Search Results - "DiMagno, Stephen G."

Room-Temperature Nucleophilic Aromatic Fluorination: Experimental and Theoretical Studies by Sun, Haoran, DiMagno, Stephen G.

“…Taming the reagent: The use of anhydrous tetrabutylammonium fluoride (TBAFanh) in nucleophilic aromatic substitution reactions, including variants of the…”
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Regiospecific Reductive Elimination from Diaryliodonium Salts by Wang, Bijia, Graskemper, Joseph W, Qin, Linlin, DiMagno, Stephen G

“…Out‐of‐plane steric bulk furnished by a cyclophane substituent on iodine(III) strongly destabilizes the transition state in the reductive elimination from…”
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A Mild and General One-Pot Synthesis of Densely Functionalized Diaryliodonium Salts by Qin, Linlin, Hu, Bao, Neumann, Kiel D., Linstad, Ethan J., McCauley, Katelyenn, Veness, Jordan, Kempinger, Jayson J., DiMagno, Stephen G.

“…Diaryliodonium salts are powerful and widely used arylating agents in organic chemistry. Here we report a scalable synthesis of densely functionalized…”
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Polar Hydrophobicity of Fluorinated Compounds by Biffinger, Justin C, Kim, Hong Woo, DiMagno, Stephen G

“…Fluorine's peculiar property: The CF bond is marked by a peculiar combination of polarity on nonpolarizability (hardness); this imbues fluorinated compounds…”
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Synthesis and Evaluation of 11C-Labeled Triazolones as Probes for Imaging Fatty Acid Synthase Expression by Positron Emission Tomography by Kelly, James M., Jeitner, Thomas M., Waterhouse, Nicole N., Qu, Wenchao, Linstad, Ethan J., Samani, Banafshe, Williams, Clarence, Nikolopoulou, Anastasia, Amor-Coarasa, Alejandro, DiMagno, Stephen G., Babich, John W.

“…Cancer cells require lipids to fulfill energetic, proliferative, and signaling requirements. Even though these cells can take up exogenous fatty acids, the…”
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Reactivities of vinyl azides and their recent applications in nitrogen heterocycle synthesis by Hu, Bao, DiMagno, Stephen G

“…Nitrogen heterocycles are abundant in natural products and pharmaceuticals. An emerging interest among synthetic chemists is to apply vinyl azides as a pivotal…”
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Fluoride relay: a new concept for the rapid preparation of anhydrous nucleophilic fluoride salts from KF by Sun, Haoran, DiMagno, Stephen G

“…Fluoride relay is used to generate exceptionally nucleophilic fluoride reagents from KF on a time scale commensurate with radiotracer synthesis…”
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A Practical, Automated Synthesis of meta-[18F]Fluorobenzylguanidine for Clinical Use by Hu, Bao, Va̅vere, Amy L, Neumann, Kiel D, Shulkin, Barry L, DiMagno, Stephen G, Snyder, Scott E

“…Many neuroendocrine tumors, such as neuroblastoma (NB), arise from neural crest cells of the sympathetic nervous system. This nerve-like phenotype has been…”
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Ligand Fluorination to Optimize Preferential Oxidation of Carbon Monoxide by Water-Soluble Rhodium Porphyrins by Biffinger, Justin C, Uppaluri, ShriHarsha, Sun, Haoran, DiMagno, Stephen G

“…Catalytic, low temperature preferential oxidation (PROX) of carbon monoxide by aqueous…”
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Albumin-Binding PSMA Ligands: Implications for Expanding the Therapeutic Window by Kelly, James M, Amor-Coarasa, Alejandro, Ponnala, Shashikanth, Nikolopoulou, Anastasia, Williams, Jr, Clarence, DiMagno, Stephen G, Babich, John W

“…Despite significant gains in the treatment of metastatic castration-resistant prostate cancer by radioligands targeting prostate-specific membrane antigen…”
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Regioselective Reductive Elimination from Bismuth(V) Compounds for Aryl Transfer to Nucleophiles by Debnath, Shuvra, DiMagno, Stephen G., Wink, Donald J., Lemley, Audra G., Kelly, James M.

