Search Results - "Di Certo, Maria Grazia"

Neuroimmune Dysregulation in Prepubertal and Adolescent Individuals Affected by Klinefelter Syndrome by Tarani, Luigi, Ceci, Flavio Maria, Carito, Valentina, Ferraguti, Giampiero, Petrella, Carla, Greco, Antonio, Ralli, Massimo, Minni, Antonio, Spaziani, Matteo, Isidori, Andrea M, Certo, Maria Grazia Di, Barbato, Christian, Putotto, Carolina, Fiore, Marco

“…The syndrome Klinefelter syndrome (KS) is a genetic disorder due to an extra X chromosome in males. Many cases remain undiagnosed until the onset of major…”
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SMN protein promotes membrane compartmentalization of ribosomal protein S6 transcript in human fibroblasts by Gabanella, Francesca, Onori, Annalisa, Ralli, Massimo, Greco, Antonio, Passananti, Claudio, Di Certo, Maria Grazia

“…Alterations of RNA homeostasis can lead to severe pathological conditions. The Survival of Motor Neuron (SMN) protein, which is reduced in Spinal Muscular…”
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Exploring Mitochondrial Localization of SARS-CoV-2 RNA by Padlock Assay: A Pilot Study in Human Placenta by Gabanella, Francesca, Barbato, Christian, Corbi, Nicoletta, Fiore, Marco, Petrella, Carla, de Vincentiis, Marco, Greco, Antonio, Ferraguti, Giampiero, Corsi, Alessandro, Ralli, Massimo, Pecorella, Irene, Di Gioia, Cira, Pecorini, Francesco, Brunelli, Roberto, Passananti, Claudio, Minni, Antonio, Di Certo, Maria Grazia

“…The ongoing COVID-19 pandemic dictated new priorities in biomedicine research. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative…”
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Alzheimer's Disease: New Concepts on the Role of Autoimmunity and NLRP3 Inflammasome in the Pathogenesis of the Disease by Severini, Cinzia, Barbato, Christian, Di Certo, Maria Grazia, Gabanella, Francesca, Petrella, Carla, Di Stadio, Arianna, de Vincentiis, Marco, Polimeni, Antonella, Ralli, Massimo, Greco, Antonio

“…Alzheimer’s disease (AD), recognized as the most common neurodegenerative disorder, is clinically characterized by the presence of extracellular beta-amyloid…”
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Characteristic Hallmarks of Aging and the Impact on Carcinogenesis by Terracina, Sergio, Ferraguti, Giampiero, Petrella, Carla, Bruno, Sabina Maria, Blaconà, Giovanna, Di Certo, Maria Grazia, Minni, Antonio, Greco, Antonio, Musacchio, Angela, Ralli, Massimo, Tarani, Luigi, Ceccanti, Mauro, Polimeni, Antonella, Triaca, Viviana, Fiore, Marco

“…Evidence shows that there is a synergistic, bidirectional association between cancer and aging with many shared traits. Age itself is a risk factor for the…”
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SMN Deficiency Destabilizes ABCA1 Expression in Human Fibroblasts: Novel Insights in Pathophysiology of Spinal Muscular Atrophy by Gabanella, Francesca, Onori, Annalisa, Pisani, Cinzia, Fiore, Marco, Ferraguti, Giampiero, Colizza, Andrea, de Vincentiis, Marco, Ceccanti, Marco, Inghilleri, Maurizio, Corbi, Nicoletta, Passananti, Claudio, Di Certo, Maria Grazia

“…The deficiency of survival motor neuron protein (SMN) causes spinal muscular atrophy (SMA), a rare neuromuscular disease that affects different organs. SMN is…”
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The RNA-Binding Protein SMN as a Novel Player in Laryngeal Squamous Cell Carcinoma by Gabanella, Francesca, Colizza, Andrea, Mottola, Maria Chiara, Francati, Silvia, Blaconà, Giovanna, Petrella, Carla, Barbato, Christian, Greco, Antonio, Ralli, Massimo, Fiore, Marco, Corbi, Nicoletta, Ferraguti, Giampiero, Corsi, Alessandro, Minni, Antonio, de Vincentiis, Marco, Passananti, Claudio, Di Certo, Maria Grazia

