Search Results - "Dias, Suelen"

The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle by Ricciardi, Simona, Guarino, Andrea Maria, Giaquinto, Laura, Polishchuk, Elena V., Santoro, Michele, Di Tullio, Giuseppe, Wilson, Cathal, Panariello, Francesco, Soares, Vinicius C., Dias, Suelen S. G., Santos, Julia C., Souza, Thiago M. L., Fusco, Giovanna, Viscardi, Maurizio, Brandi, Sergio, Bozza, Patrícia T., Polishchuk, Roman S., Venditti, Rossella, De Matteis, Maria Antonietta

“…SARS-CoV-2, like other coronaviruses, builds a membrane-bound replication organelle to enable RNA replication 1 . The SARS-CoV-2 replication organelle is…”
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SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes by Ferreira, André C., Soares, Vinicius Cardoso, de Azevedo-Quintanilha, Isaclaudia G., Dias, Suelen da Silva Gomes, Fintelman-Rodrigues, Natalia, Sacramento, Carolina Q., Mattos, Mayara, de Freitas, Caroline S., Temerozo, Jairo R., Teixeira, Lívia, Damaceno Hottz, Eugenio, Barreto, Ester A., Pão, Camila R. R., Palhinha, Lohanna, Miranda, Milene, Bou-Habib, Dumith Chequer, Bozza, Fernando A., Bozza, Patrícia T., Souza, Thiago Moreno L.

“…Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with leukopenia and uncontrolled inflammatory response in…”
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SARS-CoV-2 Proteins Bind to Hemoglobin and Its Metabolites by Lechuga, Guilherme C, Souza-Silva, Franklin, Sacramento, Carolina Q, Trugilho, Monique R O, Valente, Richard H, Napoleão-Pêgo, Paloma, Dias, Suelen S G, Fintelman-Rodrigues, Natalia, Temerozo, Jairo R, Carels, Nicolas, Alves, Carlos R, Pereira, Mirian C S, Provance, Jr, David W, Souza, Thiago M L, De-Simone, Salvatore G

“…(1) Background: coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been linked to hematological…”
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Agathisflavone, a natural biflavonoid that inhibits SARS-CoV-2 replication by targeting its proteases by Chaves, Otávio Augusto, Lima, Carlyle Ribeiro, Fintelman-Rodrigues, Natalia, Sacramento, Carolina Q., de Freitas, Caroline S., Vazquez, Leonardo, Temerozo, Jairo R., Rocha, Marco E.N., Dias, Suelen S.G., Carels, Nicolas, Bozza, Patrícia T., Castro-Faria-Neto, Hugo Caire, Souza, Thiago Moreno L.

“…Despite the fast development of vaccines, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) still circulates through variants of concern (VoC)…”
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Adipose-derived Mesenchymal Stromal Cells Modulate Lipid Metabolism and Lipid Droplet Biogenesis via AKT/mTOR –PPARγ Signalling in Macrophages by Souza-Moreira, Luciana, Soares, Vinicius Cardoso, Dias, Suelen da Silva Gomes, Bozza, Patricia T.

“…Mesenchymal stromal cells (MSCs) are a potential therapy for many chronic inflammatory diseases due to their regenerative, immunologic and anti-inflammatory…”
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Atazanavir, Alone or in Combination with Ritonavir, Inhibits SARS-CoV-2 Replication and Proinflammatory Cytokine Production by Fintelman-Rodrigues, Natalia, Sacramento, Carolina Q, Ribeiro Lima, Carlyle, Souza da Silva, Franklin, Ferreira, André C, Mattos, Mayara, de Freitas, Caroline S, Cardoso Soares, Vinicius, da Silva Gomes Dias, Suelen, Temerozo, Jairo R, Miranda, Milene D, Matos, Aline R, Bozza, Fernando A, Carels, Nicolas, Alves, Carlos Roberto, Siqueira, Marilda M, Bozza, Patrícia T, Souza, Thiago Moreno L

