Search Results - "Di Fazio, Pietro"

The Crosstalk of miRNA and Oxidative Stress in the Liver: From Physiology to Pathology and Clinical Implications by Klieser, Eckhard, Mayr, Christian, Kiesslich, Tobias, Wissniowski, Till, Fazio, Pietro Di, Neureiter, Daniel, Ocker, Matthias

“…The liver is the central metabolic organ of mammals. In humans, most diseases of the liver are primarily caused by an unhealthy lifestyle-high fat diet, drug…”
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Morphological Alterations in Gastrocnemius and Soleus Muscles in Male and Female Mice in a Fibromyalgia Model by Bonaterra, Gabriel Alejandro, Then, Hanna, Oezel, Lisa, Schwarzbach, Hans, Ocker, Matthias, Thieme, Kati, Di Fazio, Pietro, Kinscherf, Ralf

“…Fibromyalgia (FM) is a chronic musculoskeletal pain disorder, characterized by chronic widespread pain and bodily tenderness and is often accompanied by…”
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Comprehensive immunohistochemical analysis of histone deacetylases in pancreatic neuroendocrine tumors: HDAC5 as a predictor of poor clinical outcome by Klieser, Eckhard, MD, Urbas, Romana, MD PhD, Stättner, Stefan, MD, Primavesi, Florian, MD, Jäger, Tarkan, MD, Dinnewitzer, Adam, MD, Mayr, Christian, PhD, Kiesslich, Tobias, PhD, Holzmann, Klaus, MSc PhD, Di Fazio, Pietro, PhD, Neureiter, Daniel, MD,MA, Swierczynski, Stefan, MSc

“…Epigenetic factors contribute to carcinogenesis, tumor promotion and chemoresistance. Histone deacetylases (HDACs) are epigenetic regulators that primarily…”
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HDAC-Linked "Proliferative" miRNA Expression Pattern in Pancreatic Neuroendocrine Tumors by Klieser, Eckhard, Urbas, Romana, Swierczynski, Stefan, Stättner, Stefan, Primavesi, Florian, Jäger, Tarkan, Mayr, Christian, Kiesslich, Tobias, Fazio, Pietro Di, Helm, Katharina, Neureiter, Daniel

“…Epigenetic factors are essentially involved in carcinogenesis, tumor promotion, and chemoresistance. Two epigenetic key players are miRNAs and histone…”
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Expression of hsa-let-7b-5p, hsa-let-7f-5p, and hsa-miR-222-3p and their putative targets HMGA2 and CDKN1B in typical and atypical carcinoid tumors of the lung by Di Fazio, Pietro, Maass, Moritz, Roth, Silvia, Meyer, Christian, Grups, Joana, Rexin, Peter, Bartsch, Detlef K, Kirschbaum, Andreas

“…Typical and atypical carcinoid tumors belong to the neuroendocrine lung tumors. They have low recurrence and proliferation rate, lymph node, and distant…”
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Influence of five potential anticancer drugs on wnt pathway and cell survival in human biliary tract cancer cells by Wachter, Julia, Neureiter, Daniel, Alinger, Beate, Pichler, Martin, Fuereder, Julia, Oberdanner, Christian, Di Fazio, Pietro, Ocker, Matthias, Berr, Frieder, Kiesslich, Tobias

“…The role of Wnt signalling in carcinogenesis suggests compounds targeting this pathway as potential anti-cancer drugs. Several studies report activation of Wnt…”
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Targeting menin: a promising therapeutic strategy for susceptible acute leukemia subtypes by Di Fazio, Pietro

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The epitranscriptome: At the crossroad of cancer prognosis by Di Fazio, Pietro

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Exploring the MEN1 dependent modulation of caspase 8 and caspase 3 in human pancreatic and murine embryo fibroblast cells by Wagener, Nele, Buchholz, Malte, Bertolino, Philippe, Zhang, Chang X., Di Fazio, Pietro

“…MEN1 mutation causes pancreatic neuroendocrine neoplasia and benign malignancies of the parathyroid, the adrenal cortex and pituitary gland. The…”
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The Expression of Autophagy-Associated Genes Represents a Valid Footprint for Aggressive Pancreatic Neuroendocrine Neoplasms by Matrood, Sami, Melms, Leander Edwin, Bartsch, Detlef Klaus, Di Fazio, Pietro

“…Pancreatic neuroendocrine neoplasms (pNEN) are rare and heterogeneous tumors. Previous investigations have shown that autophagy can be a target for cancer…”
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Dual anticancer activity in a single compound: visible-light-induced apoptosis by an antiangiogenic iridium complex by Kastl, Anja, Wilbuer, Alexander, Merkel, Anna Lena, Feng, Li, Di Fazio, Pietro, Ocker, Matthias, Meggers, Eric

“…A metal complex is identified in which the metal fulfills two independent functions: as a structural scaffold for the specific molecular recognition of protein…”
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Gastric enterochromaffin‐like cell changes in multiple endocrine neoplasia type 1 by Manoharan, Jerena, Anlauf, Martin, Albers, Max B., Denzer, Ulrike W., Mintziras, Ioannis, Wächter, Sabine, Di Fazio, Pietro, Bollmann, Carmen, Bartsch, Detlef K.

