Search Results - "Diaz, Fanny"
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Identification of NADPH oxidase as a key mediator in the post‐ischemia‐induced sequestration and degradation of the GluA2 AMPA receptor subunit
Published in Journal of neurochemistry (01-03-2015)“…A hallmark of ischemic/reperfusion injury is a change in subunit composition of synaptic 2‐amino‐3‐(3‐hydroxy‐5‐methylisoazol‐4‐yl)propionic acid receptors…”
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2,3‐Dihydro‐1‐Benzofuran Derivatives as a Series of Potent Selective Cannabinoid Receptor 2 Agonists: Design, Synthesis, and Binding Mode Prediction through Ligand‐Steered Modeling
Published in ChemMedChem (01-10-2009)“…We recently discovered and reported a series of N‐alkyl‐isatin acylhydrazone derivatives that are potent cannabinoid receptor 2 (CB2) agonists. In an effort to…”
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In vivo efficacy of enabling formulations based on hydroxypropyl-β-cyclodextrins, micellar preparation, and liposomes for the lipophilic cannabinoid CB2 agonist, MDA7
Published in Daru (01-02-2013)“…Enabling formulations based on hydroxypropyl-β-cyclodextrins (HPβCD), micellar preparation, and liposomes have been designed to deliver the racemic mixture of…”
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Liposomal Encapsulated FSC231, a PICK1 Inhibitor, Prevents the Ischemia/Reperfusion-Induced Degradation of GluA2-Containing AMPA Receptors
Published in Pharmaceutics (30-04-2021)“…Strokes remain one of the leading causes of disability within the United States. Despite an enormous amount of research effort within the scientific community,…”
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Pharmacological Characterization of a Novel Cannabinoid Ligand, MDA19, for Treatment of Neuropathic Pain
Published in Anesthesia and analgesia (01-07-2010)“…Cannabinoid receptor 2 (CB2) agonists have recently gained attention as potential therapeutic targets in the management of neuropathic pain. In this study, we…”
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Multidisciplinary analyses of partial human remains discovered in the Caribbean Sea (Venezuela)
Published in Australian journal of forensic sciences (01-05-2024)“…In March 2022, human remains were discovered submerged 15 metres underwater, near Cubagua Island, Venezuela. The remains were intricately entangled and secured…”
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Essential oils, a response to unpleasant odors in resuscitation of burn victims
Published in Soins; la revue de référence infirmière (01-03-2022)“…In burn units, odor is often underestimated or trivialized in relation to the critical context of the patients. However, their care is part of a concern for…”
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Development and Characterization of Novel and Selective Inhibitors of Cytochrome P450 CYP26A1, the Human Liver Retinoic Acid Hydroxylase
Published in Journal of medicinal chemistry (24-03-2016)“…Cytochrome P450 CYP26 enzymes are responsible for all-trans-retinoic acid (atRA) clearance. Inhibition of CYP26 enzymes will increase endogenous atRA…”
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Mastering tricyclic ring systems for desirable functional cannabinoid activity
Published in European journal of medicinal chemistry (01-11-2013)“…There is growing interest in using cannabinoid receptor 2 (CB2) agonists for the treatment of neuropathic pain and other indications. In continuation of our…”
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Design and Synthesis of a Novel Series of N-Alkyl Isatin Acylhydrazone Derivatives that Act as Selective Cannabinoid Receptor 2 Agonists for the Treatment of Neuropathic Pain
Published in Journal of medicinal chemistry (28-08-2008)“…There is growing interest in using cannabinoid receptor 2 (CB2) agonists for the treatment of neuropathic pain. We have synthesized a novel series of N-alkyl…”
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6-Methoxy-N-alkyl Isatin Acylhydrazone Derivatives as a Novel Series of Potent Selective Cannabinoid Receptor 2 Inverse Agonists: Design, Synthesis, and Binding Mode Prediction
Published in Journal of medicinal chemistry (22-01-2009)“…Recently, we discovered and reported a series of N-alkyl isatin acylhydrazone derivatives that are potent CB2 agonists. Here, we describe a novel series of…”
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Pharmacological Characterization of a Novel Cannabinoid Ligand, MDA19, for Treatment of Neuropathic Pair
Published in Anesthesia and analgesia (2010)Get full text
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Otredad y Relaciones Internacionales: ¿una episteme trascendente a las ciencias sociales?
Published in Política, globalidad y ciudadanía (30-12-2023)“…El presente trabajo tuvo como fin analizar en qué medida la disciplina de las Relaciones Internacionales, merced a su ontológica necesidad de estudiar a la…”
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Saber objetivo sobre la subjetividad en psiquiatría, desde la filosofía y el psicoanálisis
Published in Revista de la Asociación Española de Neuropsiquiatría (01-06-2013)Get full text
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Mortalidad fetal, frecuencia y factores de riesgo, departamento de Antioquia, noviembre de 1997 a junio de 1998
Published in C.E.S. medicina (1999)“…Utilizando las bases de datos del Departamento Administrativo Nacional de Estadística (DANE) de nacimientos y defunciones para Antioquia entre Noviembre de…”
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