Search Results - "Diabetologia"
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Management of hyperglycaemia in type 2 diabetes, 2022. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Published in Diabetologia (01-12-2022)“…The American Diabetes Association and the European Association for the Study of Diabetes convened a panel to update the previous consensus statements on the…”
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Phenotypic characteristics and prognosis of inpatients with COVID-19 and diabetes: the CORONADO study
Published in Diabetologia (01-08-2020)“…Aims/hypothesis Coronavirus disease-2019 (COVID-19) is a life-threatening infection caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)…”
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Global trends in diabetes complications: a review of current evidence
Published in Diabetologia (2019)“…In recent decades, large increases in diabetes prevalence have been demonstrated in virtually all regions of the world. The increase in the number of people…”
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Sex differences in metabolic regulation and diabetes susceptibility
Published in Diabetologia (01-03-2020)“…Gender and biological sex impact the pathogenesis of numerous diseases, including metabolic disorders such as diabetes. In most parts of the world, diabetes is…”
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The mechanisms of action of metformin
Published in Diabetologia (01-09-2017)“…Metformin is a widely-used drug that results in clear benefits in relation to glucose metabolism and diabetes-related complications. The mechanisms underlying…”
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2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Published in Diabetologia (01-02-2020)“…The American Diabetes Association and the European Association for the Study of Diabetes have briefly updated their 2018 recommendations on management of…”
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Gestational diabetes and the risk of cardiovascular disease in women: a systematic review and meta-analysis
Published in Diabetologia (01-06-2019)“…Aims/hypothesis Women who develop gestational diabetes mellitus (GDM) have an elevated lifetime risk of type 2 diabetes mellitus. Recently, a series of studies…”
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SGLT2 inhibitors and mechanisms of cardiovascular benefit: a state-of-the-art review
Published in Diabetologia (01-10-2018)“…Sodium–glucose cotransporter (SGLT)2 inhibitors have been demonstrated to reduce cardiovascular events, particularly heart failure, in cardiovascular outcome…”
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The management of type 1 diabetes in adults. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Published in Diabetologia (01-12-2021)“…The American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) convened a writing group to develop a consensus statement…”
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Fasting blood glucose at admission is an independent predictor for 28-day mortality in patients with COVID-19 without previous diagnosis of diabetes: a multi-centre retrospective study
Published in Diabetologia (01-10-2020)“…Aims/hypothesis Hyperglycaemia is associated with an elevated risk of mortality in community-acquired pneumonia, stroke, acute myocardial infarction, trauma…”
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Metformin: historical overview
Published in Diabetologia (01-09-2017)“…Metformin (dimethylbiguanide) has become the preferred first-line oral blood glucose-lowering agent to manage type 2 diabetes. Its history is linked to Galega…”
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Diabetic cardiomyopathy: a hyperglycaemia- and insulin-resistance-induced heart disease
Published in Diabetologia (01-01-2018)“…Diabetic cardiomyopathy is characterised in its early stages by diastolic relaxation abnormalities and later by clinical heart failure in the absence of…”
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Neurodegeneration in diabetic retinopathy: does it really matter?
Published in Diabetologia (01-09-2018)“…The concept of diabetic retinopathy as a microvascular disease has evolved, in that it is now considered a more complex diabetic complication in which…”
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Canagliflozin reduces inflammation and fibrosis biomarkers: a potential mechanism of action for beneficial effects of SGLT2 inhibitors in diabetic kidney disease
Published in Diabetologia (01-07-2019)“…Aims/hypothesis The sodium–glucose cotransporter 2 (SGLT2) inhibitor canagliflozin slows progression of kidney function decline in type 2 diabetes. The aim of…”
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Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25 year period 1989–2013: a multicentre prospective registration study
Published in Diabetologia (01-03-2019)“…Aims/hypothesis Against a background of a near-universally increasing incidence of childhood type 1 diabetes, recent reports from some countries suggest a…”
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Class effects of SGLT2 inhibitors in mouse cardiomyocytes and hearts: inhibition of Na+/H+ exchanger, lowering of cytosolic Na+ and vasodilation
Published in Diabetologia (01-03-2018)“…Aims/hypothesis Sodium–glucose cotransporter 2 (SGLT2) inhibitors (SGLT2i) constitute a novel class of glucose-lowering (type 2) kidney-targeted agents. We…”
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New insights into the mechanisms of diabetic complications: role of lipids and lipid metabolism
Published in Diabetologia (01-09-2019)“…Diabetes adversely affects multiple organs, including the kidney, eye and nerve, leading to diabetic kidney disease, diabetic retinopathy and diabetic…”
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Hypoxia and hypoxia-inducible factors in diabetes and its complications
Published in Diabetologia (01-04-2021)“…Hypoxia-inducible factors (HIFs) are the key regulators of oxygen homeostasis in response to hypoxia. In diabetes, multiple tissues are hypoxic but adaptive…”
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Sex differences in type 2 diabetes
Published in Diabetologia (01-06-2023)“…The prevalence of type 2 diabetes mellitus is increasing in both sexes, but men are usually diagnosed at a younger age and lower body fat mass than women…”
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Trends and cyclical variation in the incidence of childhood type 1 diabetes in 26 European centres in the 25year period 1989-2013: a multicentre prospective registration study
Published in Diabetologia (01-03-2019)“…Aims/hypothesis: Against a background of a near-universally increasing incidence of childhood type 1 diabetes, recent reports from some countries suggest a…”
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