“…Head and neck squamous cell carcinoma (HNSCC) arises from the mucosal epithelium in the oral cavity, pharynx, sino-nasal region, and larynx. Laryngeal squamous…”
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Alcohol and Head and Neck Cancer: Updates on the Role of Oxidative Stress, Genetic, Epigenetics, Oral Microbiota, Antioxidants, and Alkylating Agents by Ferraguti, Giampiero, Terracina, Sergio, Petrella, Carla, Greco, Antonio, Minni, Antonio, Lucarelli, Marco, Agostinelli, Enzo, Ralli, Massimo, de Vincentiis, Marco, Raponi, Giammarco, Polimeni, Antonella, Ceccanti, Mauro, Caronti, Brunella, Di Certo, Maria Grazia, Barbato, Christian, Mattia, Alessandro, Tarani, Luigi, Fiore, Marco

“…Head and neck cancer (HNC) concerns more than 890,000 patients worldwide annually and is associated with the advanced stage at presentation and heavy outcomes…”
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SMN affects membrane remodelling and anchoring of the protein synthesis machinery by Gabanella, Francesca, Pisani, Cinzia, Borreca, Antonella, Farioli-Vecchioli, Stefano, Ciotti, Maria Teresa, Ingegnere, Tiziano, Onori, Annalisa, Ammassari-Teule, Martine, Corbi, Nicoletta, Canu, Nadia, Monaco, Lucia, Passananti, Claudio, Di Certo, Maria Grazia

“…Disconnection between membrane signalling and actin networks can have catastrophic effects depending on cell size and polarity. The survival motor neuron (SMN)…”
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Serum NGF and BDNF in Long-COVID-19 Adolescents: A Pilot Study by Petrella, Carla, Nenna, Raffaella, Petrarca, Laura, Tarani, Francesca, Paparella, Roberto, Mancino, Enrica, Di Mattia, Greta, Conti, Maria Giulia, Matera, Luigi, Bonci, Enea, Ceci, Flavio Maria, Ferraguti, Giampiero, Gabanella, Francesca, Barbato, Christian, Di Certo, Maria Grazia, Cavalcanti, Luca, Minni, Antonio, Midulla, Fabio, Tarani, Luigi, Fiore, Marco

“…COVID-19 (COronaVIrus Disease 19) is an infectious disease also known as an acute respiratory syndrome caused by the SARS-CoV-2. Although in children and…”
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Impact of N-tau on adult hippocampal neurogenesis, anxiety, and memory by Pristerà, Andrea, Saraulli, Daniele, Farioli-Vecchioli, Stefano, Strimpakos, Georgios, Costanzi, Marco, di Certo, Maria Grazia, Cannas, Sara, Ciotti, Maria Teresa, Tirone, Felice, Mattei, Elisabetta, Cestari, Vincenzo, Canu, Nadia

“…Abstract Different pathological tau species are involved in memory loss in Alzheimer's disease, the most common cause of dementia among older people. However,…”
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Oxidative Stress in Transthyretin-Mediated Amyloidosis: An Exploratory Study by Fiore, Marco, Cambieri, Chiara, Libonati, Laura, Moret, Federica, D'Andrea, Edoardo, Di Certo, Maria Grazia, Passananti, Claudio, Gabanella, Francesca, Corbi, Nicoletta, Garibaldi, Matteo, Chimenti, Cristina, Alfarano, Maria, Ferraguti, Giampiero, Francati, Silvia, Inghilleri, Maurizio, Ceccanti, Marco

“…Transthyretin-mediated amyloidosis (ATTR) is a systemic disease with protein precipitation in many tissues, mainly the peripheral nerve and heart. Both genetic…”
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Early Routine Biomarkers of SARS-CoV-2 Morbidity and Mortality: Outcomes from an Emergency Section by Ceci, Flavio Maria, Fiore, Marco, Gavaruzzi, Francesca, Angeloni, Antonio, Lucarelli, Marco, Scagnolari, Carolina, Bonci, Enea, Gabanella, Francesca, Di Certo, Maria Grazia, Barbato, Christian, Petrella, Carla, Greco, Antonio, Vincentiis, Marco De, Ralli, Massimo, Passananti, Claudio, Poscia, Roberto, Minni, Antonio, Ceccanti, Mauro, Tarani, Luigi, Ferraguti, Giampiero

