Search Results - "Di Filippo, Marzia"

GPRuler: Metabolic gene-protein-reaction rules automatic reconstruction by Di Filippo, Marzia, Damiani, Chiara, Pescini, Dario

“…Metabolic network models are increasingly being used in health care and industry. As a consequence, many tools have been released to automate their…”
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INTEGRATE: Model-based multi-omics data integration to characterize multi-level metabolic regulation by Di Filippo, Marzia, Pescini, Dario, Galuzzi, Bruno Giovanni, Bonanomi, Marcella, Gaglio, Daniela, Mangano, Eleonora, Consolandi, Clarissa, Alberghina, Lilia, Vanoni, Marco, Damiani, Chiara

“…Metabolism is directly and indirectly fine-tuned by a complex web of interacting regulatory mechanisms that fall into two major classes. On the one hand, the…”
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Single-cell Digital Twins for Cancer Preclinical Investigation by Filippo, Marzia Di, Damiani, Chiara, Vanoni, Marco, Maspero, Davide, Mauri, Giancarlo, Alberghina, Lilia, Pescini, Dario

“…Laboratory models derived from clinical samples represent a solid platform in preclinical research for drug testing and investigation of disease mechanisms…”
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Integration of single-cell RNA-seq data into population models to characterize cancer metabolism by Damiani, Chiara, Maspero, Davide, Di Filippo, Marzia, Colombo, Riccardo, Pescini, Dario, Graudenzi, Alex, Westerhoff, Hans Victor, Alberghina, Lilia, Vanoni, Marco, Mauri, Giancarlo

“…Metabolic reprogramming is a general feature of cancer cells. Regrettably, the comprehensive quantification of metabolites in biological specimens does not…”
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A Mobile App Leveraging Citizenship Engagement to Perform Anonymized Longitudinal Studies in the Context of COVID-19 Adverse Drug Reaction Monitoring: Development and Usability Study by Di Filippo, Marzia, Avellone, Alessandro, Belingheri, Michael, Paladino, Maria Emilia, Riva, Michele Augusto, Zambon, Antonella, Pescini, Dario

“…Background: Over the past few years, studies have increasingly focused on the development of mobile apps as complementary tools to existing traditional…”
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MaREA4Galaxy: Metabolic reaction enrichment analysis and visualization of RNA-seq data within Galaxy by Damiani, Chiara, Rovida, Lorenzo, Maspero, Davide, Sala, Irene, Rosato, Luca, Di Filippo, Marzia, Pescini, Dario, Graudenzi, Alex, Antoniotti, Marco, Mauri, Giancarlo

“…[Display omitted] We present MaREA4Galaxy, a user-friendly tool that allows a user to characterize and to graphically compare groups of samples with different…”
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GPRuler: Metabolic gene-protein-reaction rules automatic reconstruction by Marzia Di Filippo, Chiara Damiani, Dario Pescini

“…Metabolic network models are increasingly being used in health care and industry. As a consequence, many tools have been released to automate their…”
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popFBA: tackling intratumour heterogeneity with Flux Balance Analysis by Damiani, Chiara, Di Filippo, Marzia, Pescini, Dario, Maspero, Davide, Colombo, Riccardo, Mauri, Giancarlo

“…Intratumour heterogeneity poses many challenges to the treatment of cancer. Unfortunately, the transcriptional and metabolic information retrieved by currently…”
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Integration of transcriptomic data and metabolic networks in cancer samples reveals highly significant prognostic power by Graudenzi, Alex, Maspero, Davide, Di Filippo, Marzia, Gnugnoli, Marco, Isella, Claudio, Mauri, Giancarlo, Medico, Enzo, Antoniotti, Marco, Damiani, Chiara

“…[Display omitted] •Projecting RNA-seq data onto metabolic nets allows to study deregulated metabolism.•Data integration enables to cluster samples into cancer…”
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Zooming-in on cancer metabolic rewiring with tissue specific constraint-based models by Di Filippo, Marzia, Colombo, Riccardo, Damiani, Chiara, Pescini, Dario, Gaglio, Daniela, Vanoni, Marco, Alberghina, Lilia, Mauri, Giancarlo

“…[Display omitted] •Genome-scale metabolic models are comprehensives but difficult to control and to analyze.•We manually reconstructed core models that zoom-in…”
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Metabolic enrichment through functional gene rules by Maspero, Davide, Isella, Claudio, Di Filippo, Marzia, Graudenzi, Alex, Bellomo, Sara Erika, Antoniotti, Marco, Mauri, Giancarlo, Medico, Enzo, Damiani, Chiara

“…It is well known that tumors originating from the same tissue have different prognosis and sensitivity to treatments. Over the last decade, cancer genomics…”
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