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is already responsible for far more deaths than previous pathogenic coronaviruses (CoVs) from 2002…”
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The Role of Pyrazolopyridine Derivatives on Different Steps of Herpes Simplex Virus Type-1 In Vitro Replicative Cycle by Miranda, Milene D., Chaves, Otávio Augusto, Rosa, Alice S., Azevedo, Alexandre R., Pinheiro, Luiz Carlos da Silva, Soares, Vinicius C., Dias, Suelen S. G., Abrantes, Juliana L., Bernardino, Alice Maria R., Paixão, Izabel C. P., Souza, Thiago Moreno L., Fontes, Carlos Frederico L.

“…Herpes simplex virus type-1 (HSV-1) infection causes several disorders, and acyclovir is used as a reference compound. However, resistant strains are commonly…”
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Platelet-monocyte interaction amplifies thromboinflammation through tissue factor signaling in COVID-19 by Hottz, Eugenio D., Martins-Gonçalves, Remy, Palhinha, Lohanna, Azevedo-Quintanilha, Isaclaudia G., de Campos, Mariana M., Sacramento, Carolina Q., Temerozo, Jairo R., Soares, Vinicius Cardoso, Dias, Suelen S. Gomes, Teixeira, Lívia, Castro, Ícaro, Righy, Cassia, Souza, Thiago Moreno L., Kurtz, Pedro, Andrade, Bruno B., Nakaya, Helder I., Monteiro, Robson Q., Bozza, Fernando A., Bozza, Patrícia T.

“…Accumulating evidence into the pathogenesis of COVID-19 highlights a hypercoagulability state with high risk of life-threatening thromboembolic complications…”
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VIP plasma levels associate with survival in severe COVID‐19 patients, correlating with protective effects in SARS‐CoV‐2‐infected cells by Temerozo, Jairo R., Sacramento, Carolina Q., Fintelman‐Rodrigues, Natalia, Pão, Camila R. R., Freitas, Caroline S., Dias, Suelen Silva Gomes, Ferreira, André C., Mattos, Mayara, Soares, Vinicius Cardoso, Teixeira, Lívia, Azevedo‐Quintanilha, Isaclaudia G., Hottz, Eugenio D., Kurtz, Pedro, Bozza, Fernando A., Bozza, Patrícia T., Souza, Thiago Moreno L., Bou‐Habib, Dumith Chequer

“…Infection by SARS‐CoV‐2 may elicit uncontrolled and damaging inflammatory responses. Thus, it is critical to identify compounds able to inhibit virus…”
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SARS-CoV-2: Ultrastructural Characterization of Morphogenesis in an In Vitro System by Barreto-Vieira, Debora Ferreira, da Silva, Marcos Alexandre Nunes, de Almeida, Ana Luisa Teixeira, Rasinhas, Arthur da Costa, Monteiro, Maria Eduarda, Miranda, Milene Dias, Motta, Fernando Couto, Siqueira, Marilda M, Girard-Dias, Wendell, Archanjo, Bráulio Soares, Bozza, Patricia T, L Souza, Thiago Moreno, Gomes Dias, Suelen Silva, Soares, Vinicius Cardoso, Barth, Ortrud Monika

“…The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has impacted public health and the world economy and fueled a worldwide…”
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Platelet proteome reveals features of cell death, antiviral response and viral replication in covid-19 by Trugilho, Monique R. O., Azevedo-Quintanilha, Isaclaudia G., Gesto, João S. M., Moraes, Emilly Caroline S., Mandacaru, Samuel C., Campos, Mariana M., Oliveira, Douglas M., Dias, Suelen S. G., Bastos, Viviane A., Santos, Marlon D. M., Carvalho, Paulo C., Valente, Richard H., Hottz, Eugenio D., Bozza, Fernando A., Souza, Thiago Moreno L., Perales, Jonas, Bozza, Patrícia T.

