Search Results - "Diavatopoulos, Dimitri A"
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Host and Environmental Factors Influencing Individual Human Cytokine Responses
Published in Cell (03-11-2016)“…Differences in susceptibility to immune-mediated diseases are determined by variability in immune responses. In three studies within the Human Functional…”
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BCG Vaccination Induces Long-Term Functional Reprogramming of Human Neutrophils
Published in Cell reports (Cambridge) (17-11-2020)“…The tuberculosis vaccine bacillus Calmette-Guérin (BCG) protects against some heterologous infections, probably via induction of non-specific innate immune…”
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3
SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms
Published in Nature communications (23-09-2021)“…Although serological studies have shown that antibodies against SARS-CoV-2 play an important role in protection against (re)infection, the dynamics of mucosal…”
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Antiviral responses induced by Tdap-IPV vaccination are associated with persistent humoral immunity to Bordetella pertussis
Published in Nature communications (08-03-2024)“…Many countries continue to experience pertussis epidemics despite widespread vaccination. Waning protection after booster vaccination has highlighted the need…”
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Effect of FHA and Prn on Bordetella pertussis colonization of mice is dependent on vaccine type and anatomical site
Published in PloS one (21-08-2020)“…Bordetella pertussis vaccine escape mutants that lack expression of the pertussis antigen pertactin (Prn) have emerged in vaccinated populations in the last…”
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Prior exposure to B. pertussis shapes the mucosal antibody response to acellular pertussis booster vaccination
Published in Nature communications (02-12-2022)“…Bordetella pertussis (Bp), the causative agent of pertussis, continues to circulate despite widespread vaccination programs. An important question is whether…”
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Proteomics-identified Bvg-activated autotransporters protect against bordetella pertussis in a mouse model
Published in PloS one (18-08-2014)“…Pertussis is a highly infectious respiratory disease of humans caused by the bacterium Bordetella pertussis. Despite high vaccination coverage, pertussis has…”
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A semi high-throughput whole blood-based flow cytometry assay to detect and monitor Bordetella pertussis -specific Th1, Th2 and Th17 responses
Published in Frontiers in immunology (06-02-2023)“…The characterization of (Bp) antigen-specific CD4 T cell cytokine responses should be included in the evaluation of immunogenicity of pertussis vaccines but is…”
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SARS-CoV-2 RNA in exhaled air of hospitalized COVID-19 patients
Published in Scientific reports (30-05-2022)“…Knowledge about contagiousness is key to accurate management of hospitalized COVID-19 patients. Epidemiological studies suggest that in addition to…”
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Bordetella pertussis, the causative agent of whooping cough, evolved from a distinct, human-associated lineage of B. bronchiseptica
Published in PLoS pathogens (01-12-2005)“…Bordetella pertussis, B. bronchiseptica, B. parapertussis(hu), and B. parapertussis(ov) are closely related respiratory pathogens that infect mammalian…”
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Increased nasopharyngeal bacterial titers and local inflammation facilitate transmission of Streptococcus pneumoniae
Published in mBio (2012)“…The transmission of the bacterium Streptococcus pneumoniae (the pneumococcus) marks the first step toward disease development. To date, our ability to prevent…”
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Antibodies Mediate Formation of Neutrophil Extracellular Traps in the Middle Ear and Facilitate Secondary Pneumococcal Otitis Media
Published in Infection and Immunity (01-01-2014)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A novel flow cytometry-based assay for the quantification of antibody-dependent pneumococcal agglutination
Published in PloS one (13-03-2017)“…The respiratory pathogen Streptococcus pneumoniae is a major cause of diseases such as otitis media, pneumonia, sepsis and meningitis. The first step towards…”
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Influenza-Induced Inflammation Drives Pneumococcal Otitis Media
Published in Infection and Immunity (01-03-2013)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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15
Bacillus Calmette-Guérin-Induced Trained Immunity Is Not Protective for Experimental Influenza A/Anhui/1/2013 (H7N9) Infection in Mice
Published in Frontiers in immunology (30-04-2018)“…Avian influenza A of the subtype H7N9 has been responsible for almost 1,600 confirmed human infections and more than 600 deaths since its first outbreak in…”
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Modification of innate immune responses to Bordetella pertussis in babies from pertussis vaccinated pregnancies
Published in EBioMedicine (01-10-2021)“…Tetanus, diphtheria, acellular pertussis, inactivated polio (Tdap-IPV) vaccines administered during pregnancy protect young infants from Bordetella pertussis…”
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Mucosal immunity to severe acute respiratory syndrome coronavirus 2 infection
Published in Current opinion in infectious diseases (01-06-2021)“…Despite its crucial role in protection against viral infections, mucosal immunity has been largely understudied in the context of coronavirus disease 2019…”
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Responses to an acellular pertussis booster vaccination in children, adolescents, and young and older adults: A collaborative study in Finland, the Netherlands, and the United Kingdom
Published in EBioMedicine (01-03-2021)“…Pertussis can lead to serious disease and even death in infants. Older adults are more vulnerable to complications as well. In high-income countries, acellular…”
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Exploring metal availability in the natural niche of Streptococcus pneumoniae to discover potential vaccine antigens
Published in Virulence (31-12-2020)“…Nasopharyngeal colonization by Streptococcus pneumoniae is a prerequisite for pneumococcal transmission and disease. Current vaccines protect only against…”
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Preliminary evidence of localizing CD8+ T-cell responses in COVID-19 patients with PET imaging
Published in Frontiers in medicine (15-05-2024)“…The upper respiratory tract (URT) is the entry site for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), from where it further disseminates. Early…”
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