Search Results - "Di Giambattista, M"

Inhibitors in German hemophilia A patients treated with a double virus inactivated factor VIII concentrate bind to the C2 domain of FVIII light chain by Laub, R, Di Giambattista, M, Fondu, P, Brackmann, H H, Lenk, H, Saenko, E L, Felch, M, Scandella, D

“…To reduce the risk of transmission of hepatitis A virus, an Octapharma produced factor VIII (fVIII) concentrate treated with solvent detergent (FVIII-SD) was…”
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Modification of factor VIII in therapeutic concentrates after virus inactivation by solvent-detergent and pasteurisation by Raut, S, Di Giambattista, M, Bevan, S A, Hubbard, A R, Barrowcliffe, T W, Laub, R

“…The addition of a pasteurisation step to a solvent/detergent (SD) treated FVIII concentrate has recently resulted in enhanced inhibitor incidence in patients…”
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Inhibition of protein synthesis by streptogramins and related antibiotics by Cocito, C, Di Giambattista, M, Nyssen, E, Vannuffel, P

“…The streptogramins and related antibiotics (the lincosamides and macrolides) (MLS) are important inhibitors of bacterial protein synthesis. The key reaction in…”
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Prevalence of human erythrovirus B19 DNA in healthy Belgian blood donors and correlation with specific antibodies against structural and non-structural viral proteins by Thomas, I., Di Giambattista, M., Gérard, C., Mathys, E., Hougardy, V., Latour, B., Branckaert, T., Laub, R.

“…Background and Objectives Human parvovirus (erythrovirus) B19 is recognized as a major contaminant of blood and blood products. To reduce the risk of…”
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Factor VIII inhibitors in previously treated haemophilia A patients with a double virus-inactivated plasma derived factor VIII concentrate by Peerlinck, K, Arnout, J, Di Giambattista, M, Gilles, J G, Laub, R, Jacquemin, M, Saint-Remy, J M, Vermylen, J

“…Antibodies to factor VIII (inhibitors) are usually produced at the beginning of treatment with factor VIII and are rare in multitransfused patients. Such…”
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The molecular basis of the inhibitory activities of type A and type B synergimycins and related antibiotics on ribosomes by Di Giambattista, M, Chinali, G, Cocito, C

“…Synergimycins A and B act synergistically in vivo; the mixture of the two compounds is more powerful than the individual components and their combined action…”
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Hypoxia enables B19 erythrovirus to yield abundant infectious progeny in a pluripotent erythroid cell line by Caillet-Fauquet, P., Draps, M-L., Giambattista, M. Di, Launoit, Y de, Laub, Ruth

“…B19 may cause mild to severe clinical manifestations. Owing to the remarkable tropism of B19 for red blood cell progenitors, there is a lack of satisfactory…”
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Heating Lyophilised Factor VIII Does Not Alter Its Recognition by Specific Antibodies by Gilles, J. G., di Giambattista, M., Laub, R., Saint-Remy, J. M. R.

“…Background and objectives: Alterations of factor VIII (FVIII) during preparation procedures can potentially affect its immunogenicity. One method evaluating…”
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Analysis of fluorescence quenching of ribosome-bound virginiamycin S by Di Giambattista, M, Ide, G, Engelborghs, Y, Cocito, C

“…The two virginiamycin components VM and VS interact synergistically with bacterial ribosomes in vitro and in vivo. Ribosome affinity for virginiamycin S…”
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Fluorescence stopped flow analysis of the interaction of virginiamycin components and erythromycin with bacterial ribosomes by Moureau, P, Engelborghs, Y, Di Giambattista, M, Cocito, C

“…The kinetics of the interaction between the 50 S subunits (R) of bacterial ribosomes and the antibiotics virginiamycin S (VS), virginiamycin M (VM), and…”
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Polychlorinated biphenyls and organochlorine pesticides are eliminated from therapeutic Factor VIII and immunoglobulin concentrates and reduced in albumin by plasma fractionation by Covaci, A., Laub, R., Di Giambattista, M., Branckaert, T., Hougardy, V., Schepens, P.

“…Background and Objectives Persistent organochlorine pollutants, such as polychlorinated biphenyls (PCBs) and organochlorine pesticides, are found in the…”
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Ribosome protection by tRNA derivatives against inactivation by virginiamycin M: evidence for two types of interaction of tRNA with the donor site of peptidyl transferase by Chinali, G, Di Giambattista, M, Cocito, C

“…Virginiamycin M (VM) was previously shown to interfere with the function of both the A and P sites of ribosomes and to inactivate tRNA-free ribosomes but not…”
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Identification of a single base change in ribosomal RNA leading to erythromycin resistance by VANNUFFEL, P, DI GIAMBATTISTA, M, MORGAN, E. A, COCITO, C

“…The molecular basis of a mutation conferring an erythromycin-resistance phenotype was explored, as an approach to the role of 23 S rRNA in the…”
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Antagonistic interactions of macrolides and synergimycins on bacterial ribosomes by Di Giambattista, M, Vannuffel, P, Sunazuka, T, Jacob, T, Omura, S, Cocito, C

“…The affinity of ribosomes for VS (virginiamycin S, a type B synergimycin) is known to be increased by VM (virginiamycin M, a type A synergimycin)…”
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Kinetics of binding of macrolides, lincosamides, and synergimycins to ribosomes by Di Giambattista, M, Engelborghs, Y, Nyssen, E, Cocito, C

“…The synergistic effect of type A (virginiamycin M (VM)) and type B (virginiamycin S (VS)) synergimycins and their antagonistic effect against erythromycin (a…”
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Heating Lyophilised Factor VIII Does Not Alter Its Recognition by Specific Antibodies by Gilles, J. G., di Giambattista, M., Laub, R., Saint-Remy, J. M. R.

“…Background and objectives: Alterations of factor Vili (FVIII) during preparation procedures can potentially affect its immunogenicity. One method evaluating…”
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The role of rRNA bases in the interaction of peptidyltransferase inhibitors with bacterial ribosomes by VANNUFFEL, P, DI GIAMBATTISTA, M, COCITO, C

“…Synergism of streptogramins A (virginiamycin M, VM) and B (virginiamycin S, VS), peptidyltransferase inhibitors, was explored in EM4/pLC7-21 (wild type) and…”
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Analysis of physiological functions of different human serum albumin pharmaceutical preparations by Di Giambattista, M, Mascio, L, Branckaert, T, Laub, R

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Action of ions and pH on the binding of virginiamycin S to ribosomes by Di Giambattista, M, Cocito, C

“…Virginiamycin S (VS) binds to the 50 S ribosomal subunits (KaVS = 2.5 X 10(6) M-1); the affinity of ribosomes for VS undergoes a 6-fold increase (KaVS = 15 X…”
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Affinity labeling of the virginiamycin S binding site on the bacterial ribosome by Di Giambattista, M, Nyssen, E, Pecher, A, Cocito, C

“…Virginiamycin S (VS, a type B synergimycin) inhibits peptide bond synthesis in vitro and in vivo. The attachment of virginiamycin S to the large ribosomal…”
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