“…Coronavirus disease 2019 (COVID-19) has affected over 400 million people worldwide, leading to 6 million deaths. Among the complex symptomatology of COVID-19,…”
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Preclinical development of kinetin as a safe error-prone SARS-CoV-2 antiviral able to attenuate virus-induced inflammation by Souza, Thiago Moreno L., Pinho, Vagner D., Setim, Cristina F., Sacramento, Carolina Q., Marcon, Rodrigo, Fintelman-Rodrigues, Natalia, Chaves, Otavio A., Heller, Melina, Temerozo, Jairo R., Ferreira, André C., Mattos, Mayara, Momo, Patrícia B., Dias, Suelen S. G., Gesto, João S. M., Pereira-Dutra, Filipe, Viola, João P. B., Queiroz-Junior, Celso Martins, Guimarães, Lays Cordeiro, Chaves, Ian Meira, Guimarães, Pedro Pires Goulart, Costa, Vivian Vasconcelos, Teixeira, Mauro Martins, Bou-Habib, Dumith Chequer, Bozza, Patrícia T., Aguillón, Anderson R., Siqueira-Junior, Jarbas, Macedo-Junior, Sergio, Andrade, Edineia L., Fadanni, Guilherme P., Tolouei, Sara E. L., Potrich, Francine B., Santos, Adara A., Marques, Naiani F., Calixto, João B., Rabi, Jaime A.

“…Orally available antivirals against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are necessary because of the continuous circulation of new…”
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The Chemokine CCL5 Inhibits the Replication of Influenza A Virus Through SAMHD1 Modulation by Silva, Thauane, Temerozo, Jairo R, do Vale, Gabriele, Ferreira, André C, Soares, Vinícius Cardoso, Dias, Suelen Silva Gomes, Sardella, Gabriela, Bou-Habib, Dumith Chequer, Siqueira, Marilda, Souza, Thiago Moreno L, Miranda, Milene

“…Influenza A virus (IAV) is the main etiological agent of acute respiratory tract infections. During IAV infection, interferon triggers the overexpression of…”
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Computational and Experimental Approaches Identify Beta-Blockers as Potential SARS-CoV‑2 Spike Inhibitors by Puhl, Ana C., Mottin, Melina, Sacramento, Carolina Q., Tavella, Tatyana Almeida, Dias, Gabriel Gonçalves, Fintelman-Rodrigues, Natalia, Temerozo, Jairo R., Dias, Suelen S. G., Ramos, Paulo Ricardo Pimenta da Silva, Merten, Eric M., Pearce, Kenneth H., Costa, Fabio Trindade Maranhão, Premkumar, Lakshmanane, Souza, Thiago Moreno L., Andrade, Carolina Horta, Ekins, Sean

“…Finding antivirals for SARS-CoV-2 is still a major challenge, and many computational and experimental approaches have been employed to find a solution to this…”
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Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators by Dias, Suelen Silva Gomes, Soares, Vinicius Cardoso, Ferreira, André C, Sacramento, Carolina Q, Fintelman-Rodrigues, Natalia, Temerozo, Jairo R, Teixeira, Lívia, Nunes da Silva, Marcos Alexandre, Barreto, Ester, Mattos, Mayara, de Freitas, Caroline S, Azevedo-Quintanilha, Isaclaudia G, Manso, Pedro Paulo A, Miranda, Milene D, Siqueira, Marilda Mendonça, Hottz, Eugenio D, Pão, Camila R R, Bou-Habib, Dumith C, Barreto-Vieira, Debora F, Bozza, Fernando A, Souza, Thiago M L, Bozza, Patricia T

“…Viruses are obligate intracellular parasites that make use of the host metabolic machineries to meet their biosynthetic needs. Thus, identifying the host…”
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Correction: SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes by Ferreira, André C., Soares, Vinicius Cardoso, de Azevedo-Quintanilha, Isaclaudia G., Dias, Suelen da Silva Gomes, Fintelman-Rodrigues, Natalia, Sacramento, Carolina Q., Mattos, Mayara, de Freitas, Caroline S., Temerozo, Jairo R., Teixeira, Lívia, Hottz, Eugenio Damaceno, Barreto, Ester A., Pão, Camila R. R., Palhinha, Lohanna, Miranda, Milene, Bou-Habib, Dumith Chequer, Bozza, Fernando A., Bozza, Patrícia T., Souza, Thiago Moreno L.

