Search Results - "Di Marco, Marika Pasternyk"

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  1. 1
    A population pharmacokinetic-metabolism model for individualizing ciprofloxacin therapy in ophthalmology

    A population pharmacokinetic-metabolism model for individualizing ciprofloxacin therapy in ophthalmology by Di Marco, Marika Pasternyk, Chen, John, Wainer, Irving W, Ducharme, Murray P

    Published in Therapeutic drug monitoring (01-08-2004)
    “…The purpose of this study was to construct a population pharmacokinetic (PK) metabolism (MB) model to describe ciprofloxacin (C) concentrations in plasma and…”
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  2. 2
    New insights into the pharmacokinetics and metabolism of (R, S)-ifosfamide in cancer patients using a population pharmacokinetic-metabolism model

    New insights into the pharmacokinetics and metabolism of (R, S)-ifosfamide in cancer patients using a population pharmacokinetic-metabolism model by DI MARCO, M. P, WAINER, I. W, GRANVIL, C. L, BATIST, G, DUCHARME, M. P

    Published in Pharmaceutical research (01-06-2000)
    “…To describe the pharmacokinetics of R- and S-Ifosfamide (IFF), and their respective 2 and 3 N-dechloroethylated (DCE) metabolites (R2-, R3-, S2, S3-DCE-IFF) in…”
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  3. 3
    The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: The role of gut CYP3A and P-glycoprotein

    The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: The role of gut CYP3A and P-glycoprotein by Di Marco, Marika Pasternyk, Edwards, David J, Wainer, Irving W, Ducharme, Murray P

    Published in Life sciences (1973) (26-07-2002)
    “…The objective of this study was to determine the effects of grapefruit juice and seville orange juice on dextromethorphan (DM) pharmacokinetics. Eleven healthy…”
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  4. 4
    On-line deconjugation of chloramphenicol-β-d-glucuronide on an immobilized β-glucuronidase column

    On-line deconjugation of chloramphenicol-β-d-glucuronide on an immobilized β-glucuronidase column by Pasternyk (Di Marco), Marika, Ducharme, Murray P., Descorps, Vincent, Felix, Guy, Wainer, Irving W.

    Published in Journal of Chromatography A (01-12-1998)
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  5. 5
    On-line deconjugation of chloramphenicol-β- d-glucuronide on an immobilized β-glucuronidase column : Application to the direct analysis of urine samples

    On-line deconjugation of chloramphenicol-β- d-glucuronide on an immobilized β-glucuronidase column : Application to the direct analysis of urine samples by Pasternyk (Di Marco), Marika, Ducharme, Murray P., Descorps, Vincent, Felix, Guy, Wainer, Irving W.

    Published in Journal of Chromatography A (18-12-1998)
    “…An immobilized HPLC column has been developed for the on-line deconjugation of β-glucuronides. The enzymatic activity of this column has been previously…”
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  6. 6
    On-line deconjugation of glucuronides using an immobilized enzyme reactor based upon β-glucuronidase

    On-line deconjugation of glucuronides using an immobilized enzyme reactor based upon β-glucuronidase by Pasternyk Di Marco, Marika, Felix, Guy, Descorps, Vincent, Ducharme, Murray P, Wainer, Irving W

    “…An immobilized enzyme reactor based upon β-glucuronidase (BG–IMER) has been developed for the on-line deconjugation of substrates. The activity of the BG–IMER…”
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