Search Results - "Di Giorgi, Nicoletta"
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GEN-RWD Sandbox: bridging the gap between hospital data privacy and external research insights with distributed analytics
Published in BMC medical informatics and decision making (17-06-2024)“…Artificial intelligence (AI) has become a pivotal tool in advancing contemporary personalised medicine, with the goal of tailoring treatments to individual…”
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2
Lipid biomarkers in statin users with coronary artery disease annotated by coronary computed tomography angiography
Published in Scientific reports (18-06-2021)“…Molecular markers are suggested to improve the diagnostic and prognostic accuracy in patients with coronary artery disease (CAD) beyond current clinical scores…”
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3
Proteomic Modulation in TGF-β-Treated Cholangiocytes Induced by Curcumin Nanoparticles
Published in International journal of molecular sciences (22-06-2023)“…Curcumin is a natural polyphenol that exhibits a variety of beneficial effects on health, including anti-inflammatory, antioxidant, and hepato-protective…”
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4
Real-world evidence evaluation of LDL-C in hospitalized patients: a population-based observational study in the timeframe 2021-2022
Published in Lipids in health and disease (24-07-2024)“…European registries and retrospective cohort studies have highlighted the failure to achieve low-density lipoprotein-cholesterol (LDL-C) targets in many very…”
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Molecular Characterization of Plasma HDL, LDL, and VLDL Lipids Cargos from Atherosclerotic Patients with Advanced Carotid Lesions: A Preliminary Report
Published in International journal of molecular sciences (18-10-2022)“…Carotid atherosclerosis represents a relevant healthcare problem, since unstable plaques are responsible for approximately 15% of neurologic events, namely…”
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6
Proteomics and lipidomic analysis reveal dysregulated pathways associated with loss of sacsin
Published in Frontiers in neuroscience (07-06-2024)“…Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a rare incurable neurodegenerative disease caused by mutations in the gene, which codes…”
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Biological Effects of Transforming Growth Factor Beta in Human Cholangiocytes
Published in Biology (Basel, Switzerland) (08-04-2022)“…TGF-β is a cytokine implicated in multiple cellular responses, including cell cycle regulation, fibrogenesis, angiogenesis and immune modulation. In response…”
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Salivary Proteomics Markers for Preclinical Sjögren’s Syndrome: A Pilot Study
Published in Biomolecules (Basel, Switzerland) (24-05-2022)“…Primary Sjögren’s syndrome (pSS) is a complex autoimmune disorder that particularly affects the salivary and lachrymal glands, generally causing a typical…”
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Blood M2-like Monocyte Polarization Is Associated with Calcific Plaque Phenotype in Stable Coronary Artery Disease: A Sub-Study of SMARTool Clinical Trial
Published in Biomedicines (28-02-2022)“…Atherosclerosis is a chronic inflammatory disease. The balance between pro- and anti-inflammatory factors, acting on the arterial wall, promotes less or more…”
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10
Predictive Added Value of Selected Plasma Lipids to a Re-estimated Minimal Risk Tool
Published in Frontiers in cardiovascular medicine (16-07-2021)“…Background: Lipidomics is emerging for biomarker discovery in cardiovascular disease, and circulating lipids are increasingly incorporated in risk models to…”
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11
1068-P: Reassessing Insulin Therapy In Diabetes of the Exocrine Pancreas-A Pilot Study
Published in Diabetes (New York, N.Y.) (01-06-2024)“…Cohort studies have demonstrated that subjects with diabetes of the exocrine pancreas (DEP) are mostly treated with basal bolus insulin. To reassess insulin…”
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Epidemiological and clinicopathological features of patients (pts) with early- (EOPC) and late-onset pancreatic cancer (LOPC): A mono-institutional retrospective analysis
Published in Journal of clinical oncology (01-06-2023)“…10533 Background: PC is mostly diagnosed in the 7th decade of life. Recent evidence suggests a rising incidence of both EOPC and LOPC. However, there are few…”
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13
Transcriptional level evaluation of osteopontin/miRNA-181a axis in hepatocellular carcinoma cell line-secreted extracellular vesicles
Published in Pathology, research and practice (01-10-2022)“…Recent evidence suggested the role of secreted extracellular vesicles (EVs) in the intracellular signalling within the liver becoming a promising candidate as…”
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A specific plasma lipid signature associated with high triglycerides and low HDL cholesterol identifies residual CAD risk in patients with chronic coronary syndrome
Published in Atherosclerosis (01-12-2021)“…Elevated triglycerides (TG) and low high-density lipoprotein cholesterol (HDL-C) define a specific lipid profile associated with residual coronary artery…”
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Italian real world artificial intelligence (AI) based analysis of early-onset colorectal cancer: The ERCOLE study
Published in Journal of clinical oncology (01-06-2023)“…e15539 Background: Early-onset colorectal cancer (EOCRC), defined as CRC diagnosed among individuals younger than 50 yrs, is becoming a public health issue,…”
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Association of MMP9 with adverse features of plaque progression and residual inflammatory risk in patients with chronic coronary syndrome (CCS)
Published in Vascular pharmacology (01-10-2022)“…BACKGROUND AND AIMSMMP-9 is a predictor of atherosclerotic plaque instability and adverse cardiovascular events, but longitudinal data on the association…”
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Plasma lipidomics and coronary plaque changes: a substudy of the SMARTool clinical trial
Published in European heart journal cardiovascular imaging (31-07-2024)“…Abstract Aims To date, no studies have investigated the association between lipid species and coronary plaque changes over time, quantitatively assessed by…”
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