Search Results - "Dias, Daniel A."
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1
pharmaceutical industry and natural products: historical status and new trends
Published in Phytochemistry reviews (01-04-2015)“…Owing to the high diversity of terrestrial and marine organisms, natural products (secondary metabolites) are some of the most successful source of drug leads…”
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Understanding glycaemic control and current approaches for screening antidiabetic natural products from evidence-based medicinal plants
Published in Plant methods (07-09-2019)“…Type 2 Diabetes Mellitus has reached epidemic proportions as a result of over-nutrition and increasingly sedentary lifestyles. Current therapies, although…”
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3
A historical overview of natural products in drug discovery
Published in Metabolites (16-04-2012)“…Historically, natural products have been used since ancient times and in folklore for the treatment of many diseases and illnesses. Classical natural product…”
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4
Therapeutic Potential of α- and β-Pinene: A Miracle Gift of Nature
Published in Biomolecules (Basel, Switzerland) (14-11-2019)“…α- and β-pinene are well-known representatives of the monoterpenes group, and are found in many plants' essential oils. A wide range of pharmacological…”
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Innovative Alternative Technologies to Extract Carotenoids from Microalgae and Seaweeds
Published in Marine Drugs (22-11-2016)“…Marine microalgae and seaweeds (microalgae) represent a sustainable source of various bioactive natural carotenoids, including β-carotene, lutein, astaxanthin,…”
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6
Normalizing and Integrating Metabolomics Data
Published in Analytical chemistry (Washington) (18-12-2012)“…Metabolomics research often requires the use of multiple analytical platforms, batches of samples, and laboratories, any of which can introduce a component of…”
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Inhibitory effect of a weight-loss Chinese herbal formula RCM-107 on pancreatic α-amylase activity: Enzymatic and in silico approaches
Published in PloS one (29-04-2020)“…Reducing carbohydrates digestion by having a low glycaemic index (GI) foods has been linked to weight loss. Inhibiting related enzymes is an alternative way to…”
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Lipid profile remodeling in response to nitrogen deprivation in the microalgae Chlorella sp. (Trebouxiophyceae) and Nannochloropsis sp. (Eustigmatophyceae)
Published in PloS one (29-08-2014)“…Many species of microalgae produce greatly enhanced amounts of triacylglycerides (TAGs), the key product for biodiesel production, in response to specific…”
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Microbiota and Metabolite Profiling Combined With Integrative Analysis for Differentiating Cheeses of Varying Ripening Ages
Published in Frontiers in microbiology (26-11-2020)“…Cheese maturation and flavor development results from complex interactions between milk substrates, cheese microbiota and their metabolites. In this study,…”
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Current and Future Perspectives on the Structural Identification of Small Molecules in Biological Systems
Published in Metabolites (15-12-2016)“…Although significant advances have been made in recent years, the structural elucidation of small molecules continues to remain a challenging issue for…”
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11
Author Correction: New insights into cheddar cheese microbiota-metabolome relationships revealed by integrative analysis of multi-omics data
Published in Scientific reports (25-01-2021)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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12
The stock of external sovereign debt: Can we take the data at ‘face value’?
Published in Journal of international economics (01-09-2014)“…The stock of sovereign debt is typically measured at face value. Defined as the undiscounted sum of future principal repayments, face values are misleading…”
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Price Setting in the Euro Area: Some Stylized Facts from Individual Producer Price Data
Published in Journal of money, credit and banking (01-12-2012)“…This paper summarizes the microevidence on the setting of producer prices in the euro area. The main findings are: (i) 21% of producer prices are adjusted each…”
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14
Mapping carbon fate during bleaching in a model cnidarian symbiosis: the application of 13C metabolomics
Published in The New phytologist (01-06-2017)“…Summary Coral bleaching is a major threat to the persistence of coral reefs. Yet we lack detailed knowledge of the metabolic interactions that determine…”
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15
Metabolomics of capsicum ripening reveals modification of the ethylene related-pathway and carbon metabolism
Published in Postharvest biology and technology (01-03-2014)“…•Metabolic profiling was undertaken using GC–MS of three capsicum ripening stages.•LC–MS and enzymatic analyses were used to further analyse more ripening…”
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A Novel Glutathione-Hydroxycinnamic Acid Product Generated in Oxidative Wine Conditions
Published in Journal of agricultural and food chemistry (12-12-2012)“…This study characterizes a novel glutathione-substituted dihydroxyphenyl compound formed during the oxidation of white wine and model wine solutions, which may…”
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In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites
Published in International journal for parasitology -- drugs and drug resistance (01-12-2021)“…The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were…”
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L-Sulforaphane Confers Protection Against Oxidative Stress in an In Vitro Model of Age-Related Macular Degeneration
Published in Current molecular pharmacology (01-01-2018)“…In age-related macular degeneration, oxidative damage and abnormal neovascularization in the retina are caused by the upregulation of vascular endothelium…”
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Measures of insulin sensitivity, leptin, and adiponectin concentrations in cats in diabetic remission compared to healthy control cats
Published in Frontiers in veterinary science (29-07-2022)“…Objectives Firstly, to compare differences in insulin, adiponectin, leptin, and measures of insulin sensitivity between diabetic cats in remission and healthy…”
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Lipidomics reveal the protective effects of a vegetable-derived isothiocyanate against retinal degeneration [version 5; peer review: 3 approved, 1 not approved]
Published in F1000 research (2019)“…Background: Age-related macular degeneration (AMD) is a leading cause of blindness in the ageing population. Without effective treatment strategies that can…”
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