Search Results - "Diaz‐Gallo, Lina Marcela"

EOMES‐positive CD4+ T cells are increased in PTPN22 (1858T) risk allele carriers by Chemin, Karine, Ramsköld, Daniel, Diaz‐Gallo, Lina‐Marcela, Herrath, Jessica, Houtman, Miranda, Tandre, Karolina, Rönnblom, Lars, Catrina, Anca, Malmström, Vivianne

“…The presence of the PTPN22 risk allele (1858T) is associated with several autoimmune diseases including rheumatoid arthritis (RA). Despite a number of studies…”
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Single-cell profiling of muscle-infiltrating T cells in idiopathic inflammatory myopathies by Argyriou, Alexandra, Horuluoglu, Begum, Galindo-Feria, Angeles Shunashy, Diaz-Boada, Juan Sebastian, Sijbranda, Merel, Notarnicola, Antonella, Dani, Lara, van Vollenhoven, Annika, Ramsköld, Daniel, Nennesmo, Inger, Dastmalchi, Maryam, Lundberg, Ingrid E, Diaz-Gallo, Lina-Marcela, Chemin, Karine

“…Idiopathic inflammatory myopathies (IIM) are rare autoimmune systemic diseases characterized by muscle weakness and the presence of muscle-infiltrating T…”
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Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA‐DRB1 Genotype Associations and Immunological and Clinical Manifestations by Diaz‐Gallo, Lina‐Marcela, Oke, Vilija, Lundström, Emeli, Elvin, Kerstin, Ling Wu, Yee, Eketjäll, Susanna, Zickert, Agneta, Gustafsson, Johanna T., Jönsen, Andreas, Leonard, Dag, Birmingham, Daniel J., Nordmark, Gunnel, Bengtsson, Anders A., Rönnblom, Lars, Gunnarsson, Iva, Yu, Chack‐Yung, Padyukov, Leonid, Svenungsson, Elisabet

“…Objective The heterogeneity of systemic lupus erythematosus (SLE) constitutes clinical and therapeutical challenges. We therefore studied whether unrecognized…”
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Understanding interactions between risk factors, and assessing the utility of the additive and multiplicative models through simulations by Diaz-Gallo, Lina-Marcela, Brynedal, Boel, Westerlind, Helga, Sandberg, Rickard, Ramsköld, Daniel

“…Understanding the genetic background of complex diseases requires the expansion of studies beyond univariate associations. Therefore, it is important to use…”
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The human bone marrow plasma cell compartment in rheumatoid arthritis - Clonal relationships and anti-citrulline autoantibody producing cells by Hensvold, Aase, Horuluoglu, Begum, Sahlström, Peter, Thyagarajan, Radha, Diaz Boada, Juan Sebastian, Hansson, Monika, Mathsson-Alm, Linda, Gerstner, Christina, Sippl, Natalie, Israelsson, Lena, Wedin, Rikard, Steen, Johanna, Klareskog, Lars, Réthi, Bence, Catrina, Anca I., Diaz-Gallo, Lina-Marcela, Malmström, Vivianne, Grönwall, Caroline

“…A majority of circulating IgG is produced by plasma cells residing in the bone marrow (BM). Long-lived BM plasma cells constitute our humoral immune memory and…”
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Differential association of two PTPN22 coding variants with Crohn's disease and ulcerative colitis by Diaz‐Gallo, Lina‐Marcela, Espino‐Paisán, Laura, Fransen, Karin, Gómez‐García, María, van Sommeren, Suzanne, Cardeña, Carlos, Rodrigo, Luis, Mendoza, Juan Luis, Taxonera, Carlos, Nieto, Antonio, Alcain, Guillermo, Cueto, Ignacio, López‐Nevot, Miguel A., Bottini, Nunzio, Barclay, Murray L., Crusius, J. Bart, van Bodegraven, Adriaan A., Wijmenga, Cisca, Ponsioen, Cyriel Y., Gearry, Richard B., Roberts, Rebecca L., Weersma, Rinse K., Urcelay, Elena, Merriman, Tony R., Alizadeh, Behrooz Z., Martin, Javier

“…Background: The PTPN22 gene is an important risk factor for human autoimmunity. The aim of this study was to evaluate for the first time the role of the R263Q…”
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Evidence of new risk genetic factor to systemic lupus erythematosus: the UBASH3A gene by Diaz-Gallo, Lina-Marcela, Sánchez, Elena, Ortego-Centeno, Norberto, Sabio, Jose Mario, García-Hernández, Francisco J, de Ramón, Enrique, González-Gay, Miguel A, Torsten Witte, Anders, Hans-Joachim, González-Escribano, María F, Martin, Javier