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Metabolic reprogramming and lipid droplets are involved in Zika virus replication in neural cells by Dias, Suelen Silva Gomes, Cunha-Fernandes, Tamires, Souza-Moreira, Luciana, Soares, Vinicius Cardoso, Lima, Giselle Barbosa, Azevedo-Quintanilha, Isaclaudia G, Santos, Julia, Pereira-Dutra, Filipe, Freitas, Caroline, Reis, Patricia A, Rehen, Stevens Kastrup, Bozza, Fernando A, Souza, Thiago M Lopes, de Almeida, Cecilia J G, Bozza, Patricia T

“…Zika virus (ZIKV) infection is a global public health concern linked to adult neurological disorders and congenital diseases in newborns. Host lipid…”
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Simvastatin Downregulates the SARS-CoV-2-Induced Inflammatory Response and Impairs Viral Infection Through Disruption of Lipid Rafts by Teixeira, Lívia, Temerozo, Jairo R, Pereira-Dutra, Filipe S, Ferreira, André Costa, Mattos, Mayara, Gonçalves, Barbara Simonson, Sacramento, Carolina Q, Palhinha, Lohanna, Cunha-Fernandes, Tamires, Dias, Suelen S G, Soares, Vinicius Cardoso, Barreto, Ester A, Cesar-Silva, Daniella, Fintelman-Rodrigues, Natalia, Pão, Camila R R, de Freitas, Caroline S, Reis, Patrícia A, Hottz, Eugenio D, Bozza, Fernando A, Bou-Habib, Dumith C, Saraiva, Elvira M, de Almeida, Cecília J G, Viola, João P B, Souza, Thiago Moreno L, Bozza, Patricia T

“…Coronavirus disease 2019 (COVID-19) is currently a worldwide emergency caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In observational…”
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Increased platelet activation and platelet-inflammasome engagement during chikungunya infection by Gomes de Azevedo-Quintanilha, Isaclaudia, Campos, Mariana Macedo, Teixeira Monteiro, Ana Paula, Dantas do Nascimento, Alessandra, Calheiros, Andrea Surrage, Oliveira, Douglas Mathias, Dias, Suelen Silva Gomes, Soares, Vinicius Cardoso, Santos, Julia da Cunha, Tavares, Isabel, Lopes Souza, Thiago Moreno, Hottz, Eugenio D., Bozza, Fernando A., Bozza, Patricia T.

“…Chikungunya fever is a viral disease transmitted by mosquitoes of the genus Aedes. The infection is usually symptomatic and most common symptoms are fever…”
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Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant Cells by Sacramento, Carolina Q, Fintelman-Rodrigues, Natalia, Dias, Suelen S G, Temerozo, Jairo R, Da Silva, Aline de Paula D, da Silva, Carine S, Blanco, Camilla, Ferreira, André C, Mattos, Mayara, Soares, Vinicius C, Pereira-Dutra, Filipe, Miranda, Milene Dias, Barreto-Vieira, Debora F, da Silva, Marcos Alexandre N, Santos, Suzana S, Torres, Mateo, Chaves, Otávio Augusto, Rajoli, Rajith K R, Paccanaro, Alberto, Owen, Andrew, Bou-Habib, Dumith Chequer, Bozza, Patrícia T, Souza, Thiago Moreno L

“…Despite the development of specific therapies against severe acute respiratory coronavirus 2 (SARS-CoV-2), the continuous investigation of the mechanism of…”
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