Search Results - "Di Martino, M T"

Promises and challenges of MicroRNA-based treatment of multiple myeloma by Tagliaferri, P, Rossi, M, Di Martino, M T, Amodio, N, Leone, E, Gulla, A, Neri, A, Tassone, P

“…MicroRNAs (miRNAs) recently emerged with a key role in multiple myeloma (MM) pathophysiology and are considered important regulators of MM cell growth and…”
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Mouse models as a translational platform for the development of new therapeutic agents in multiple myeloma by Tassone, P, Neri, P, Burger, R, Di Martino, M T, Leone, E, Amodio, N, Caraglia, M, Tagliaferri, P

“…Mouse models of multiple myeloma (MM) are basic tools for translational research and play a fundamental role in the development of new therapeutics against…”
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A unique three-dimensional SCID-polymeric scaffold (SCID-synth-hu) model for in vivo expansion of human primary multiple myeloma cells by Calimeri, T, Battista, E, Conforti, F, Neri, P, Di Martino, M T, Rossi, M, Foresta, U, Piro, E, Ferrara, F, Amorosi, A, Bahlis, N, Anderson, K C, Munshi, N, Tagliaferri, P, Causa, F, Tassone, P

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Selective targeting of IRF4 by synthetic microRNA-125b-5p mimics induces anti-multiple myeloma activity in vitro and in vivo by Morelli, E, Leone, E, Cantafio, M E Gallo, Di Martino, M T, Amodio, N, Biamonte, L, Gullà, A, Foresta, U, Pitari, M R, Botta, C, Rossi, M, Neri, A, Munshi, N C, Anderson, K C, Tagliaferri, P, Tassone, P

“…Interferon regulatory factor 4 (IRF4) is an attractive therapeutic target in multiple myeloma (MM). We here report that expression of IRF4 mRNA inversely…”
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MiR-29b antagonizes the pro-inflammatory tumor-promoting activity of multiple myeloma-educated dendritic cells by Botta, C, Cucè, M, Pitari, M R, Caracciolo, D, Gullà, A, Morelli, E, Riillo, C, Biamonte, L, Gallo Cantafio, M E, Prabhala, R, Mignogna, C, Di Vito, A, Altomare, E, Amodio, N, Di Martino, M T, Correale, P, Rossi, M, Giordano, A, Munshi, N C, Tagliaferri, P, Tassone, P

“…Dendritic cells (DCs) have a key role in regulating tumor immunity, tumor cell growth and drug resistance. We hypothesized that multiple myeloma (MM) cells…”
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Psychrophilic superoxide dismutase from Pseudoalteromonas haloplanktis: biochemical characterization and identification of a highly reactive cysteine residue by Castellano, I., Di Maro, A., Ruocco, M.R., Chambery, A., Parente, A., Di Martino, M.T., Parlato, G., Masullo, M., De Vendittis, E.

“…A psychrophilic superoxide dismutase (SOD) has been characterized from the Antarctic eubacterium Pseudoalteromonas haloplanktis ( Ph). PhSOD is a homodimeric…”
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miR-29b sensitizes multiple myeloma cells to bortezomib-induced apoptosis through the activation of a feedback loop with the transcription factor Sp1 by Amodio, N, Di Martino, M T, Foresta, U, Leone, E, Lionetti, M, Leotta, M, Gullà, A M, Pitari, M R, Conforti, F, Rossi, M, Agosti, V, Fulciniti, M, Misso, G, Morabito, F, Ferrarini, M, Neri, A, Caraglia, M, Munshi, N C, Anderson, K C, Tagliaferri, P, Tassone, P

“…MicroRNAs (miRNAs) with tumor-suppressor potential might have therapeutic applications in multiple myeloma (MM) through the modulation of still undiscovered…”
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Development and validation of a bioanalytical method for quantification of LNA-i-miR-221, a 13-mer oligonucleotide, in rat plasma using LC–MS/MS by Franzoni, S., Vezzelli, A., Turtoro, A., Solazzo, L., Greco, A., Tassone, P., Di Martino, M.T., Breda, M.

