Search Results - "Dias, G. M"
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Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism
Published in Proceedings of the National Academy of Sciences - PNAS (24-01-2012)“…Glutamine is an essential nutrient for cancer cell proliferation, especially in the context of citric acid cycle anaplerosis. In this manuscript we present…”
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Multifactorial Basis and Therapeutic Strategies in Metabolism-Related Diseases
Published in Nutrients (01-08-2021)“…Throughout the 20th and 21st centuries, the incidence of non-communicable diseases (NCDs), also known as chronic diseases, has been increasing worldwide…”
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Architecture and regulation of filamentous human cystathionine beta-synthase
Published in Nature communications (04-04-2024)“…Cystathionine beta-synthase (CBS) is an essential metabolic enzyme across all domains of life for the production of glutathione, cysteine, and hydrogen…”
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Cry1Ac toxin binding in the velvetbean caterpillar Anticarsia gemmatalis: study of midgut aminopeptidases N
Published in Frontiers in physiology (29-10-2024)“…The velvetbean caterpillar Anticarsia gemmatalis is one of the main soybean defoliators in Brazil. Currently, the main biopesticide used to control insect…”
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Using microRNA Networks to Understand Cancer
Published in International journal of molecular sciences (26-06-2018)“…Human cancers are characterized by deregulated expression of multiple microRNAs (miRNAs), involved in essential pathways that confer the malignant cells their…”
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Paclobutrazol reduces growth and increases chlorophyll indices and gas exchanges of basil (Ocimum basilicum)
Published in Brazilian journal of biology (2022)“…Abstract Basil (Ocimum basilicum) is a medicinal, ornamental and aromatic plant, however, its size can be an obstacle to its commercialization as a potted…”
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Machine Grading of High-Density Hardwoods (Southern Blue Gum) from Tensile Testing
Published in Forests (01-08-2023)“…Hardwoods commonly have high mechanical properties, which makes them interesting for structural use, but softwoods dominate the structural timber market in…”
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Spatial and temporal diversity of non-native biofouling species associated with marinas in two Angolan bays
Published in African journal of marine science (01-10-2020)“…Artificial structures in coastal areas provide substrates which facilitate the spread of non-native species. Published records of introduced benthic species in…”
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Insights on Potential Photoprotective Activity of Two Butylchalcone Derivatives: Synthesis, Spectroscopic Characterization and Molecular Modeling
Published in Photonics (01-03-2023)“…The development of photoprotective agents presents a growing interest due to skin disorders, e.g., cancer. In order to obtain natural-based compounds with…”
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Influence of the Geometric Properties, the Timber–Concrete Interface, and the Load Protocol on the Mechanical Properties of Timber–Concrete Composite Connections
Published in Applied sciences (01-08-2024)“…Timber–concrete composite (TCC) structural systems are characterized by the combination of timber and concrete, which are connected to transmit shear forces…”
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Analysis of the Influence of Microwave Treatment Parameters of Wood
Published in Forests (01-02-2023)“…Microwave (MW) treatment is an effective method in the wood modification field. It has become more popular in the past decade since it enhances wood…”
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Influence of the Wood Species, Forest Management Practice and Allocation Method on the Environmental Impacts of Roundwood and Biomass
Published in Forests (01-09-2022)“…This study quantifies and compares the environmental impacts of production systems of biomass and roundwood from different wood species—maritime pine,…”
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Study of the Influence of Heat Treatment on OSB Panels Produced with Eucalyptus Wood in Different Layer Compositions
Published in Forests (01-12-2022)“…In view of the lack of studies aimed at producing and assessing the effects of heat treatment of Oriented Strand Board (OSB) panels, this paper evaluated the…”
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A biotechnological perspective on the application of iron oxide magnetic colloids modified with polysaccharides
Published in Biotechnology advances (2011)“…Iron oxide magnetic nanoparticles (MNPs) alone are suitable for a broad spectrum of applications, but the low stability and heterogeneous size distribution in…”
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Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors
Published in Journal of medicinal chemistry (14-05-2020)“…Tuberculosis (TB) remains a leading cause of mortality among infectious diseases worldwide. InhA has been the focus of numerous drug discovery efforts as this…”
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Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation
Published in Cancer cell (14-09-2010)“…Rho GTPases impact a number of activities important for oncogenesis. We describe a small molecule inhibitor that blocks oncogenic transformation induced by…”
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The molecular basis for the regulation of the cap-binding complex by the importins
Published in Nature structural & molecular biology (01-09-2009)“…The cap binding complex (CBC) interacts with mRNAs and snRNAs and accompanies them to the cytoplasm, where they are released and CBC is imported back into the…”
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pH and the Breast Cancer Recurrent Mutation D538G Affect the Process of Activation of Estrogen Receptor α
Published in Biochemistry (Easton) (15-03-2022)“…Estrogen receptor α (ERα) is a regulatory protein that can access a set of distinct structural configurations. ERα undergoes extensive remodeling as it…”
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Functional Diversification of Cerato-Platanins in Moniliophthora perniciosa as Seen by Differential Expression and Protein Function Specialization
Published in Molecular plant-microbe interactions (01-11-2013)“…Cerato-platanins (CP) are small, cysteine-rich fungal-secreted proteins involved in the various stages of the host-fungus interaction process, acting as…”
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Correction to Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors
Published in Journal of medicinal chemistry (13-08-2020)Get full text
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