Search Results - "Di Dario, Marco"

Dysregulated copper transport in multiple sclerosis may cause demyelination via astrocytes by Colombo, Emanuela, Triolo, Daniela, Bassani, Claudia, Bedogni, Francesco, Di Dario, Marco, Dina, Giorgia, Fredrickx, Evelien, Fermo, Isabella, Martinelli, Vittorio, Newcombe, Jia, Taveggia, Carla, Quattrini, Angelo, Comi, Giancarlo, Farina, Cinthia

“…Demyelination is a key pathogenic feature ofmultiple sclerosis (MS). Here, we evaluated the astrocyte contribution to myelin loss and focused on the…”
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Fingolimod may support neuroprotection via blockade of astrocyte nitric oxide by Colombo, Emanuela, Di Dario, Marco, Capitolo, Eleonora, Chaabane, Linda, Newcombe, Jia, Martino, Gianvito, Farina, Cinthia

“…Objective Although astrocytes participate in glial scar formation and tissue repair, dysregulation of the NFκB pathway and of nitric oxide (NO) production in…”
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Inferring Multiple Sclerosis Stages from the Blood Transcriptome via Machine Learning by Acquaviva, Massimo, Menon, Ramesh, Di Dario, Marco, Dalla Costa, Gloria, Romeo, Marzia, Sangalli, Francesca, Colombo, Bruno, Moiola, Lucia, Martinelli, Vittorio, Comi, Giancarlo, Farina, Cinthia

“…Peripheral blood mononuclear cells (PBMCs) bear specific dysregulations in genes and pathways at distinct stages of multiple sclerosis (MS) that may help with…”
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Gender-based blood transcriptomes and interactomes in multiple sclerosis: Involvement of SP1 dependent gene transcription by Menon, Ramesh, Di Dario, Marco, Cordiglieri, Chiara, Musio, Silvia, La Mantia, Loredana, Milanese, Clara, Di Stefano, Anna Luisa, Crabbio, Massimo, Franciotta, Diego, Bergamaschi, Roberto, Pedotti, Rosetta, Medico, Enzo, Farina, Cinthia

“…Abstract In this study we investigated the contribution of gender to global gene expression in peripheral blood mononuclear cells from multiple sclerosis (MS)…”
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Dysregulation of MS risk genes and pathways at distinct stages of disease by Srinivasan, Sundararajan, Di Dario, Marco, Russo, Alessandra, Menon, Ramesh, Brini, Elena, Romeo, Marzia, Sangalli, Francesca, Costa, Gloria Dalla, Rodegher, Mariaemma, Radaelli, Marta, Moiola, Lucia, Cantarella, Daniela, Medico, Enzo, Martino, Gianvito, Furlan, Roberto, Martinelli, Vittorio, Comi, Giancarlo, Farina, Cinthia

“…To perform systematic transcriptomic analysis of multiple sclerosis (MS) risk genes in peripheral blood mononuclear cells (PBMCs) of subjects with distinct MS…”
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Critical role for prokineticin 2 in CNS autoimmunity by Abou-Hamdan, Mhamad, Costanza, Massimo, Fontana, Elena, Di Dario, Marco, Musio, Silvia, Congiu, Cenzo, Onnis, Valentina, Lattanzi, Roberta, Radaelli, Marta, Martinelli, Vittorio, Salvadori, Severo, Negri, Lucia, Poliani, Pietro Luigi, Farina, Cinthia, Balboni, Gianfranco, Steinman, Lawrence, Pedotti, Rosetta

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HNF4α, SP1 and c-myc are master regulators of CNS autoimmunity by Colombo, Emanuela, Di Dario, Marco, Menon, Ramesh, Valente, Maria Maddalena, Bassani, Claudia, Sarno, Nicole, Mazza, Davide, Montini, Federico, Moiola, Lucia, Comi, Giancarlo, Martinelli, Vittorio, Farina, Cinthia

“…Hepatocyte nuclear factor 4 α (HNF4α), a transcription factor (TF) essential for embryonic development, has been recently shown to regulate the expression of…”
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Gene expression analysis of histamine receptors in peripheral blood mononuclear cells from individuals with clinically-isolated syndrome and different stages of multiple sclerosis by Costanza, Massimo, Di Dario, Marco, Steinman, Lawrence, Farina, Cinthia, Pedotti, Rosetta