“…•An ion-pair reversed-phase LC–MS/MS method for the determination of LNA-i-miR-221, a 13-mer oligonucleotide, in rat plasma was developed and…”
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A gene expression inflammatory signature specifically predicts multiple myeloma evolution and patients survival by Botta, C, Di Martino, M T, Ciliberto, D, Cucè, M, Correale, P, Rossi, M, Tagliaferri, P, Tassone, P

“…Multiple myeloma (MM) is closely dependent on cross-talk between malignant plasma cells and cellular components of the inflammatory/immunosuppressive bone…”
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P341: A NOVEL BISPECIFIC T CELL ENGAGER (UMG2‐CD3) IS EFFECTIVE AGAINST CORTICAL‐DERIVED ACUTE LYMPHOBLASTIC LEUKEMIA by Riillo, C., Caracciolo, D., Grillone, K., Polerà, N., Tuccillo, F. M., Bonelli, P., Juli, G., Ascrizzi, S., Scionti, F., Arbitrio, M., Lopreiato, M., Siciliano, M. A., Sestito, S., Talarico, G., Galea, E., Galati, M. C., Rossi, M., Ballerini, A., Gentile, M., Di Martino, M. T., Tagliaferri, P., Tassone, P.

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2150The modulation of miR-129-3p levels in coronary thrombi after primary PCI discloses a novel potential mechanism underlying the no reflow phenomenon by De Rosa, S, Iaconetti, C, Piccione, V, Di Martino, M T, Tamme, L, Polimeni, A, Sabatino, J, Sorrentino, S, Mazziotti, A, Gareri, C, Tassone, P, Indolfi, C

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Correction: Targeting miR21 Inhibits In Vitro and In Vivo Multiple Myeloma Cell Growth

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From target therapy to miRNA therapeutics of human multiple myeloma: theoretical and technological issues in the evolving scenario by Rossi, Marco, Amodio, Nicola, Di Martino, M T, Caracciolo, Daniele, Tagliaferri, Pierosandro, Tassone, Pierfrancesco

“…The progress in the understanding of biological events underlying multiple myeloma (MM) development and progression has allowed the design of molecularly…”
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A peroxisome proliferator‐activated receptor gamma (PPARG) polymorphism is associated with zoledronic acid‐related osteonecrosis of the jaw in multiple myeloma patients: analysis by DMET microarray profiling by Di Martino, Maria T., Arbitrio, Mariamena, Guzzi, Pietro H., Leone, Emanuela, Baudi, Francesco, Piro, Eugenio, Prantera, Tullia, Cucinotto, Iole, Calimeri, Teresa, Rossi, Marco, Veltri, Pierangelo, Cannataro, Mario, Tagliaferri, Pierosandro, Tassone, Pierfrancesco

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Differential transcriptional response to cisplatinum in BRCA1-defective versus BRCA1-reconstituted breast cancer cells by microarrays by Di Martino, MT, Ventura, M, Guzzi, PH, Pietragalla, A, Neri, P, Bulotta, A, Calimeri, T, Barbieri, V, Caraglia, M, Veltri, P, Cannataro, M, Tassone, P, Tagliaferri, P

“…Abstract Abstract #5062 BRCA1-related breast cancer represents a distinct clinical entity characterized by basal-like molecular phenotype. HCC1937 is a…”
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EDTA is essential to recover lead from dried blood spots on filter paper by Di Martino, Maria T., Michniewicz, Andzelika, Martucci, Maria, Parlato, Giuseppe

“…Residual dried blood spots (DBSs) on filter paper from neonatal screening have been proposed as samples for population survey of lead contamination. We have…”
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Areas in Calabria with an elevated incidence of congenital hypothyroidism and iodine content of drinking water by Di Martino, M T, Martucci, M, Filippelli, P, Scalzo, R, Parlato, G

“…The screening of 128,442 newborns, carried out in our laboratory from 1/1/1991 to 31/12/1996, detected 51 cases of congenital hypothyroidism (CH). Due to a 98%…”
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