Search Results - "Di Michele, M"

Proteomics to unravel platelet-related diseases and identify novel anti-platelet drugs by Di Michele, M, Van Geet, C, Freson, K

“…Blood platelets play a fundamental role in primary haemostasis and wound repair, but are also involved in several thrombotic and bleeding disorders for which…”
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Platelet Gs hypofunction and abnormal morphology resulting from a heterozygous RGS2 mutation by NOÉ, L., DI MICHELE, M., GIETS, E., THYS, C., WITTEVRONGEL, C., DE VOS, R., OVERBERGH, L., WAELKENS, E., JAEKEN, J., VAN GEET, C., FRESON, K.

“…Background: Regulator of G‐protein signaling (RGS) 2 negatively regulates Gs signaling by inhibiting the activation of adenylyl cyclase (AC). RGS2 mRNA…”
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Limited Proteolysis Combined with Stable Isotope Labeling Reveals Conformational Changes in Protein (Pseudo)kinases upon Binding Small Molecules by Di Michele, Michela, Stes, Elisabeth, Vandermarliere, Elien, Arora, Rohit, Astorga-Wells, Juan, Vandenbussche, Jonathan, van Heerde, Erika, Zubarev, Roman, Bonnet, Pascal, Linders, Joannes T. M, Jacoby, Edgar, Brehmer, Dirk, Martens, Lennart, Gevaert, Kris

“…Likely due to conformational rearrangements, small molecule inhibitors may stabilize the active conformation of protein kinases and paradoxically promote…”
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Proteomic analysis of platelet N -glycoproteins in PMM2-CDG patients by de la Morena-Barrio, M.E, Di Michele, M, Lozano, M.L, Rivera, J, Pérez-Dueñas, B, Altisent, C, Sevivas, T, Vicente, V, Jaeken, J, Freson, K, Corral, J

“…Abstract PMM2-CDG, the most frequent congenital disorder of N- glycosylation, is an autosomal recessive disease with a multisystem presentation. PMM2-CDG…”
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Severe and moderate haemophilia A and B in US females by Di Michele, D. M., Gibb, C., Lefkowitz, J. M., Ni, Q., Gerber, L. M., Ganguly, A.

“…Summary Haemophilia A and B are rare X‐lined hemorrhagic disorders that typically affect men. Women are usually asymptomatic carriers, but may be symptomatic…”
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integrated approach to the characterization of two autochthonous lentil (Lens culinaris) landraces of Molise (south-central Italy) by Scippa, G.S, Trupiano, D, Rocco, M, Viscosi, V, Di Michele, M, D'Andrea, A, Chiatante, D

“…Plant biodiversity must be safeguarded because it constitutes a resource of genes that may be used, for instance, in breeding programs. Lentil (Lens culinaris…”
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Improved reactivity of hepatitis C virus core protein epitopes in a conformational antigen-presenting system by Buratti, E, Di Michele, M, Song, P, Monti-Bragadin, C, Scodeller, E A, Baralle, F E, Tisminetzky, S G

“…Recent studies have identified several epitopes in the N-terminal portion of the nucleocapsid protein which are predominantly recognized by sera of patients…”
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Dormancy of Medicago marina (L.) seed by Scippa, G.S., Petrollini, E., Trupiano, D., Rocco, M., Falco, G., Di Michele, M., Chiatante, D.

“…► Medicago marina seed dormancy is due to the presence of a hard seed coat. ► Seed-coat dormancy is removed by scarification and freezing, but not by heating…”
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Plant species delimitation: A comparison of morphological and molecular markers by Duminil, J., Di Michele, M.

“…Species delimitation is fundamental in many areas of biology. Despite its importance, there is no agreement on criteria for species delimitation mostly due to…”
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Immune tolerance induction in haemophilia: evidence and the way forward by DI MICHELE, D. M.