“…The ubiquitin associated and Src-homology 3 (SH3) domain containing A (UBASH3a) is a suppressor of T-cell receptor signaling, underscoring antigen presentation…”
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Autoantibodies, polymorphisms in the serotonin pathway, and human leukocyte antigen class II alleles in chronic fatigue syndrome: are they associated with age at onset and specific symptoms? by Ortega-Hernandez, Oscar-Danilo, Cuccia, Mariaclara, Bozzini, Sara, Bassi, Nicola, Moscavitch, Samuel, Diaz-Gallo, Lina-Marcela, Blank, Miri, Agmon-Levin, Nancy, Shoenfeld, Yehuda

“…This study aimed to determine the influence of autoantibodies, polymorphisms in the serotonin pathway, and human leukocyte antigen (HLA) class II genes on age…”
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Independent replication of an association of CNVR7113.6 with Crohn's disease in caucasians by Roberts, Rebecca L., Diaz‐Gallo, Lina‐Marcela, Barclay, Murray L., Gómez‐García, María, Cardeña, Carlos, Merriman, Tony R., Gearry, Richard B., Martin, Javier

“…Background: A recent genome‐wide association study (GWAS) of copy number variants (CNVs) in Crohn's disease (CD) confirmed association of three CNVs. The GWAS…”
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Repurposing antidiabetic drugs for rheumatoid arthritis: results from a two-sample Mendelian randomization study by Qin, Chenxi, Diaz-Gallo, Lina-Marcela, Tang, Bowen, Wang, Yunzhang, Nguyen, Thuy-Dung, Harder, Arvid, Lu, Yi, Padyukov, Leonid, Askling, Johan, Hägg, Sara

“…Despite increasing therapeutic options to treat rheumatoid arthritis (RA), many patients fail to reach treatment targets. The use of antidiabetic drugs like…”
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Anti-phosphatidylserine/prothrombin antibodies and thrombosis associate positively with HLA-DRB113 and negatively with HLA-DRB103 in SLE by Elbagir, Sahwa, Diaz-Gallo, Lina-Marcela, Grosso, Giorgia, Zickert, Agneta, Gunnarsson, Iva, Mahler, Michael, Svenungsson, Elisabet, Rönnelid, Johan

“…Emerging evidence demonstrates that aPS-PT associate with thrombotic events. Genetic predisposition, including HLA-DRB1 alleles, is known to contribute to the…”
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Genome-wide investigation of persistence with methotrexate treatment in early rheumatoid arthritis by Sysojev, Anton Öberg, Saevarsdottir, Saedis, Diaz-Gallo, Lina-Marcela, Silberberg, Gilad N, Alfredsson, Lars, Klareskog, Lars, Baecklund, Eva, Björkman, Lena, Kastbom, Alf, Rantapää-Dahlqvist, Solbritt, Turesson, Carl, Jonsdottir, Ingileif, Stefansson, Kari, Frisell, Thomas, Padyukov, Leonid, Askling, Johan, Westerlind, Helga

“…To investigate the influence of genetic factors on persistence with treatment of early RA with MTX monotherapy. We conducted a genome-wide association study…”
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A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile by Lindelöf, Linnea, Rantapää-Dahlqvist, Solbritt, Lundtoft, Christian, Sandling, Johanna K., Leonard, Dag, Sayadi, Ahmed, Rönnblom, Lars, Enocsson, Helena, Sjöwall, Christopher, Jönsen, Andreas, Bengtsson, Anders A., Hong, Mun-Gwan, Diaz-Gallo, Lina-Marcela, Bianchi, Matteo, Kozyrev, Sergey V., Lindblad-Toh, Kerstin, Nilsson Ekdahl, Kristina, Nilsson, Bo, Gunnarsson, Iva, Svenungsson, Elisabet, Eriksson, Oskar

“…The complement system plays a central role in the pathogenesis of Systemic Lupus Erythematosus (SLE), but most studies have focused on the classical pathway…”
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The spectrum of association in HLA region with rheumatoid arthritis in a diverse Asian population: evidence from the MyEIRA case-control study by Tan, Lay Kim, Too, Chun Lai, Diaz-Gallo, Lina Marcela, Wahinuddin, Sulaiman, Lau, Ing Soo, Heselynn, Hussein, Nor-Shuhaila, Shahril, Gun, Suk Chyn, Eashwary, Mageswaran, Mohd-Shahrir, Mohamed Said, Ainon, Mohd Mokhtar, Azmillah, Rosman, Muhaini, Othman, Shahnaz, Murad, Alfredsson, Lars, Klareskog, Lars, Padyukov, Leonid

