Manuel, Sayas Lloris, Maria Jose, Polo, Marta, Gomez Roncero, Maria Isabel, Barragan, Eva, Ayala, Rosa, Chillon, Carmen, Calasanz, Maria Jose, Boluda, Blanca, Peleteiro Raindo, Andres, Amigo, Raquel, Labrador, Jorge, Martinez Cuadron, David, Montesinos, Pau

“…Introduction Wild-type FLT3 AML presents significant therapeutic challenges due to limited treatment options. The QUIWI trial investigated quizartinib (Quiz)…”
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Improved personalized survival prediction of patients with diffuse large B-cell Lymphoma using gene expression profiling by Mosquera Orgueira, Adrián, Díaz Arias, José Ángel, Cid López, Miguel, Peleteiro Raíndo, Andrés, Antelo Rodríguez, Beatriz, Aliste Santos, Carlos, Alonso Vence, Natalia, Bendaña López, Ángeles, Abuín Blanco, Aitor, Bao Pérez, Laura, González Pérez, Marta Sonia, Pérez Encinas, Manuel Mateo, Fraga Rodríguez, Máximo Francisco, Bello López, José Luis

“…Thirty to forty percent of patients with Diffuse Large B-cell Lymphoma (DLBCL) have an adverse clinical evolution. The increased understanding of DLBCL biology…”
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The association of germline variants with chronic lymphocytic leukemia outcome suggests the implication of novel genes and pathways in clinical evolution by Mosquera Orgueira, Adrián, Antelo Rodríguez, Beatriz, Alonso Vence, Natalia, Díaz Arias, José Ángel, Díaz Varela, Nicolás, Pérez Encinas, Manuel Mateo, Allegue Toscano, Catarina, Goiricelaya Seco, Elena María, Carracedo Álvarez, Ángel, Bello López, José Luis

“…Chronic Lymphocytic Leukemia (CLL) is the most frequent lymphoproliferative disorder in western countries and is characterized by a remarkable clinical…”
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Prognostic Stratification of Multiple Myeloma Using Clinicogenomic Models: Validation and Performance Analysis of the IAC‐50 Model by Mosquera Orgueira, Adrián, González Pérez, Marta Sonia, Díaz Arias, José Ángel, Antelo Rodríguez, Beatriz, Mateos, María‐Victoria

“…A growing need to evaluate risk‐adapted treatments in multiple myeloma (MM) exists. Several clinical and molecular scores have been developed in the last…”
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Time to Treatment Prediction in Chronic Lymphocytic Leukemia Based on New Transcriptional Patterns by Mosquera Orgueira, Adrián, Antelo Rodríguez, Beatriz, Alonso Vence, Natalia, Bendaña López, Ángeles, Díaz Arias, José Ángel, Díaz Varela, Nicolás, González Pérez, Marta Sonia, Pérez Encinas, Manuel Mateo, Bello López, José Luis

“…Chronic lymphocytic leukemia (CLL) is the most frequent lymphoproliferative syndrome in western countries. CLL evolution is frequently indolent, and treatment…”
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Survival prediction and treatment optimization of multiple myeloma patients using machine-learning models based on clinical and gene expression data by Mosquera Orgueira, Adrián, González Pérez, Marta Sonia, Díaz Arias, José Ángel, Antelo Rodríguez, Beatriz, Alonso Vence, Natalia, Bendaña López, Ángeles, Abuín Blanco, Aitor, Bao Pérez, Laura, Peleteiro Raíndo, Andrés, Cid López, Miguel, Pérez Encinas, Manuel Mateo, Bello López, José Luis, Mateos Manteca, Maria Victoria

“…Multiple myeloma (MM) remains mostly an incurable disease with a heterogeneous clinical evolution. Despite the availability of several prognostic scores,…”
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