Search Results - "Dias, Waldely"
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In vitro Evidence of Human Immune Responsiveness Shows the Improved Potential of a Recombinant BCG Strain for Bladder Cancer Treatment
Published in Frontiers in immunology (26-06-2019)“…The live attenuated mycobacterial strain BCG, in use as vaccine against tuberculosis, is considered the gold standard for primary therapy of carcinoma of the…”
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2
GMP-grade pneumococcal whole-cell vaccine injected subcutaneously protects mice from nasopharyngeal colonization and fatal aspiration-sepsis
Published in Vaccine (03-11-2010)“…Abstract Mucosal immunization with a killed whole-cell pneumococcal vaccine, given with enterotoxin-related adjuvants, has been shown to confer multi-serotype…”
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3
Development of a whole cell pneumococcal vaccine: BPL inactivation, cGMP production, and stability
Published in Vaccine (19-02-2014)“…Highlights • The consistency of the production process was shown in 60-L bioreactors. • Cell recovery by tangential filtration was 92 ± 13%. • Conditions for…”
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Economical value of vaccines for the developing countries--the case of Instituto Butantan, a public institution in Brazil
Published in PLoS neglected tropical diseases (01-11-2011)“… The companies are understandably reluctant to create competitors with knowledge and capabilities in the most up-to-date production methods and most advanced…”
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Construction of an unmarked recombinant BCG expressing a pertussis antigen by auxotrophic complementation: Protection against Bordetella pertussis challenge in neonates
Published in Vaccine (09-12-2009)“…Abstract Mycobacterium bovis BCG has long been investigated as a candidate for heterologous antigen presentation. We have previously described an…”
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6
An improved whole cell pertussis vaccine with reduced content of endotoxin
Published in Human vaccines & immunotherapeutics (01-02-2013)“…An improved whole cell pertussis vaccine, designated as Plow, which is low in endotoxicity due to a chemical extraction of lipo-oligosaccharide (LOS) from the…”
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Neonatal immunization with a single dose of recombinant BCG expressing subunit S1 from pertussis toxin induces complete protection against Bordetella pertussis intracerebral challenge
Published in Microbes and infection (01-02-2008)“…The currently used pertussis vaccines are highly efficacious; however, neonates are susceptible to whooping cough up to the sixth month. In agreement,…”
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Recombinant Mycobacterium bovis BCG Expressing the Sm14 Antigen of Schistosoma mansoni Protects Mice from Cercarial Challenge
Published in Infection and Immunity (01-06-2004)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Analysis of Serum Cross-Reactivity and Cross-Protection Elicited by Immunization with DNA Vaccines against Streptococcus pneumoniae Expressing PspA Fragments from Different Clades
Published in Infection and Immunity (01-09-2002)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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10
ACELLULAR AND LOW PERTUSSIS VACCINES: ADVERSE EVENTS AND THE ROLE OF MUTATIONS
Published in Revista do Instituto de Medicina Tropical de São Paulo (01-05-2009)“…to discuss the current PAHO recommendation that does not support the substitution of traditional cellular DTP vaccine by acellular DTP, and the role of…”
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Sm14 of Schistosoma mansoni in Fusion with Tetanus Toxin Fragment C Induces Immunoprotection against Tetanus and Schistosomiasis in Mice
Published in Infection and Immunity (01-10-2004)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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12
Expression and characterization of cholera toxin B—pneumococcal surface adhesin A fusion protein in Escherichia coli: ability of CTB-PsaA to induce humoral immune response in mice
Published in Biochemical and biophysical research communications (13-08-2004)“…Cholera toxin B subunit (CTB) is responsible for CT holotoxin binding to the cell and has been described as a mucosal adjuvant for vaccines. In this work, the…”
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13
Immunogenicity of a Whole-Cell Pertussis Vaccine with Low Lipopolysaccharide Content in Infants
Published in Clinical and Vaccine Immunology (01-04-2009)“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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14
Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C
Published in Vaccine (26-01-2004)“…In order to develop a combined recombinant Mycobacterium bovis BCG (rBCG) vaccine against diphtheria, pertussis and tetanus (DPT), we have constructed…”
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15
PsaA (pneumococcal surface adhesin A) and PspA (pneumococcal surface protein A) DNA vaccines induce humoral and cellular immune responses against Streptococcus pneumoniae
Published in Vaccine (12-12-2001)“…Streptococcus pneumoniae is one of the most important human pathogens and improvement of the currently used polysaccharide vaccines is being pursued. We…”
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Induction of Neutralizing Antibodies against Diphtheria Toxin by Priming with Recombinant Mycobacterium bovis BCG Expressing CRM197, a Mutant Diphtheria Toxin
Published in Infection and Immunity (01-02-2001)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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17
Optimization of the conjugation method for a serogroup B/C meningococcal vaccine
Published in Biotechnology and applied biochemistry (01-11-2006)“…A conjugate meningococcal vaccine against serogroup B/C consisting of capsular PS (polysaccharide) from serogroup C conjugated to OMV (outer membrane vesicle)…”
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r-Sm14 - pRSETA Efficacy in Experimental Animals
Published in Memórias do Instituto Oswaldo Cruz (01-01-2001)“…Previous studies carried out with Sm14 in experimental vaccination against Schistosoma mansoni or Fasciola hepatica infections were performed with recombinant…”
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Mycobacterial codon optimization of the gene encoding the Sm14 antigen of Schistosoma mansoni in recombinant Mycobacterium bovis Bacille Calmette-Guérin enhances protein expression but not protection against cercarial challenge in mice
Published in FEMS immunology and medical microbiology (01-10-2006)“…Abstract A mycobacterial codon-optimized gene encoding the Sm14 antigen of Schistosoma mansoni was generated using oligonucleotide assembly. This synthetic…”
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Adjuvant can improve protection induced by OMV vaccine against Neisseria meningitidis serogroups B/C in neonatal mice
Published in FEMS immunology and medical microbiology (01-07-2004)“…Meningococcal outer membrane vesicle (OMV) vaccines are weak antigens in infants. This study aimed at investigating alternative adjuvants for induction of…”
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