“…We demonstrate that regioselective aryl transfer to the nucleophile occurs rapidly under mild conditions via reductive elimination and show that…”
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Anhydrous Tetrabutylammonium Fluoride by Sun, Haoran, DiMagno, Stephen G

“…Tetrabutylammonium fluoride (TBAF) is prepared at low temperature by nucleophilic aromatic substitution of hexafluorobenzene with tetrabutylammonium cyanide…”
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Dual-Target Binding Ligands with Modulated Pharmacokinetics for Endoradiotherapy of Prostate Cancer by Kelly, James M, Amor-Coarasa, Alejandro, Nikolopoulou, Anastasia, Wüstemann, Till, Barelli, Peter, Kim, Dohyun, Williams, Jr, Clarence, Zheng, Xiwei, Bi, Cong, Hu, Bao, Warren, J David, Hage, David S, DiMagno, Stephen G, Babich, John W

“…Prostate-specific membrane antigen (PSMA)-targeted radiotherapy of prostate cancer (PCa) has emerged recently as a promising approach to the treatment of…”
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On the Negligible Impact of Ruffling on the Electronic Spectra of Porphine, Tetramethylporphyrin, and Perfluoroalkylporphyrins by Wertsching, Alan K, Koch, Andrew S, DiMagno, Stephen G

“…In the first part of this paper, the syntheses, structural characterization, molecular modeling, and electronic spectra for planar and nonplanar…”
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Exceptional Electronic Modulation of Porphyrins through meso-Arylethynyl Groups. Electronic Spectroscopy, Electronic Structure, and Electrochemistry of [5,15-Bis[(aryl)ethynyl]- 10,20-diphenylporphinato]zinc(II) Complexes. X-ray Crystal Structures of [5,15-Bis[(4‘-fluorophenyl)ethynyl]- 10,20-diphenylporphinato]zinc(II) and 5,15-Bis[(4‘-methoxyphenyl)ethynyl]-10,20-diphenylporphyrin by LeCours, Steven M, DiMagno, Stephen G, Therien, Michael J

“…A new class of porphyrins in which intervening ethynyl moieties connect aryl groups to the porphyrin 5- and 15-positions is described. The synthesis and…”
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A Trifunctional Theranostic Ligand Targeting Fibroblast Activation Protein-α (FAPα) by Kelly, James M., Jeitner, Thomas M., Ponnala, Shashikanth, Williams, Clarence, Nikolopoulou, Anastasia, DiMagno, Stephen G., Babich, John W.

“…Purpose Fibroblast activation protein-α (FAPα) is uniquely expressed in activated fibroblasts, including cancer-associated fibroblasts that populate tumor…”
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Advanced Fibroblast Activation Protein-Ligand Developments: FAP Imaging Agents: A Review of the Structural Requirements by DiMagno, Stephen G, Babich, John W

“…Fibroblast activation protein-α (FAP) has attracted increasing attention as a selective marker of cancer-associated fibroblasts (CAFs) and more broadly, of…”
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A Method for Detecting Water in Organic Solvents by Sun, Haoran, Wang, Bijia, DiMagno, Stephen G

“…The potent dehydrating ability of difluoro(aryl)-λ3-iodanes is exploited to develop a convenient 19F-NMR-based aquametry method that is more sensitive than…”
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Slow Electron Transfer Rates for Fluorinated Cobalt Porphyrins:  Electronic and Conformational Factors Modulating Metalloporphyrin ET by Sun, Haoran, Smirnov, Valeriy V, DiMagno, Stephen G

“…The electron transfer (ET) properties of a series of closely related cobalt porphyrins,…”
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An Alternative to the Sandmeyer Approach to Aryl Iodides by Hu, Bao, Miller, William H., Neumann, Kiel D., Linstad, Ethan J., DiMagno, Stephen G.

“…Iodoarenes are important synthons for a wide range of organic transformations. Here we report a general strategy to prepare singly iodinated electron‐rich…”
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