Search Results - "Diallo, Béré"
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SAR442085, a novel anti-CD38 antibody with enhanced antitumor activity against multiple myeloma
Published in Blood (24-02-2022)“…Anti-CD38 monoclonal antibodies (mAbs) represent a breakthrough in the treatment of multiple myeloma (MM), yet some patients fail to respond or progress…”
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BMFPs, a versatile therapeutic tool for redirecting a preexisting Epstein-Barr virus antibody response toward defined target cells
Published in Science advances (11-02-2022)“…Industrial production of therapeutic monoclonal antibodies is mostly performed in eukaryotic-based systems, allowing posttranslational modifications mandatory…”
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A rationally-engineered IL-2 improves the antitumor effect of anti-CD20 therapy
Published in Oncoimmunology (01-01-2020)“…Anti-CD20 treatment represents a therapeutic benefit for patients with B-cell lymphomas, although more efficient therapies are needed for refractory or…”
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Intranasal COVID-19 vaccine induces respiratory memory T cells and protects K18-hACE mice against SARS-CoV-2 infection
Published in npj vaccines (13-05-2023)“…Current COVID-19 vaccines prevent severe disease, but do not induce mucosal immunity or prevent infection with SARS-CoV-2, especially with recent variants…”
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MAbs: the history of a basic research or the curiosity as a source of wealth
Published in M.S. Médecine sciences (06-01-2020)“…In 2019, monoclonal antibodies are a worldwide annual business worth of more than 100 billions USD (i.e., about 90 billions €). In addition to their use in the…”
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Abstract 2266: SAR442085, a next generation anti-CD38 antibody with enhanced antibody-dependent cellular cytotoxicity (ADCC) against multiple myeloma
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract CD38 is a cell surface glycoprotein highly expressed in multiple myeloma (MM) cells making it an attractive target for antibody–based therapy…”
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Selumetinib-based therapy in uveal melanoma patient-derived xenografts
Published in Oncotarget (24-04-2018)“…The prognosis of metastatic uveal melanoma (UM) is among the worst of all human cancers. The identification of near-ubiquitous GNAQ/GNA11 mutations and the…”
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Abstract 5782: Selumetinib-based therapy in uveal melanoma patient-derived xenografts
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Purpose: The prognosis of metastatic uveal melanoma (UM) patients remains one of the worst observed in human cancers. The identification of frequently…”
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Abstract 2087: The MEK1/2 inhibitor selumetinib (AZD6244; ARRY-142886) appears as an efficient targeted therapy when used in an adjuvant setting in patient-derived xenografts of uveal melanoma
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Uveal melanomas (UM) constitute the most common primary intraocular tumors in adults and are characterized by a constitutive activation of the MAPK…”
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