“…Fine-mapping of human leukocyte antigen (HLA) region for rheumatoid arthritis (RA) risk factors has identified several HLA alleles and its corresponding amino…”
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New insight on the Xq28 association with systemic sclerosis by Carmona, F David, Cénit, M Carmen, Diaz-Gallo, Lina-Marcela, Broen, Jasper C A, Simeón, Carmen P, Carreira, Patricia E, Callejas-Rubio, José-Luis, Fonollosa, Vicente, López-Longo, Francisco J, González-Gay, Miguel A, Hunzelmann, Nicolas, Riemekasten, Gabriela, Witte, Torsten, Kreuter, Alexander, Distler, Jörg H W, Madhok, Rajan, Shiels, Paul, van Laar, Jacob M, Schuerwegh, Annemie J, Vonk, Madelon C, Voskuyl, Alexandre E, Fonseca, Carmen, Denton, Christopher P, Herrick, Ariane, Worthington, Jane, Arnett, Frank C, Tan, Filemon K, Assassi, Shervin, Radstake, Timothy R D J, Mayes, Maureen D, Martín, Javier

“…To evaluate whether the systemic sclerosis (SSc)-associated IRAK1 non-synonymous single-nucleotide polymorphism rs1059702 is responsible for the Xq28…”
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Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study by Folkersen, Lasse, Brynedal, Boel, Diaz-Gallo, Lina Marcela, Ramsköld, Daniel, Shchetynsky, Klementy, Westerlind, Helga, Sundström, Yvonne, Schepis, Danika, Hensvold, Aase, Vivar, Nancy, Eloranta, Maija-Leena, Rönnblom, Lars, Brunak, Søren, Malmström, Vivianne, Catrina, Anca, Moerch, Ulrik Gw, Klareskog, Lars, Padyukov, Leonid, Berg, Louise

“…In rheumatoid arthritis (RA) several recent efforts have sought to discover means of predicting which patients would benefit from treatment. However, results…”
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Gene–gene interaction and RNA splicing profiles of MAP2K4 gene in rheumatoid arthritis by Shchetynsky, Klementy, Protsyuk, Darya, Ronninger, Marcus, Diaz-Gallo, Lina-Marcela, Klareskog, Lars, Padyukov, Leonid

“…Abstract We performed gene–gene interaction analysis, with HLA-DRB1 shared epitope (SE) alleles for 195 SNPs within immunologically important MAP2K, MAP3K and…”
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P13 Acquired ficolin-3 deficiency in patients with systemic lupus erythematosus by Lindelöf, Linnea, Rantapää-Dahlqvist, Solbritt, Lundtoft, Christian, Sandling, Johanna K, Leonard, Dag, Sayadi, Ahmed, Rönnblom, Lars, Enocsson, Helena, Sjöwall, Christopher, Jönsen, Andreas, Bengtsson, Anders A, Hong, Mun-Gwan, Diaz-Gallo, Lina-Marcela, Bianchi, Matteo, Kozyrev, Sergey V, Lindblad-Toh, Kerstin, Ekdahl, Kristina Nilsson, Nilsson, Bo, Gunnarsson, Iva, Svenungsson, Elisabet, Eriksson, Oskar

“…ObjectiveFicolin-3 is the main initiator of the lectin pathway of complement in humans. Case reports of ficolin-3 deficient patients have suggested that…”
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O16 pQTL analysis of ficolin-3 activity reveals a link between the lectin pathway of complement and hematological disease manifestations in systemic lupus erythematosus by Lindelöf, Linnea, Rantapää-Dahlqvist, Solbritt, Lundtoft, Christian, Sandling, Johanna K, Leonard, Dag, Sayadi, Ahmed, Rönnblom, Lars, Enocsson, Helena, Sjöwall, Christopher, Jönsen, Andreas, Bengtsson, Anders A, Hong, Mun-Gwan, Diaz-Gallo, Lina-Marcela, Bianchi, Matteo, Kozyrev, Sergey V, Lindblad-Toh, Kerstin, Ekdahl, Kristina Nilsson, Nilsson, Bo, Gunnarsson, Iva, Svenungsson, Elisabet, Eriksson, Oskar

“…ObjectiveThe complement system plays a central role in the pathogenesis of Systemic Lupus Erythematosus (SLE), but most studies have focused on the classical…”
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Meta-analysis of HLA-DRB1 and HLA-DQB1 polymorphisms in Latin American patients with systemic lupus erythematosus by Castaño-Rodríguez, Natalia, Diaz-Gallo, Lina-Marcela, Pineda-Tamayo, Ricardo, Rojas-Villarraga, Adriana, Anaya, Juan-Manuel

“…Abstract Objective To estimate the common effect size of HLA-DRB1 and -DQB1 alleles on systemic lupus erythematosus (SLE) susceptibility across Latin America…”
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