Search Results - "DiLisio, James E."

Insulin B-chain hybrid peptides are agonists for T cells reactive to insulin B:9-23 in autoimmune diabetes by Wenzlau, Janet M, DiLisio, James E, Barbour, Gene, Dang, Mylinh, Hohenstein, Anita C, Nakayama, Maki, Delong, Thomas, Baker, Rocky L, Haskins, Kathryn

“…Insulin is considered to be a key antigenic target of T cells in Type 1 Diabetes (T1D) and autoimmune diabetes in the NOD mouse with particular focus on the…”
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Mapping of a hybrid insulin peptide in the inflamed islet β-cells from NOD mice by Wenzlau, Janet M, Peterson, Orion J, Vomund, Anthony N, DiLisio, James E, Hohenstein, Anita, Haskins, Kathryn, Wan, Xiaoxiao

“…There is accumulating evidence that pathogenic T cells in T1D recognize epitopes formed by post-translational modifications of β-cell antigens, including…”
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A model of type 2 diabetes in the guinea pig using sequential diet-induced glucose intolerance and streptozotocin treatment by Podell, Brendan K, Ackart, David F, Richardson, Michael A, DiLisio, James E, Pulford, Bruce, Basaraba, Randall J

“…Type 2 diabetes is a leading cause of morbidity and mortality among noncommunicable diseases, and additional animal models that more closely replicate the…”
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Induction of Antigen-Specific Tolerance in Autoimmune Diabetes with Nanoparticles Containing Hybrid Insulin Peptides by DiLisio, James E, Haskins, Kathryn

“…Autoreactive T cells are thought to orchestrate the onset and progression of autoimmune diabetes. Key cognate antigens of these diabetogenic T cells include…”
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Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection by Butler, Molly, Chotiwan, Nunya, Brewster, Connie D, DiLisio, James E, Ackart, David F, Podell, Brendan K, Basaraba, Randall J, Perera, Rushika, Quackenbush, Sandra L, Rovnak, Joel

“…Dengue virus infection is associated with the upregulation of metabolic pathways within infected cells. This effect is common to infection by a broad array of…”
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295-OR: Mechanisms of Antigen-Specific Immunotherapy following Tolerance Induction to a CD4 Hybrid Insulin Peptide Epitope and the Impact on CD8 T Cell Dysfunction by DILISIO, JAMES E., BAKER, ROCKY L., HASKINS, KATHRYN M.

“…Type 1 diabetes is the culmination of T cell mediated autoimmunity resulting in the destruction of insulin-producing beta cells. Islet-derived hybrid insulin…”
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Establishment of CD1b-restricted immunity to lipid antigens in the pulmonary response to Mycobacterium tuberculosis infection by Harris, Macallister C., Gary, Hadley E., Cooper, Sarah K., Ackart, David F., DiLisio, James E., Basaraba, Randall J., Cheng, Tan-Yun, van Rhijn, Ildiko, Branch Moody, D., Podell, Brendan K.

“…CD1 is an antigen-presenting glycoprotein homologous to MHC I; however, CD1 proteins present lipid rather than peptide antigens. CD1 proteins are well…”
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The Impact of Vitamin A Deficiency on Tuberculosis Progression by Podell, Brendan K, Aibana, Omowunmi, Huang, Chuan-Chin, DiLisio, James E, Harris, Macallister C, Ackart, David F, Armann, Kody, Grover, Alexander, Severe, Patrice, Juste, Marc Antoine Jean, Dupnik, Kathryn, Basaraba, Randall J, Murray, Megan B

“…Abstract Background Although previous studies have shown that vitamin A deficiency is associated with incident tuberculosis (TB) disease, the direction of the…”
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Tolerogenic Delivery of a Hybrid Insulin Peptide Markedly Prolongs Islet Graft Survival in the NOD Mouse by Jamison, Braxton L, DiLisio, James E, Beard, K Scott, Neef, Tobias, Bradley, Brenda, Goodman, Jessica, Gill, Ronald G, Miller, Stephen D, Baker, Rocky L, Haskins, Kathryn

“…The induction of antigen (Ag)-specific tolerance and replacement of islet β-cells are major ongoing goals for the treatment of type 1 diabetes (T1D). Our group…”
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Metformin enhances protection in guinea pigs chronically infected with Mycobacterium tuberculosis by Frenkel, Jessica D. Haugen, Ackart, David F., Todd, Alexandra K., DiLisio, James E., Hoffman, Siana, Tanner, Samantha, Kiran, Dilara, Murray, Megan, Chicco, Adam, Obregón-Henao, Andrés, Podell, Brendan K., Basaraba, Randall J.

“…Tuberculosis (TB) is a chronic inflammatory disease that is often associated with alterations in systemic and cellular metabolism that resolves following…”
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1728-P: Inhibition of PKC-Theta in Prediabetic NOD Mice Prevents Diabetes Onset and Increases Regulatory CD4 T Cells in a Subset of Animals by DILISIO, JAMES E., MISHKIN, NOAH, PODELL, BRENDAN

“…The novel PKC isoform, PKC-theta, is particularly enriched in T lymphocyte populations, serving a critical role in signal transduction after CD3/CD28 T cell…”
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Induction of tolerance to a CD4 T cell hybrid insulin peptide epitope prolongs islet graft survival and suppresses autoreactive CD8 T cells by DiLisio, James E, Jamison, Braxton L, Neef, Tobias, Miller, Stephen D, Baker, Rocky, Haskins, Kathryn

“…Abstract Autoreactive T cells are thought to drive autoimmune diabetes by recognizing beta cell-derived peptide antigens. We previously discovered that hybrid…”
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Suppression of IGRP-specific CD8 T cells following induction of tolerance to a Hybrid Insulin Peptide CD4 neoepitope by DiLisio, James E, Reyes, Kaitlin, Beard, K. Scott, Neef, Tobias, Miller, Stephen D, Baker, Rocky L., Haskins, Kathryn

“…Abstract An autoimmune-mediated death of insulin-producing beta cells, orchestrated by effector CD4 and CD8 T cells that recognize islet antigens, results in…”
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Maryland: A Geography by Earle, Carville

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