Search Results - "Diaguarachchige De Silva, Kalsha"
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Characterization of a novel FADS2 transcript variant: implications for D6D activity regulation in cells
Published in Biochemistry and cell biology (01-11-2021)“…Delta-6-desaturase (D6D) activity is deficient in MCF-7 and other cancer cell lines, but it is not explained by gene mutations. This deficient activity was not…”
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Renal tubule-specific Atgl deletion links kidney lipid metabolism to glucagon-like peptide 1 and insulin secretion independent of renal inflammation or lipotoxicity
Published in Molecular metabolism (Germany) (01-03-2024)“…Lipotoxic injury from renal lipid accumulation in obesity and type 2 diabetes (T2D) is implicated in associated kidney damage. However, models examining…”
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Transcription factor CREB3 is a potent regulator of high-fat diet-induced obesity and energy metabolism
Published in International Journal of Obesity (01-08-2022)“…Background The endoplasmic reticulum senses alterations to cellular homeostasis that activates the unfolded protein response (UPR). UPR proteins are known to…”
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Relative expression and regulation by short‐term fasting of lysophosphatidic acid receptors and autotaxin in white and brown adipose tissue depots
Published in Lipids (01-05-2020)“…Lysophosphatidic acid (lysoPtdOH) levels have previously been reported to decrease in rodents with short‐term fasting. We investigated whether a 16 h fast…”
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Female Renal Tubule-Specific Adipose Triglyceride Lipase Knockout Mice Develop Glucose Intolerance With Advancing Age
Published in Canadian journal of diabetes (01-11-2021)Get full text
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