Search Results - "Di Stefano, Antonino"

Elevated serum IgE, oral corticosteroid dependence and IL-17/22 expression in highly neutrophilic asthma by Bullone, Michela, Carriero, Vitina, Bertolini, Francesca, Folino, Anna, Mannelli, Alessandro, Di Stefano, Antonino, Gnemmi, Isabella, Torchio, Roberto, Ricciardolo, Fabio L M

“…Information on the clinical traits associated with bronchial neutrophilia in asthma is scant, preventing its recognition and adequate treatment. We aimed to…”
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Bacterial and viral infections and related inflammatory responses in chronic obstructive pulmonary disease by D'Anna, Silvestro Ennio, Maniscalco, Mauro, Cappello, Francesco, Carone, Mauro, Motta, Andrea, Balbi, Bruno, Ricciardolo, Fabio L. M., Caramori, Gaetano, Di Stefano, Antonino

“…In chronic obstructive pulmonary disease (COPD) patients, bacterial and viral infections play a relevant role in worsening lung function and, therefore, favour…”
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Identification of IL-17F/frequent exacerbator endotype in asthma by Ricciardolo, Fabio L.M., MD, PhD, Sorbello, Valentina, PhD, Folino, Anna, PhD, Gallo, Fabio, MSc, Massaglia, Gian Mario, MD, Favatà, Gabriella, MD, Conticello, Salvatore, MD, Vallese, Davide, PhD, Gani, Federica, MD, Malerba, Mario, MD, Folkerts, Gert, PhD, Rolla, Giovanni, MD, Profita, Mirella, PhD, Mauad, Thais, PhD, Di Stefano, Antonino, PhD, Ciprandi, Giorgio, MD

“…Background Severe asthma might be associated with overexpression of T h 17 cytokines, which induce neutrophil recruitment via neutrophil-mobilizing cytokines…”
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Conjunctival transcriptome analysis reveals the overexpression of multiple pattern recognition receptors in vernal keratoconjunctivitis by Leonardi, Andrea, Daull, Philippe, Garrigue, Jean-Sébastien, Cavarzeran, Fabiano, Docquier, Mylène, Di Stefano, Antonino, Tarricone, Elena, Brun, Paola

“…Vernal keratoconjunctivitis (VKC) is a chronic, potentially blinding ocular allergic disease affecting children with uncertain pathogenic mechanisms. To…”
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Clinical Characterization of the Frequent Exacerbator Phenotype in Asthma by Sprio, Andrea Elio, Carriero, Vitina, Levra, Stefano, Botto, Carlotta, Bertolini, Francesca, Di Stefano, Antonino, Maniscalco, Mauro, Ciprandi, Giorgio, Ricciardolo, Fabio Luigi Massimo

“…Background: Asthma exacerbation is episodic worsening of respiratory symptoms in conjunction with the deterioration of lung function, which may occur…”
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Wharton’s Jelly Mesenchymal Stem Cells as Candidates for Beta Cells Regeneration: Extending the Differentiative and Immunomodulatory Benefits of Adult Mesenchymal Stem Cells for the Treatment of Type 1 Diabetes by Anzalone, Rita, Lo Iacono, Melania, Loria, Tiziana, Di Stefano, Antonino, Giannuzzi, Pantaleo, Farina, Felicia, La Rocca, Giampiero

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CD8+ T-Lymphocytes in Peripheral Airways of Smokers with Chronic Obstructive Pulmonary Disease by SAETTA, MARINA, Di STEFANO, ANTONINO, TURATO, GRAZIELLA, FACCHINI, FABRIZIO M, CORBINO, LAURA, MAPP, CRISTINA E, MAESTRELLI, PIERO, CIACCIA, ADALBERTO, FABBRI, LEONARDO M

“…To investigate whether the inflammatory process in peripheral airways is different in smokers who develop symptoms of chronic bronchitis and chronic airflow…”
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A microRNA-21-mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis by Kim, Richard Y, Sunkara, Krishna P, Bracke, Ken R, Jarnicki, Andrew G, Donovan, Chantal, Hsu, Alan C, Ieni, Antonio, Beckett, Emma L, Galvão, Izabela, Wijnant, Sara, Ricciardolo, Fabio Lm, Di Stefano, Antonino, Haw, Tatt Jhong, Liu, Gang, Ferguson, Angela L, Palendira, Umamainthan, Wark, Peter A, Conickx, Griet, Mestdagh, Pieter, Brusselle, Guy G, Caramori, Gaetano, Foster, Paul S, Horvat, Jay C, Hansbro, Philip M

“…Chronic obstructive pulmonary disease (COPD) is the third leading cause of morbidity and death worldwide. Inhalation of cigarette smoke (CS) is the major cause…”
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Hsp10 nuclear localization and changes in lung cells response to cigarette smoke suggest novel roles for this chaperonin by Corrao, Simona, Anzalone, Rita, Lo Iacono, Melania, Corsello, Tiziana, Di Stefano, Antonino, D'Anna, Silvestro Ennio, Balbi, Bruno, Carone, Mauro, Sala, Anna, Corona, Davide, Timperio, Anna Maria, Zolla, Lello, Farina, Felicia, Conway de Macario, Everly, Macario, Alberto J. L., Cappello, Francesco, La Rocca, Giampiero

