Search Results - "DiGiovanni, Laura F."

Upregulated pexophagy limits the capacity of selective autophagy by Germain, Kyla, So, Raphaella W. L., DiGiovanni, Laura F., Watts, Joel C., Bandsma, Robert H. J., Kim, Peter K.

“…Selective autophagy is an essential process to maintain cellular homeostasis through the constant recycling of damaged or superfluous components. Over a dozen…”
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Glycogen synthase downregulation rescues the amylopectinosis of murine RBCK1 deficiency by Nitschke, Silvia, Sullivan, Mitchell A, Mitra, Sharmistha, Marchioni, Charlotte R, Lee, Jennifer P Y, Smith, Brandon H, Ahonen, Saija, Wu, Jun, Chown, Erin E, Wang, Peixiang, Petković, Sara, Zhao, Xiaochu, DiGiovanni, Laura F, Perri, Ami M, Israelian, Lori, Grossman, Tamar R, Kordasiewicz, Holly, Vilaplana, Francisco, Iwai, Kazuhiro, Nitschke, Felix, Minassian, Berge A

“…Longer glucan chains tend to precipitate. Glycogen, by far the largest mammalian glucan and the largest molecule in the cytosol with up to 55 000 glucoses,…”
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Huntingtin N17 domain is a reactive oxygen species sensor regulating huntingtin phosphorylation and localization by DiGiovanni, Laura F, Mocle, Andrew J, Xia, Jianrun, Truant, Ray

“…The N17 domain of the huntingtin protein is post-translationally modified and is the master regulator of huntingtin intracellular localization. In Huntington's…”
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Arf1-PI4KIIIβ positive vesicles regulate PI(3)P signaling to facilitate lysosomal tubule fission by Boutry, Maxime, DiGiovanni, Laura F, Demers, Nicholas, Fountain, Aaron, Mamand, Sami, Botelho, Roberto J, Kim, Peter K

“…Formation and fission of tubules from autolysosomes, endolysosomes, or phagolysosomes are required for lysosome reformation. However, the mechanisms governing…”
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Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling by Cabral-Dias, Rebecca, Lucarelli, Stefanie, Zak, Karolina, Rahmani, Sadia, Judge, Gurjeet, Abousawan, John, DiGiovanni, Laura F, Vural, Dafne, Anderson, Karen E, Sugiyama, Michael G, Genc, Gizem, Hong, Wanjin, Botelho, Roberto J, Fairn, Gregory D, Kim, Peter K, Antonescu, Costin N

“…The epidermal growth factor (EGF) receptor (EGFR) controls many aspects of cell physiology. EGF binding to EGFR elicits the membrane recruitment and activation…”
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