“…Background Gastric enterochromaffin‐like cell (ECL) tumours can occur in patients with multiple endocrine neoplasia type 1 (MEN1), especially in those affected…”
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Additive antitumour response to the rabbit VX2 hepatoma by combined radio frequency ablation and toll like receptor 9 stimulation by Behm, Barbara, Di Fazio, Pietro, Michl, Patrick, Neureiter, Daniel, Kemmerling, Ralf, Hahn, Eckhart Georg, Strobel, Deike, Gress, Thomas, Schuppan, Detlef, Wissniowski, Thaddaeus Till

“…Radiofrequency ablation (RFA), a palliative therapeutic option for solid hepatic tumours, stimulates localised and systemic antitumour cytotoxic T cells. We…”
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Mesenteric fibrosis in patients with small intestinal neuroendocrine tumors is associated with enrichment of alpha‐smooth muscle actin‐positive fibrosis and COMP‐expressing stromal cells by Graf, Sebastian D., Keber, Corinna U., Hattesohl, Akira, Teply‐Szymanski, Julia, Hattesohl, Sophia, Guder, Marc, Gercke, Norman, Di Fazio, Pietro, Slater, Emily P., Jesinghaus, Moritz, Denkert, Carsten, Bartsch, Detlef K., Lehman, Bettina

“…Neuroendocrine tumors of the small intestine (SI‐NETs) often develop lymph node metastasis (LNM)‐induced mesenteric fibrosis (MF). MF can cause intestinal…”
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Pharmacological Inhibition of Class IIA HDACs by LMK-235 in Pancreatic Neuroendocrine Tumor Cells by Wanek, Julia, Gaisberger, Martin, Beyreis, Marlena, Mayr, Christian, Helm, Katharina, Primavesi, Florian, Jäger, Tarkan, Di Fazio, Pietro, Jakab, Martin, Wagner, Andrej, Neureiter, Daniel, Kiesslich, Tobias

“…Histone deacetylases (HDACs) play a key role in epigenetic mechanisms in health and disease and their dysfunction is implied in several cancer entities…”
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The Role of TGF-β1 and Mutant SMAD4 on Epithelial-Mesenchymal Transition Features in Head and Neck Squamous Cell Carcinoma Cell Lines by Bette, Michael, Reinhardt, Laura, Gansukh, Uyanga, Xiang-Tischhauser, Li, Meskeh, Haifa, Di Fazio, Pietro, Buchholz, Malte, Stuck, Boris A, Mandic, Robert

“…The aim of the present study was to investigate possible differences in the sensitivity of HNSCC cells to known EMT regulators. Three HNSCC cell lines…”
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Frequency and Prognostic Significance of Intertumoural Heterogeneity in Multifocal Jejunoileal Neuroendocrine Tumours by Jesinghaus, Moritz, Poppinga, Jelte, Lehman, Bettina, Maurer, Elisabeth, Ramaswamy, Annette, Grass, Albert, Di Fazio, Pietro, Rinke, Anja, Denkert, Carsten, Bartsch, Detlef K

“…Background: A recent study found that multifocal jejunoileal neuroendocrine tumors (SI-NETs) are genetically unrelated synchronous neoplasms. So far, it is…”
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Whole-exome sequencing of calcitonin-producing pancreatic neuroendocrine neoplasms indicates a unique molecular signature by Döring, Claudia, Peer, Katharina, Bankov, Katrin, Bollmann, Carmen, Ramaswamy, Annette, Di Fazio, Pietro, Wild, Peter Johannes, Bartsch, Detlef Klaus

“…Introduction Calcitonin-producing pancreatic neuroendocrine neoplasms (CT-pNENs) are an extremely rare clinical entity, with approximately 60 cases reported…”
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Prostate-Specific Membrane Antigen in Anaplastic and Poorly Differentiated Thyroid Cancer—A New Diagnostic and Therapeutic Target? by Wächter, Sabine, Di Fazio, Pietro, Maurer, Elisabeth, Manoharan, Jerena, Keber, Corinna, Pfestroff, Andreas, Librizzi, Damiano, Bartsch, Detlef K., Luster, Markus, Eilsberger, Friederike

“…Several studies have demonstrated an expression of the prostate-specific membrane antigen (PSMA) in the cancer-related neovasculature of thyroid malignancies…”
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Downregulation of HMGA2 by the pan-deacetylase inhibitor panobinostat is dependent on hsa-let-7b expression in liver cancer cell lines by Di Fazio, Pietro, Montalbano, Roberta, Neureiter, Daniel, Alinger, Beate, Schmidt, Ansgar, Merkel, Anna Lena, Quint, Karl, Ocker, Matthias

“…Inhibitors of protein deacetylases represent a novel therapeutic option for cancer diseases due to their effects on transcriptional regulation by interfering…”
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