Search Results - "Diaz, Marietta"

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    Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing by Durban, Jordi, Juárez, Paula, Angulo, Yamileth, Lomonte, Bruno, Flores-Diaz, Marietta, Alape-Girón, Alberto, Sasa, Mahmood, Sanz, Libia, Gutiérrez, José M, Dopazo, Joaquín, Conesa, Ana, Calvete, Juan J

    Published in BMC genomics (23-05-2011)
    “…A long term research goal of venomics, of applied importance for improving current antivenom therapy, but also for drug discovery, is to understand the…”
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    Journal Article
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    NanI and NanJ Sialidases of Clostridium perfringens Are Not Essential for Virulence by Chiarezza, Martina, Lyras, Dena, Pidot, Sacha J, Flores-Díaz, Marietta, Awad, Milena M, Kennedy, Catherine L, Cordner, Leanne M, Phumoonna, Tongted, Poon, Rachael, Hughes, Meredith L, Emmins, John J, Alape-Girón, Alberto, Rood, Julian I

    Published in Infection and Immunity (01-10-2009)
    “…The essential toxin in Clostridium perfringens-mediated gas gangrene or clostridial myonecrosis is alpha-toxin, although other toxins and extracellular enzymes…”
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    Bacterial Sphingomyelinases and Phospholipases as Virulence Factors by Flores-Díaz, Marietta, Monturiol-Gross, Laura, Naylor, Claire, Alape-Girón, Alberto, Flieger, Antje

    Published in Microbiology and molecular biology reviews (01-09-2016)
    “…Bacterial sphingomyelinases and phospholipases are a heterogeneous group of esterases which are usually surface associated or secreted by a wide variety of…”
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    Biological models in multiple sclerosis by Sanabria‐Castro, Alfredo, Flores‐Díaz, Marietta, Alape‐Girón, Alberto

    Published in Journal of neuroscience research (01-03-2020)
    “…Considering the etiology of multiple sclerosis (MS) is still unknown, experimental models resembling specific aspects of this immune‐mediated demyelinating…”
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    Snake Venomics of the Lancehead Pitviper Bothrops asper: Geographic, Individual, and Ontogenetic Variations by Alape-Girón, Alberto, Sanz, Libia, Escolano, José, Flores-Díaz, Marietta, Madrigal, Marvin, Sasa, Mahmood, Calvete, Juan J

    Published in Journal of proteome research (01-08-2008)
    “…We report the comparative proteomic characterization of the venoms of adult and newborn specimens of the lancehead pitviper Bothrops asper from two…”
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    Bacterial phospholipases C with dual activity: phosphatidylcholinesterase and sphingomyelinase by Monturiol‐Gross, Laura, Villalta‐Romero, Fabian, Flores‐Díaz, Marietta, Alape‐Girón, Alberto

    Published in FEBS open bio (01-12-2021)
    “…Bacterial phospholipases and sphingomyelinases are lipolytic esterases that are structurally and evolutionarily heterogeneous. These enzymes play crucial roles…”
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    Clostridium perfringens phospholipase C, an archetypal bacterial virulence factor, induces the formation of extracellular traps by human neutrophils by Badilla-Vargas, Lisa, Pereira, Reynaldo, Molina-Mora, José Arturo, Alape-Girón, Alberto, Flores-Díaz, Marietta

    “…Neutrophil extracellular traps (NETs) are networks of DNA and various microbicidal proteins released to kill invading microorganisms and prevent their…”
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    Deficient Skeletal Muscle Regeneration after Injury Induced by a Clostridium perfringens Strain Associated with Gas Gangrene by Zúñiga-Pereira, Ana Mariel, Santamaría, Carlos, Gutierrez, José María, Alape-Girón, Alberto, Flores-Díaz, Marietta

    Published in Infection and immunity (01-08-2019)
    “…Gas gangrene, or clostridial myonecrosis, is usually caused by and may occur spontaneously in association with diabetes mellitus, peripheral vascular disease,…”
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    Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming by Gutiérrez, José María, Lomonte, Bruno, León, Guillermo, Alape-Girón, Alberto, Flores-Díaz, Marietta, Sanz, Libia, Angulo, Yamileth, Calvete, Juan J.

    Published in Journal of proteomics (06-03-2009)
    “…Snakebite envenoming represents a neglected tropical disease that has a heavy public health impact, particularly in Asia, Africa and Latin America. A global…”
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    Clostridium perfringens phospholipase C induced ROS production and cytotoxicity require PKC, MEK1 and NFκB activation by Monturiol-Gross, Laura, Flores-Díaz, Marietta, Pineda-Padilla, Maria Jose, Castro-Castro, Ana Cristina, Alape-Giron, Alberto

    Published in PloS one (2014)
    “…Clostridium perfringens phospholipase C (CpPLC), also called α-toxin, is the most toxic extracellular enzyme produced by this bacteria and is essential for…”
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    Internalization of Clostridium perfringens α‐toxin leads to ERK activation and is involved on its cytotoxic effect by Monturiol‐Gross, Laura, Flores‐Díaz, Marietta, Campos‐Rodríguez, Diana, Mora, Rodrigo, Rodríguez‐Vega, Mariela, Marks, David L., Alape‐Girón, Alberto

    Published in Cellular microbiology (01-04-2014)
    “…Summary Clostridium perfringens phospholipase C (CpPLC), also called α‐toxin, plays a key role in the pathogenesis of gas gangrene. CpPLC may lead to cell…”
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    Journal Article
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