Search Results - "Dias, Joana N. R."

Establishment of a bioluminescent canine B-cell lymphoma xenograft model for monitoring tumor progression and treatment response in preclinical studies by Dias, Joana N R, André, Ana S, Aguiar, Sandra I, Ministro, Joana, Oliveira, Joana, Peleteiro, Maria C, Rütgen, Barbara, Gano, Lurdes, Correia, João D G, Oliveira, Soraia S, Goncalves, Joao, Gil, Solange, Tavares, Luís, Aires-da-Silva, Frederico

“…Canine diffuse large B-cell lymphoma (DLBCL) is one of the most common cancers in dogs which shares remarkable similarities with its human counterpart, making…”
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Liposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance by Ferreira, Magda, Ogren, Maria, Dias, Joana N R, Silva, Marta, Gil, Solange, Tavares, Luís, Aires-da-Silva, Frederico, Gaspar, Maria Manuela, Aguiar, Sandra Isabel

“…Antimicrobial drugs are key tools to prevent and treat bacterial infections. Despite the early success of antibiotics, the current treatment of bacterial…”
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In vivo Phage Display: A promising selection strategy for the improvement of antibody targeting and drug delivery properties by André, Ana S, Moutinho, Isa, Dias, Joana N R, Aires-da-Silva, Frederico

“…The discovery of hybridoma technology, described by Kohler and Milstein in 1975, and the resulting ability to generate monoclonal antibodies (mAbs) initiated a…”
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Characterization of the canine CD20 as a therapeutic target for comparative passive immunotherapy by Dias, Joana N. R., Almeida, André, André, Ana S., Aguiar, Sandra I., Bule, Pedro, Nogueira, Sara, Oliveira, Soraia S., Carrapiço, Belmira, Gil, Solange, Tavares, Luís, Aires-da-Silva, Frederico

“…Anti-CD20 therapies have revolutionized the treatment of B-cell malignancies. Despite these advances, relapsed and refractory disease remains a major treatment…”
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Rabbit derived VL single-domains as promising scaffolds to generate antibody–drug conjugates by André, Ana S., Dias, Joana N. R., Aguiar, Sandra, Nogueira, Sara, Bule, Pedro, Carvalho, Joana Inês, António, João P. M., Cavaco, Marco, Neves, Vera, Oliveira, Soraia, Vicente, Gonçalo, Carrapiço, Belmira, Braz, Berta São, Rütgen, Barbara, Gano, Lurdes, Correia, João D. G., Castanho, Miguel, Goncalves, Joao, Gois, Pedro M. P., Gil, Solange, Tavares, Luís, Aires-da-Silva, Frederico

“…Antibody–drug conjugates (ADCs) are among the fastest-growing classes of therapeutics in oncology. Although ADCs are in the spotlight, they still present…”
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Highly specific blood-brain barrier transmigrating single-domain antibodies selected by an In Vivo phage display screening by Aguiar, Sandra Isabel, Dias, Joana, Santos André, Ana Filipa, Silva, Lisete M., Martins, Diana, Carrapiço, Belmira, Castanho, Miguel, Carriço, João, Cavaco, Marco, Aires da Silva, Frederico, [et al.]

“…Research Areas: Pharmacology & Pharmacy A major bottleneck in the successful development of central nervous system (CNS) drugs is the discovery and design of…”
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Immunotherapeutic Strategies for Canine Lymphoma: Changing the Odds Against Non-Hodgkin Lymphoma by Dias, Joana N. R., André, Ana S., Aguiar, Sandra I., Gil, Solange, Tavares, Luís, Aires-da-Silva, Frederico

“…Graphical Abstract The application of canine lymphoma as an animal model for immunotherapeutic approaches in comparative medicine provides an integrated drug…”
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Panobinostat-loaded folate targeted liposomes as a promising drug delivery system for treatment of canine B-cell lymphoma by André, Ana S., Dias, Joana N. R., Aguiar, Sandra I., Leonardo, Ana, Nogueira, Sara, Amaral, Joana D., Fernandes, Célia, Gano, Lurdes, Correia, João D. G., Cavaco, Marco, Neves, Vera, Correia, Jorge, Castanho, Miguel, Rodrigues, Cecília M. P., Gaspar, Maria Manuela, Tavares, Luís, Aires-da-Silva, Frederico

“…Introduction Cancer is a major public health problem with over 19 million cases reported in 2020. Similarly to humans, dogs are also largely affected by…”
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Diazaborines Are a Versatile Platform to Develop ROS‐Responsive Antibody Drug Conjugates by António, João P. M., Carvalho, Joana Inês, André, Ana S., Dias, Joana N. R., Aguiar, Sandra I., Faustino, Hélio, Lopes, Ricardo M. R. M., Veiros, Luis F., Bernardes, Gonçalo J. L., Silva, Frederico A., Gois, Pedro M. P.

“…Antibody–drug conjugates (ADCs) are a new class of therapeutics that combine the lethality of potent cytotoxic drugs with the targeting ability of antibodies…”
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Canine multicentric lymphoma exhibits systemic and intratumoral cytokine dysregulation by Dias, Joana N.R., Lopes, Mariana, Peleteiro, Conceição, Vicente, Gonçalo, Nunes, Telmo, Mateus, Luísa, Aires-da-Silva, Frederico, Tavares, Luís, Gil, Solange

“…Non-Hodgkin Lymphoma (NHL) is among the most common neoplasias in dogs and humans. Owing to remarkable similarities with its human counterpart, the canine…”
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Diazaborines Are a Versatile Platform to Develop ROS‐Responsive Antibody Drug Conjugates by António, João P. M., Carvalho, Joana Inês, André, Ana S., Dias, Joana N. R., Aguiar, Sandra I., Faustino, Hélio, Lopes, Ricardo M. R. M., Veiros, Luis F., Bernardes, Gonçalo J. L., Silva, Frederico A., Gois, Pedro M. P.

“…Antibody–drug conjugates (ADCs) are a new class of therapeutics that combine the lethality of potent cytotoxic drugs with the targeting ability of antibodies…”
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The histone deacetylase inhibitor panobinostat is a potent antitumor agent in canine diffuse large B-cell lymphoma by Dias, Joana N R, Aguiar, Sandra I, Pereira, Diane M, André, Ana S, Gano, Lurdes, Correia, João D G, Carrapiço, Belmira, Rütgen, Barbara, Malhó, Rui, Peleteiro, Conceição, Goncalves, João, Rodrigues, Cecília M P, Gil, Solange, Tavares, Luís, Aires-da-Silva, Frederico

“…Non-Hodgkin lymphoma (NHL) is one of the most common causes of cancer-related death in the United States and Europe. Although the outcome of NHL patients has…”
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