“…Heat-shock protein (Hsp)10 is the co-chaperone for Hsp60 inside mitochondria, but it also resides outside the organelle. Variations in its levels and…”
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Phenotype overlap in the natural history of asthma by Ricciardolo, Fabio L M, Guida, Giuseppe, Bertolini, Francesca, Di Stefano, Antonino, Carriero, Vitina

“…The heterogeneity of asthma makes it challenging to unravel the pathophysiologic mechanisms of the disease. Despite the wealth of research identifying diverse…”
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Bronchial inflammation and bacterial load in stable COPD is associated with TLR4 overexpression by Di Stefano, Antonino, Ricciardolo, Fabio L M, Caramori, Gaetano, Adcock, Ian M, Chung, Kian Fan, Barnes, Peter J, Brun, Paola, Leonardi, Andrea, Andò, Filippo, Vallese, Davide, Gnemmi, Isabella, Righi, Luisella, Cappello, Francesco, Balbi, Bruno

“…Toll-like receptors (TLRs) and nucleotide-binding oligomerisation domain (NOD)-like receptors (NLRs) are two major forms of innate immune sensors but their…”
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Correlation of matrix‐related airway remodeling and bradykinin B1 receptor expression with fixed airflow obstruction in severe asthma by Bertolini, Francesca, Carriero, Vitina, Bullone, Michela, Sprio, Andrea Elio, Defilippi, Ilaria, Sorbello, Valentina, Gani, Federica, Di Stefano, Antonino, Ricciardolo, Fabio Luigi Massimo

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Inhibition of Pro-Fibrotic Molecules Expression in Idiopathic Pulmonary Fibrosis-Derived Lung Fibroblasts by Lactose-Modified Hyaluronic Acid Compounds by Donato, Alice, Di Stefano, Antonino, Freato, Nadia, Bertocchi, Laura, Brun, Paola

“…Idiopathic pulmonary fibrosis (IPF) is a chronic inflammatory and fibrotic pathological condition with undefined effective therapies and a poor prognosis,…”
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Role of ATG4 Autophagy-Related Protein Family in the Lower Airways of Patients with Stable COPD by Nucera, Francesco, Di Stefano, Antonino, Ricciardolo, Fabio Luigi Massimo, Gnemmi, Isabella, Pizzimenti, Cristina, Monaco, Francesco, Tuccari, Giovanni, Caramori, Gaetano, Ieni, Antonio

“…Autophagy is a complex physiological pathway mediating homeostasis and survival of cells degrading damaged organelles and regulating their recycling…”
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Upregulation of Notch Signaling and Cell-Differentiation Inhibitory Transcription Factors in Stable Chronic Obstructive Pulmonary Disease Patients by Di Stefano, Antonino, Gnemmi, Isabella, Rosani, Umberto, Maniscalco, Mauro, D'Anna, Silvestro Ennio, Brun, Paola, Carriero, Vitina, Bertolini, Francesca, Balbi, Bruno, Ricciardolo, Fabio Luigi Massimo

“…Notch signaling is involved in the prevention of cell differentiation and cell fate in various organs, including the lungs. We aimed to determine the…”
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The Anti-Inflammatory Effect of Lactose-Modified Hyaluronic Acid Molecules on Primary Bronchial Fibroblasts of Smokers by Donato, Alice, Fontana, Federico, Venerando, Rina, Di Stefano, Antonino, Brun, Paola

“…The progression of smoking-related diseases is characterized by macrophage-mediated inflammation, which is responsible for an increased expression of…”
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Cytokine inhibition in the treatment of COPD by Caramori, Gaetano, Adcock, Ian M, Di Stefano, Antonino, Chung, Kian Fan

“…Cytokines play an important part in many pathobiological processes of chronic obstructive pulmonary disease (COPD), including the chronic inflammatory process,…”
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Muscarinic receptor M3 contributes to vascular and neural growth factor up‐regulation in severe asthma by Folino, Anna, Carriero, Vitina, Bullone, Michela, Bertolini, Francesca, Di Stefano, Antonino, Profita, Mirella, Balbi, Bruno, Pieper, Michael, Ricciardolo, Fabio L. M.

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Decreased humoral immune response in the bronchi of rapid decliners with chronic obstructive pulmonary disease by Di Stefano, Antonino, Dossena, Francesca, Gnemmi, Isabella, D'Anna, Silvestro Ennio, Brun, Paola, Balbi, Bruno, Piraino, Alessio, Spanevello, Antonio, Nucera, Francesco, Carriero, Vitina, Bertolini, Francesca, Maniscalco, Mauro, Adcock, Ian M, Caramori, Gaetano, Ricciardolo, Fabio L. M

“…Abstract Background Identification of COPD patients with a rapid decline in FEV1 is of particular interest for prognostic and therapeutic reasons. Objective To…”
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Impact of Galectin-3 Circulating Levels on Frailty in Elderly Patients with Systolic Heart Failure by Komici, Klara, Gnemmi, Isabella, Bencivenga, Leonardo, Vitale, Dino Franco, Rengo, Giuseppe, Di Stefano, Antonino, Eleuteri, Ermanno

“…Background: Heart Failure (HF), a leading cause of morbidity and mortality, represents a relevant trigger for the development of frailty in the elderly…”
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