“…Abstract Along with their established role in allergic reactions, histamine and its receptors have been implicated in the pathology of multiple sclerosis (MS)…”
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A cell type-specific transcriptomic approach to map B cell and monocyte type I interferon-linked pathogenic signatures in Multiple Sclerosis by Severa, Martina, Rizzo, Fabiana, Srinivasan, Sundararajan, Di Dario, Marco, Giacomini, Elena, Buscarinu, Maria Chiara, Cruciani, Melania, Etna, Marilena P., Sandini, Silvia, Mechelli, Rosella, Farina, Antonella, Trivedi, Pankaj, Hertzog, Paul J., Salvetti, Marco, Farina, Cinthia, Coccia, Eliana M.

“…Alteration in endogenous Interferon (IFN) system may profoundly impact immune cell function in autoimmune diseases. Here, we provide evidence that…”
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Gene expression analysis of histamine receptors in peripheral blood mononuclear cells from clinically-isolated syndrome and multiple sclerosis patients by Costanza, Massimo, Di Dario, Marco, Steinman, Lawrence, Farina, Cinthia, Pedotti, Rosetta

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Peripheral transcriptional control in multiple sclerosis: Hepatocyte nuclear factor 4 alpha regulates immune cell activation and autoimmunity by Di Dario, Marco, Menon, Ramesh, Colombo, Emanuela, Radaelli, Marta, Martinelli, Vittorio, Comi, Giancarlo, Farina, Cinthia

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Fingolimod may support neuroprotection via blockade of astrocyte S1P and cytokine signaling cascades in Multiple Sclerosis by Colombo, Emanuela, Di Dario, Marco, Capitolo, Eleonora, Chaabane, Linda, Newcombe, Jia, Martino, Gianvito, Farina, Cinthia

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Myeloid cells as target of fingolimod action in multiple sclerosis by Di Dario, Marco, Colombo, Emanuela, Govi, Chiara, De Feo, Donatella, Messina, Maria José, Romeo, Marzia, Sangalli, Francesca, Moiola, Lucia, Rodegher, Mariaemma, Martino, Gianvito, Martinelli, Vittorio, Comi, Giancarlo, Farina, Cinthia

“…OBJECTIVE:To track the effects of fingolimod, an approved drug for multiple sclerosis (MS), on the activation of myeloid cells from the periphery to the CNS…”
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Critical role for prokineticin 2 in CNS autoimmunity by Abou-Hamdan, Mhamad, Costanza, Massimo, Fontana, Elena, Di Dario, Marco, Musio, Silvia, Congiu, Cenzo, Onnis, Valentina, Lattanzi, Roberta, Radaelli, Marta, Martinelli, Vittorio, Salvadori, Severo, Negri, Lucia, Poliani, Pietro Luigi, Farina, Cinthia, Balboni, Gianfranco, Steinman, Lawrence, Pedotti, Rosetta

“…OBJECTIVE:To investigate the potential role of prokineticin 2 (PK2), a bioactive peptide involved in multiple biological functions including immune modulation,…”
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An important role for prokineticin 2 in autoimmune CNS demyelination by Abou-hamdan, Mhamad, Costanza, Massimo, Fontana, Elena, Musio, Silvia, Di Dario, Marco, Congiu, Cenzo, Onnis, Valentina, Lattanzi, Roberta, Negri, Lucia, Poliani, Pietro Luigi, Farina, Cinthia, Balboni, Gianfranco, Steinman, Lawrence, Pedotti, Rosetta

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Gender-based blood transcriptomes and interactomes in multiple sclerosis: Involvement of SP1 dependent gene transcription: Gender, Sex Hormones, Pregnancy and Autoimmunity by MENON, Ramesh, DI DARIO, Marco, PEDOTTI, Rosetta, MEDICO, Enzo, FARINA, Cinthia, CORDIGLIERI, Chiara, MUSIO, Silvia, LA MANTIA, Loredana, MILANESE, Clara, DI STEFANO, Anna Luisa, CRABBIO, Massimo, FRANCIOTTA, Diego, BERGAMASCHI, Roberto

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