What Is the Comparative Efficacy of Surgical, Endoscopic, Transanal Resection, and Radiotherapy Modalities in the Treatment of Rectal Cancer?

What Is the Comparative Efficacy of Surgical, Endoscopic, Transanal Resection, and Radiotherapy Modalities in the Treatment of Rectal Cancer?

Rectal cancer is a significant healthcare burden, and effective treatment is crucial. This research aims to compare the effectiveness of surgical and endoscopic resection, transanal resection, and radiotherapy. A literature analysis was conducted in order to identify relevant studies, by comparing t...

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Bibliographic Details
Published in:Healthcare (Basel) Vol. 11; no. 16; p. 2347
Main Authors: Isaic, Alexandru, Motofelea, Alexandru Cătălin, Costachescu, Dan, Pop, Gheorghe Nicusor, Totolici, Bogdan, Popovici, Dorel, Diaconescu, Razvan Gheorghe
Format: Journal Article
Language:English
Published: Switzerland MDPI AG 01-08-2023
MDPI
Subjects:
Biopsy
Cancer therapies
Care and treatment
Cell division
Colonoscopy
Colorectal cancer
Empowerment
Endoscopy
Lymphatic system
Medical prognosis
Microsurgery
Mortality
Mutation
Patients
Radiation therapy
Radiotherapy
Rectum
Review
Surgery, Experimental
Surgical research
Surgical techniques
TaTME
TEM
TME
Tumors
White people
Romania
United States > US
radiotherapy
TaTME
TEM
TME
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Summary:Rectal cancer is a significant healthcare burden, and effective treatment is crucial. This research aims to compare the effectiveness of surgical and endoscopic resection, transanal resection, and radiotherapy. A literature analysis was conducted in order to identify relevant studies, by comparing the different surgical approaches and variables affecting treatment decisions. The findings were analyzed and synthesized to provide a comprehensive overview. Surgical treatment, particularly TME (total mesorectal excision), proved consistent efficacy in achieving complete tumor resection and improving long-term survival. Endoscopic treatment and transanal resection techniques were promising for early-stage tumors but were associated with higher local recurrence rates. Radiotherapy, especially in combination with chemotherapy, played a crucial role in locally advanced cases, improving local control and reducing recurrence risk. Patient data, tumor characteristics, and healthcare system factors were identified as important factors in treatment modality selection. Surgical treatment, specifically TME, remains the recommended standard approach for rectal cancer, providing excellent oncological outcomes. Endoscopic treatment and transanal resection techniques can be considered for selected early-stage cases, while radiotherapy is beneficial for locally advanced tumors. Treatment decisions should be personalized based on patient and tumor characteristics, considering the available resources and expertise within the healthcare system.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:2227-9032
2227-9032
DOI:10.3390/healthcare11162347