“…Given the inhibitor‐associated morbidity resulting from limited effective treatment options, antibody eradication is the ultimate goal of inhibitor management…”
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PCR ribotyping for characterizing Salmonella isolates of different serotypes by Lagatolla, C. (Universita degli Studi Trieste, Italy.), Dolzani, L, Tonin, E, Lavenia, A, Di Michele, M, Tommasini, T, Monti-Bragadin, C

“…The 16S-23S intergenic spacer region in 218 strains of Salmonella isolated from four Italian hospitals during the period from 1977 to 1994 was analyzed by PCR…”
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Homozygosity for aquaporin 7 G264V in three unrelated children with hyperglyceroluria and a mild platelet secretion defect by Goubau, Christophe, Jaeken, Jaak, Levtchenko, Elena N, Thys, Chantal, Di Michele, Michela, Martens, Geert A, Gerlo, Erik, De Vos, Rita, Buyse, Gunnar M, Goemans, Nathalie, Van Geet, Chris, Freson, Kathleen

“…Purpose: Aquaporin 7 (AQP7) belongs to the aquaglyceroporin family, which transports glycerol and water. AQP7-deficient mice develop obesity, insulin…”
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histone-like protein H1-S and the response of tomato leaves to water deficit by Scippa, G.S, Di Michele, D, Onelli, E, Patrignani, G, Chiatante, D, Bray, E.A

“…Linker histone protein variants are expressed in different tissues, at various developmental stages or induced by specific environmental conditions in many…”
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Immune tolerance: a synopsis of the international experience by Lee, C. A., Kessler, C. M., Varon, D., Martinowitz, U., Heim, M., DI MICHELE, D. M.

“…Because of the increased morbidity and cost of care associated with inhibitor development, immune tolerance therapy (ITT) is of crucial value in the care of…”
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Prior Publication Productivity, Grant Percentile Ranking, and Topic-Normalized Citation Impact of NHLBI Cardiovascular R01 Grants by Kaltman, Jonathan R, Evans, Frank J, Danthi, Narasimhan S, Wu, Colin O, DiMichele, Donna M, Lauer, Michael S

“…RATIONALE:We previously demonstrated absence of association between peer-review–derived percentile ranking and raw citation impact in a large cohort of…”
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response of Spartium junceum roots to slope: anchorage and gene factors by Scippa, G.S, Di Michele, M, Di Iorio, A, Costa, A, Lasserre, B, Chiatante, D

“…BACKGROUND AND AIMS: Plant anchorage is governed by complex, finely regulated mechanisms that occur at a morphological, architectural and anatomical level…”
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A proteomic analysis of Spanish broom ( Spartium junceum L.) root growing on a slope condition by Di Michele, Michela, Chiatante, Donato, Plomion, Christophe, Scippa, Gabriella Stefania

“…The stability of plants growing on a slope may be affected by factors that tend to uproot the plant. To avoid uprooting, roots undergo complex, finely…”
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Finally, Cinderella goes to the party by Di Mauro, Michele, MD

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Venoarterial Extracorporeal Membrane Oxygenation for Acute Fulminant Myocarditis in Adult Patients: A 5-Year Multi-Institutional Experience by Lorusso, Roberto, MD, PhD, Centofanti, Paolo, MD, Gelsomino, Sandro, MD, PhD, Barili, Fabio, MD, PhD, Di Mauro, Michele, MD, Orlando, Parise, MS, Botta, Luca, MD, Milazzo, Filippo, MD, Actis Dato, Guglielmo, MD, Casabona, Riccardo, MD, Casali, Giovanni, MD, Musumeci, Francesco, MD, De Bonis, Michele, MD, Zangrillo, Alberto, MD, Alfieri, Ottavio, MD, Pellegrini, Carlo, MD, Mazzola, Sandro, MD, Coletti, Giuseppe, MD, Vizzardi, Enrico, MD, Bianco, Roberto, MD, Gerosa, Gino, MD, Massetti, Massimo, MD, PhD, Caldaroni, Federica, MD, Pilato, Emanuele, MD, Pacini, Davide, MD, Di Bartolomeo, Roberto, MD, Marinelli, Giuseppe, MD, Sponga, Sandro, MD, PhD, Livi, Ugolino, MD, Mauro, Rinaldi, MD, Mariscalco, Giovanni, MD, PhD, Beghi, Cesare, MD, Miceli, Antonio, MD, PhD, Glauber, Mattia, MD, Pappalardo, Federico, MD, Russo, Claudio Francesco, MD

“…Background Acute fulminant myocarditis (AFM) may represent a life-threatening event, characterized by rapidly progressive cardiac compromise that ultimately…”
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Use of PCR-Ribotyping for the characterisation of Salmonella by Dolzani, L, Di Michele, M, Monti-Bragadin, C

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