A small scale study to evaluate the efficacy of microneedling in the presence or absence of platelet‐rich plasma in the treatment of post‐clipping alopecia in dogs
Background Post‐clipping alopecia often has a clinically poor response to therapy and prolonged alopecia is a source of anxiety for some owners. In humans and dogs, superficial microtrauma via a microneedling (MN) device induces mechanical stimulation of the hair follicle with resultant hair regrowt...
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| Published in: | Veterinary dermatology Vol. 31; no. 3; pp. 214 - e45 |
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| Main Authors: | , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
England
Wiley Subscription Services, Inc
01-06-2020
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| Subjects: | |
| Online Access: | Get full text |
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| Summary: | Background
Post‐clipping alopecia often has a clinically poor response to therapy and prolonged alopecia is a source of anxiety for some owners. In humans and dogs, superficial microtrauma via a microneedling (MN) device induces mechanical stimulation of the hair follicle with resultant hair regrowth. Human studies suggest that concurrent application of platelet‐rich plasma (PRP) with MN induces more rapid regrowth of better‐quality hair than microneedling alone.
Hypothesis
Microneedling with PRP will induce more rapid regrowth of better quality hair.
Animals
Four unrelated client‐owned dogs diagnosed with post‐clipping alopecia.
Methods and Materials
This was a prospective study. The affected site was divided in half, with the first half treated with MN alone and the second half treated with MN + PRP. Hair regrowth was assessed by clinician and owner using a hair growth assessment scale (HGAS) at one, three, six and 12 months.
Results
At three months, all dogs had improved and three exhibited greater hair regrowth on the MN + PRP side. A similar response was noted bilaterally in three dogs, which had improved by 76–100% at six months and remained unchanged at 12 months. One dog improved by < 26% at six months, but had> 50% re‐growth by 12 months. The small sample size precluded statistical analysis.
Conclusions and clinical importance
In dogs with post‐clipping alopecia, MN + PRP appeared to induce more rapid hair regrowth than MN; however, overall results were visibly equivalent by six months regardless of method. Both MN and MN + PRP proved successful for treating post‐clipping alopecia.
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Background – Post‐clipping alopecia often has a clinically poor response to therapy, and prolonged alopecia is a source of anxiety for some owners. In humans and dogs, superficial microtrauma via a microneedling (MN) device induces mechanical stimulation of the hair follicle with resultant hair regrowth. Human studies suggest that concurrent application of platelet‐rich plasma (PRP) with MN induces more rapid regrowth of better quality hair than microneedling alone. Hypothesis – Microneedling with PRP will induce more rapid regrowth of better‐quality hair than MN alone. Conclusions and clinical importance – In dogs with post‐clipping alopecia, MN + PRP appeared to induce more rapid hair regrowth than MN; however, overall results were visibly equivalent by six months regardless of method. Both MN and MN + PRP proved successful for treating post‐clipping alopecia. |
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| Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ISSN: | 0959-4493 1365-3164 |
| DOI: | 10.1111/vde.12821 |