Search Results - "Di Marco, Giovana S"
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The Soluble VEGF Receptor sFlt1 Contributes to Endothelial Dysfunction in CKD
Published in Journal of the American Society of Nephrology (01-10-2009)“…Endothelial dysfunction contributes to the increased cardiovascular risk that accompanies CKD. We hypothesized that the soluble VEGF receptor 1 (sFlt-1), a…”
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2
Fibroblast growth factor 23 directly targets hepatocytes to promote inflammation in chronic kidney disease
Published in Kidney international (01-11-2016)“…Patients with chronic kidney disease (CKD) develop increased levels of the phosphate-regulating hormone, fibroblast growth factor (FGF) 23, that are associated…”
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3
The Endothelial Glycocalyx as a Target of Excess Soluble Fms-like Tyrosine Kinase-1
Published in International journal of molecular sciences (01-03-2023)“…Soluble fms-like tyrosine kinase-1 (sFlt-1) is a secreted protein that binds heparan sulfate expressed on the endothelial glycocalyx (eGC). In this paper we…”
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4
Downregulation of the antioxidant protein peroxiredoxin 2 contributes to angiotensin II–mediated podocyte apoptosis
Published in Kidney international (01-11-2011)“…Podocytes have a significant role in establishing selective permeability of the glomerular filtration barrier. Sustained renin–angiotensin–aldosterone system…”
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Circulating endothelial progenitor cells in kidney transplant patients
Published in PloS one (08-09-2011)“…Kidney transplantation (RTx) leads to amelioration of endothelial function in patients with advanced renal failure. Endothelial progenitor cells (EPCs) may…”
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6
Circulating Soluble Fms-like Tyrosine Kinase in Renal Diseases Other than Preeclampsia
Published in Journal of the American Society of Nephrology (01-08-2021)“…Soluble Fms-like tyrosine kinase (sFlt-1/sVEGFR1) is a naturally occurring antagonist of vascular endothelial growth factor (VEGF). Despite being a secreted,…”
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Cardioprotective effect of calcineurin inhibition in an animal model of renal disease
Published in European heart journal (01-08-2011)“…Aims Chronic kidney disease is directly associated with cardiovascular complications. Heart remodelling, including fibrosis, hypertrophy, and decreased…”
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Increased soluble fms-like tyrosine kinase 1 after ischemia reperfusion contributes to adverse clinical outcomes following kidney transplantation
Published in Kidney international (01-05-2019)“…Renal ischemia reperfusion injury (IRI) adversely affects clinical outcomes following kidney transplantation. Understanding the cellular mechanisms and the…”
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Bone marrow-derived cells and their conditioned medium induce microvascular repair in uremic rats by stimulation of endogenous repair mechanisms
Published in Scientific reports (25-08-2017)“…The reduced number of circulating stem/progenitor cells that is found in chronic kidney disease (CKD) patients may contribute to impaired angiogenic repair and…”
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10
Soluble Flt-1 links microvascular disease with heart failure in CKD
Published in Basic research in cardiology (01-05-2015)“…Chronic kidney disease (CKD) is associated with an increased risk of heart failure (HF). Elevated plasma concentrations of soluble Flt-1 (sFlt-1) have been…”
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11
Angiogenesis and diabetes: different responses to pro-angiogenic factors in the chorioallantoic membrane assay
Published in Molecular medicine (Cambridge, Mass.) (01-11-2008)“…Hyperglycemia induces defects in angiogenesis without alteration in the expression of major vascular growth factors in the chicken chorioallantoic membrane…”
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Orally Administered Rapamycin Does Not Modify Rat Aortic Vascular Tone
Published in Journal of cardiovascular pharmacology (01-02-2007)“…Rapamycin (RP; rapamune, sirolimus) is a potent inhibitor of vascular smooth muscle cell proliferation and migration. RP was demonstrated to reduce vascular…”
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13
SP259EFFECTS OF BONE MARROW-DERIVED CELLS AND THE MANIPULATION OF THE SDF-1/CXCR4 AXIS IN CKD-ASSOCIATED HEART REMODELING
Published in Nephrology, dialysis, transplantation (01-05-2016)Get full text
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14
Purification and characterization of a neutral endopeptidase-like enzyme from human urine
Published in Journal of hypertension (01-12-1998)“…OBJECTIVEThe aims of this study were to purify and characterize a neutral endopeptidase-like enzyme (NEP- like) in human urine and propose a rapid, sensitive…”
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Off-target effects and adverse outcomes of fibroblast growth factor 23 in chronic kidney disease
Published in Portuguese journal of nephrology & hypertension (01-03-2018)“…Chronic kidney disease (CKD) patients have a high risk of death, especially cardiovascular death. High fibroblast growth factor 23 (FGF23) levels are…”
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