Search Results - "Diaz, Bianca"
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CRISPR in cancer biology and therapy
Published in Nature reviews. Cancer (01-05-2022)“…Over the past decade, CRISPR has become as much a verb as it is an acronym, transforming biomedical research and providing entirely new approaches for…”
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Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants
Published in Nature biotechnology (01-06-2022)“…Base editing can be applied to characterize single nucleotide variants of unknown function, yet defining effective combinations of single guide RNAs (sgRNAs)…”
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Tankyrase inhibition sensitizes cells to CDK4 blockade
Published in PloS one (31-12-2019)“…Tankyrase (TNKS) 1/2 are positive regulators of WNT signaling by controlling the activity of the ß-catenin destruction complex. TNKS inhibitors provide an…”
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Generation of precision preclinical cancer models using regulated in vivo base editing
Published in Nature biotechnology (01-03-2024)“…Although single-nucleotide variants (SNVs) make up the majority of cancer-associated genetic changes and have been comprehensively catalogued, little is known…”
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Development and Validation of an ICU Delirium Playbook for Provider Education
Published in Critical care explorations (01-07-2023)“…Although delirium detection and prevention practices are recommended in critical care guidelines, there remains a persistent lack of effective delirium…”
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Pressure and stretch differentially affect proliferation of renal proximal tubular cells
Published in Physiological reports (01-09-2017)“…Renal obstruction is frequently found in adults and children. Mechanical stimuli, including pressure and stretch in the obstructed kidney, contribute to…”
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Spanish Translation and Cultural Adaptation of the Intensive Care Unit Delirium Playbook
Published in ATS scholar (01-06-2024)“…A lack of high-quality provider education hinders the delivery of standard-of-care delirium detection and prevention practices in the intensive care unit…”
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GO: a functional reporter system to identify and enrich base editing activity
Published in Nucleic acids research (06-04-2020)“…Abstract Base editing (BE) is a powerful tool for engineering single nucleotide variants (SNVs) and has been used to create targeted mutations in cell lines,…”
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Abstract PHA05: Strategies to improve engineering cancer-associated SNVs with base editing
Published in Cancer research (Chicago, Ill.) (01-06-2020)“…Abstract Base editing (BE) is a powerful tool for engineering single-nucleotide variants (SNVs) and has been used to create targeted mutations in cell lines,…”
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REDE DE ATENÇÃO E ENSINO DA GERÊNCIA GLÓRIA-CRUZEIRO-CRISTAL NO MUNICÍPIO DE PORTO ALEGRE/RS
Published in Saberes Plurais (Online) (28-12-2019)“…Este número apresenta informações sobre a Rede de Atenção e Ensino da Gerência Distrital Glória-Cruzeiro-Cristal, que se originou do projeto de pesquisa…”
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REDE DE ATENÇÃO E ENSINO DA SAÚDE BUCAL NA GERÊNCIA DISTRITAL NORTE-HUMAITÁ-NAVEGANTES-ILHAS, PORTO ALEGRE/RS
Published in Saberes Plurais (Online) (28-12-2019)“…Este número do Boletim Informativo Saberes Plurais apresenta informações sobre a Rede de Atenção e Ensino da Saúde Bucal na Gerência…”
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REDE DE ATENÇÃO E ENSINO DA SAÚDE BUCAL NA GERÊNCIA DISTRITAL PARTENON-LOMBA DO PINHEIRO, PORTO ALEGRE/RS
Published in Saberes Plurais (Online) (28-12-2019)“…Este número do Boletim Informativo Saberes Plurais apresenta informações sobre a Rede de Atenção e Ensino da Saúde Bucal na Gerência Partenon/Lomba do Pinheiro…”
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REDE DE ATENÇÃO E ENSINO DA GERÊNCIA DISTRITAL SUL-CENTRO-SUL NO MUNICÍPIO DE PORTO ALEGRE/RS
Published in Saberes Plurais (Online) (28-12-2019)“…Este número apresenta informações sobre a “Rede de Atenção e Ensino da Gerência Distrital Sul-Centro-Sul (GD SCS)”, que se originou do projeto de pesquisa…”
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REDE DE ATENÇÃO E ENSINO DA SAÚDE BUCAL NA GERÊNCIA DISTRITAL NORTE/EIXO-BALTAZAR, EM PORTO ALEGRE/RS
Published in Saberes Plurais (Online) (28-12-2019)“…Este número do Boletim Informativo Saberes Plurais apresenta informações sobre a Rede de Atenção e Ensino da Saúde Bucal na Gerência Norte/Eixo-Baltazar do…”
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REDE DE ATENÇÃO E ENSINO DA GERÊNCIA CENTRO NO MUNICÍPIO DE PORTO ALEGRE/RS
Published in Saberes Plurais (Online) (28-12-2019)“…Este número do Boletim Informativo Saberes Plurais apresenta informações sobre a Rede de Atenção e Ensino da Gerência Distrital Centro, que se originou do…”
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REDE DE ATENÇÃO E ENSINO DA GERÊNCIA RESTINGA-EXTREMO SUL NO MUNICÍPIO DE PORTO ALEGRE/RS
Published in Saberes Plurais (Online) (28-12-2019)“…Este número do Boletim Informativo Saberes Plurais apresenta informações sobre a Rede de Atenção e Ensino da Gerência Distrital Restinga-Extremo Sul, que se…”
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REDE DE ATENÇÃO E ENSINO DA SAÚDE BUCAL NA GERÊNCIA DISTRITAL LESTE-NORDESTE, EM PORTO ALEGRE/RS
Published in Saberes Plurais (Online) (28-12-2019)“…Este número do Boletim Informativo Saberes Plurais apresenta informações sobre a Rede de Atenção e Ensino da Saúde Bucal na Gerência Leste-Nordeste do…”
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Identification of Cancer Drivers at CTCF Insulators in 1,962 Whole Genomes
Published in Cell systems (22-05-2019)“…Recent studies have shown that mutations at non-coding elements, such as promoters and enhancers, can act as cancer drivers. However, an important class of…”
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Pressure applied in vitro increases proliferation of renal proximal tubular cells (1180.7)
Published in The FASEB journal (01-04-2014)“…Increased pressure in the kidney is a common finding in kidneys with obstructed ureters [UO]. In animal models of UO, increased cellular proliferation may…”
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