Search Results - "Diaz, Alexandre P."
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NLRP3 inflammasome-driven pathways in depression: Clinical and preclinical findings
Published in Brain, behavior, and immunity (01-08-2017)“…Highlights • Chronic stress activates NLRP3 complex in rodent brain. • NLRP3 is activated in peripheral blood mononuclear cells of patients with MDD. •…”
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The kynurenine pathway in major depressive disorder, bipolar disorder, and schizophrenia: a meta-analysis of 101 studies
Published in Molecular psychiatry (01-08-2021)“…The importance of tryptophan as a precursor for neuroactive compounds has long been acknowledged. The metabolism of tryptophan along the kynurenine pathway and…”
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3
Prevalence of depression in COPD: A systematic review and meta-analysis of controlled studies
Published in Respiratory medicine (01-08-2016)“…Abstract Background Depression is frequently reported in association with COPD. However, the prevalence of depression in these patients ranges largely. This…”
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Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings
Published in Revista brasileira de psiquiatria (01-09-2020)“…Bipolar disorder (BD) is a chronic mental illness characterized by changes in mood that alternate between mania and hypomania or between depression and mixed…”
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Treatment-resistant bipolar depression: concepts and challenges for novel interventions
Published in Revista brasileira de psiquiatria (01-03-2022)“…Treatment-resistant bipolar depression (TRBD) has been reported in about one-quarter of patients with bipolar disorders, and few interventions have shown clear…”
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Neurobiology of COVID-19: how can the virus affect the brain?
Published in Revista brasileira de psiquiatria (01-11-2021)“…Severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) causes the coronavirus disease 2019 (COVID-19), which has been declared a public health…”
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Social cognition and suicide-related behaviors in depression: a cross-sectional, exploratory study
Published in Revista brasileira de psiquiatria (24-10-2022)“…To explore the association between social cognition and previous suicide attempts and non-suicidal self-injurious behavior in adults with unipolar depressive…”
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Brazilian Psychiatric Association guidelines for the management of suicidal behavior. Part 1. Risk factors, protective factors, and assessment
Published in Revista brasileira de psiquiatria (01-09-2021)“…Suicide is a global public health problem that causes the loss of more than 800,000 lives each year, principally among young people. In Brazil, the average…”
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A narrative review on invasive brain stimulation for treatment-resistant depression
Published in Revista brasileira de psiquiatria (01-05-2022)“…While most patients with depression respond to pharmacotherapy and psychotherapy, about one-third will present treatment resistance to these interventions. For…”
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Return to work after severe traumatic brain injury: further investigation of the role of personality changes
Published in Revista brasileira de psiquiatria (01-05-2021)Get full text
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Brazilian Psychiatric Association guidelines for the management of suicidal behavior. Part 2. Screening, intervention, and prevention
Published in Revista brasileira de psiquiatria (01-09-2021)“…This article continues our presentation of the Brazilian Psychiatric Association guidelines for the management of patients with suicidal behavior, with a focus…”
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Difficulties in activities of daily living are associated with stigma in patients with Parkinson's disease who are candidates for deep brain stimulation
Published in Revista brasileira de psiquiatria (01-04-2020)“…Parkinson's disease (PD) is often accompanied by stigma, which could contribute to a worse prognosis. The objective of this study is to identify the variables…”
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At-risk drinking and current cannabis use among medical students: a multivariable analysis of the role of personality traits
Published in Revista brasileira de psiquiatria (01-04-2020)“…To explore the role of personality traits in at-risk drinking and current cannabis use among medical students. This cross-sectional study evaluated 707 medical…”
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Brazilian guidelines for the management of psychomotor agitation. Part 1. Non-pharmacological approach
Published in Revista brasileira de psiquiatria (01-03-2019)“…To present the essential guidelines for non-pharmacological management of patients with psychomotor agitation in Brazil. These guidelines were developed based…”
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Stigma toward individuals with mental disorders among Brazilian psychiatrists: a latent class analysis
Published in Revista brasileira de psiquiatria (01-05-2021)“…OBJECTIVEThe stigma toward individuals with mental disorders is highly prevalent, not only in the general population but among health care providers as well…”
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Brazilian guidelines for the management of psychomotor agitation. Part 2. Pharmacological approach
Published in Revista brasileira de psiquiatria (01-07-2019)“…To present the essential guidelines for pharmacological management of patients with psychomotor agitation in Brazil. This is a systematic review of articles…”
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Cross-cultural adaptation and psychometric evaluation of the Brazilian version of the Temporal Experience of Pleasure Scale (TEPS-Br)
Published in Trends in psychiatry and psychotherapy (01-01-2022)“…Anhedonia is a critical symptom of major depressive disorder that is defined as the reduced ability to experience pleasure. The Temporal Experience of Pleasure…”
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Dysregulation of mitochondrial dynamics, mitophagy and apoptosis in major depressive disorder: Does inflammation play a role?
Published in Molecular psychiatry (01-02-2022)“…Recent studies have suggested that mitochondrial dysfunction and dysregulated neuroinflammatory pathways are involved in the pathophysiology of major…”
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Personality changes and return to work after severe traumatic brain injury: a prospective study
Published in Revista brasileira de psiquiatria (01-09-2014)“…To evaluate predictors of non-return to work (nRTW) among social, demographic, clinical, and psychiatric variables after severe traumatic brain injury (TBI) in…”
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Validity and screening properties of three depression rating scales in a prospective sample of patients with severe traumatic brain injury
Published in Revista brasileira de psiquiatria (01-09-2014)“…To evaluate the validity and utility of the Hamilton Rating Scale for Depression (HAM-D), Beck Depression Inventory (BDI), and Hospital Anxiety and Depression…”
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