“…COVID-19 is a severe acute respiratory disease caused by SARS-CoV-2, a virus belonging to the Coronaviridae family. This disease has spread rapidly around the…”
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Fine-Tuning of mTOR mRNA and Nucleolin Complexes by SMN by Gabanella, Francesca, Barbato, Christian, Fiore, Marco, Petrella, Carla, de Vincentiis, Marco, Greco, Antonio, Minni, Antonio, Corbi, Nicoletta, Passananti, Claudio, Di Certo, Maria Grazia

“…Increasing evidence points to the Survival Motor Neuron (SMN) protein as a key determinant of translation pathway. Besides its role in RNA processing and…”
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The eEF1γ subunit contacts RNA polymerase II and binds vimentin promoter region by Corbi, Nicoletta, Batassa, Enrico Maria, Pisani, Cinzia, Onori, Annalisa, Di Certo, Maria Grazia, Strimpakos, Georgios, Fanciulli, Maurizio, Mattei, Elisabetta, Passananti, Claudio

“…Here, we show that the eukaryotic translation elongation factor 1 gamma (eEF1γ) physically interacts with the RNA polymerase II (pol II) core subunit 3 (RPB3),…”
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The artificial gene Jazz, a transcriptional regulator of utrophin, corrects the dystrophic pathology in mdx mice by Di Certo, Maria Grazia, Corbi, Nicoletta, Strimpakos, Georgios, Onori, Annalisa, Luvisetto, Siro, Severini, Cinzia, Guglielmotti, Angelo, Batassa, Enrico Maria, Pisani, Cinzia, Floridi, Aristide, Benassi, Barbara, Fanciulli, Maurizio, Magrelli, Armando, Mattei, Elisabetta, Passananti, Claudio

“…The absence of the cytoskeletal protein dystrophin results in Duchenne muscular dystrophy (DMD). The utrophin protein is the best candidate for dystrophin…”
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Utrophin up-regulation by an artificial transcription factor in transgenic mice by Mattei, Elisabetta, Corbi, Nicoletta, Di Certo, Maria Grazia, Strimpakos, Georgios, Severini, Cinzia, Onori, Annalisa, Desantis, Agata, Libri, Valentina, Buontempo, Serena, Floridi, Aristide, Fanciulli, Maurizio, Baban, Dilair, Davies, Kay E, Passananti, Claudio

“…Duchenne Muscular Dystrophy (DMD) is a severe muscle degenerative disease, due to absence of dystrophin. There is currently no effective treatment for DMD. Our…”
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HAX1 is a novel binding partner of Che-1/AATF. Implications in oxidative stress cell response by Pisani, Cinzia, Onori, Annalisa, Gabanella, Francesca, Iezzi, Simona, De Angelis, Roberta, Fanciulli, Maurizio, Colizza, Andrea, de Vincentiis, Marco, Di Certo, Maria Grazia, Passananti, Claudio, Corbi, Nicoletta

“…HAX1 is a multifunctional protein involved in the antagonism of apoptosis in cellular response to oxidative stress. In the present study we identified HAX1 as…”
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Transgenic mice expressing an artificial zinc finger regulator targeting an endogenous gene by Passananti, Claudio, Corbi, Nicoletta, Onori, Annalisa, Di Certo, Maria Grazia, Mattei, Elisabetta

“…Zinc finger (ZF) proteins belonging to the Cys2-His2 class provide a simple and versatile framework to design novel artificial transcription factors (ATFs)…”
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Post-COVID-19 Hyposmia Does Not Exhibit Main Neurodegeneration Markers in the Olfactory Pathway by Schirinzi, Tommaso, Maftei, Daniela, Maurizi, Riccardo, Albanese, Maria, Simonetta, Clara, Bovenzi, Roberta, Bissacco, Jacopo, Mascioli, Davide, Boffa, Laura, Di Certo, Maria Grazia, Gabanella, Francesca, Francavilla, Beatrice, Di Girolamo, Stefano, Mercuri, Nicola Biagio, Passali, Francesco Maria, Lattanzi, Roberta, Severini, Cinzia

“…The biological substrate of persistent post-COVID-19 hyposmia is still unclear. However, as many neurodegenerative diseases present with smell impairment at…”
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