Search Results - "Dias, Simoni C"
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Antimicrobial Peptides and Nanotechnology, Recent Advances and Challenges
Published in Frontiers in microbiology (08-05-2018)“…Antimicrobial peptides are sequences of amino acids, which present activity against microorganisms. These peptides were discovered over 70 years ago, and are…”
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Evaluation of an antimicrobial L-amino acid oxidase and peptide derivatives from Bothropoides mattogrosensis pitviper venom
Published in PloS one (16-03-2012)“…Healthcare-associated infections (HAIs) are causes of mortality and morbidity worldwide. The prevalence of bacterial resistance to common antibiotics has…”
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Comparative NanoUPLC-MSE analysis between magainin I-susceptible and -resistant Escherichia coli strains
Published in Scientific reports (23-06-2017)“…In recent years the antimicrobial peptides (AMPs) have been prospected and designed as new alternatives to conventional antibiotics. Indeed, AMPs have…”
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Molecular farming of antimicrobial peptides: available platforms and strategies for improving protein biosynthesis using modified virus vectors
Published in Anais da Academia Brasileira de Ciências (01-01-2019)“…The constant demand for new antibiotic drugs has driven efforts by the scientific community to prospect for peptides with a broad spectrum of action. In this…”
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Functional characterization of a synthetic hydrophilic antifungal peptide derived from the marine snail Cenchritis muricatus
Published in Biochimie (01-04-2012)“…Antimicrobial peptides have been found in mollusks and other sea animals. In this report, a crude extract of the marine snail Cenchritis muricatus was…”
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Exploring the pharmacological potential of promiscuous host-defense peptides: from natural screenings to biotechnological applications
Published in Frontiers in microbiology (01-01-2011)“…In the last few years, the number of bacteria with enhanced resistance to conventional antibiotics has dramatically increased. Most of such bacteria belong to…”
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Investigating specific bacterial resistance to AMPs by using a magainin I-resistant Escherichia coli model
Published in Journal of antibiotics (01-10-2014)“…Antimicrobial peptides (AMPs) are multifunctional compounds that may show antimicrobial and immunomodulatory activities. With the rapid increase in the…”
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Genomic Comparison among Lethal Invasive Strains of Streptococcus pyogenes Serotype M1
Published in Frontiers in microbiology (23-10-2017)“…, also known as group A (GAS), is a human pathogen that causes diverse human diseases including streptococcal toxic shock syndrome (STSS). A GAS outbreak…”
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The next generation of antimicrobial peptides (AMPs) as molecular therapeutic tools for the treatment of diseases with social and economic impacts
Published in Drug discovery today (01-02-2017)“…•Review of the present status of the development of antimicrobial peptides (AMPs).•Recent advances in designing new anti-infective agents with enhanced…”
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Clavanin A-bioconjugated Fe 3 O 4 /Silane core-shell nanoparticles for thermal ablation of bacterial biofilms
Published in Colloids and surfaces, B, Biointerfaces (01-09-2018)“…The use of central venous catheters (CVC) is highly associated with nosocomial blood infections and its use largely requires a systematic assessment of…”
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Current scenario of peptide-based drugs: the key roles of cationic antitumor and antiviral peptides
Published in Frontiers in microbiology (2013)“…Cationic antimicrobial peptides (AMPs) and host defense peptides (HDPs) show vast potential as peptide-based drugs. Great effort has been made in order to…”
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Toxicological and Histological Evaluation of Bothrops itapetiningae Venom
Published in Journal of herpetology (01-12-2012)“…Envenomation by snakes of the genus Bothrops is characterized by local pain, systemic bleeding, tachycardia, acute renal failure, as well as swelling and…”
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Clavanin A-bioconjugated Fe3O4/Silane core-shell nanoparticles for thermal ablation of bacterial biofilms
Published in Colloids and surfaces, B, Biointerfaces (01-09-2018)“…[Display omitted] •We developed a simple strategy that employs a bifunctional clavanin A/Fe3O4 hybrid nanosystem.•CVC tubing was modified by immobilization of…”
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Identification and Structural Characterization of Novel Cyclotide with Activity against an Insect Pest of Sugar Cane
Published in The Journal of biological chemistry (02-01-2012)“…Cyclotides are a family of plant-derived cyclic peptides comprising six conserved cysteine residues connected by three intermolecular disulfide bonds that form…”
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Comparative transcriptome analyses of magainin I-susceptible and -resistant Escherichia coli strains
Published in Microbiology (Society for General Microbiology) (01-11-2018)“…Antimicrobial peptides (AMPs) have attracted considerable attention because of their multiple and complex mechanisms of action toward resistant bacteria…”
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Cm‐p5: an antifungal hydrophilic peptide derived from the coastal mollusk Cenchritis muricatus (Gastropoda: Littorinidae)
Published in The FASEB journal (01-08-2015)“…Antimicrobial peptides form part of the first line of defense against pathogens formany organisms. Current treatments for fungal infections are limited by drug…”
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An Immunomodulatory Peptide Confers Protection in an Experimental Candidemia Murine Model
Published in Antimicrobial agents and chemotherapy (01-08-2017)“…Fungal species are commensals present in the mammalian skin and mucous membranes. spp. are capable of breaching the epithelial barrier of immunocompromised…”
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Characterization of a Bioactive Acyclotide from Palicourea rigida
Published in Journal of natural products (Washington, D.C.) (23-11-2016)“…The extraction and purification of parigidin-br3, a cyclotide analogue belonging to the “bracelet” subfamily, from Palicourea rigida leaves is discussed…”
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The intrinsic antimicrobial activity of citric acid-coated manganese ferrite nanoparticles is enhanced after conjugation with the antifungal peptide Cm-p5
Published in International journal of nanomedicine (01-01-2016)“…Diseases caused by bacterial and fungal pathogens are among the major health problems in the world. Newer antimicrobial therapies based on novel molecules…”
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Controlling resistant bacteria with a novel class of β-lactamase inhibitor peptides: from rational design to in vivo analyses
Published in Scientific reports (11-08-2014)“…Peptide rational design was used here to guide the creation of two novel short β-lactamase inhibitors, here named dBLIP-1 and -2, with length of five amino…”
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