Search Results - "Di Caro, Giuseppe"

Interleukin-17 Receptor A Signaling in Transformed Enterocytes Promotes Early Colorectal Tumorigenesis by Wang, Kepeng, Kim, Min Kyoung, Di Caro, Giuseppe, Wong, Jerry, Shalapour, Shabnam, Wan, Jun, Zhang, Wei, Zhong, Zhenyu, Sanchez-Lopez, Elsa, Wu, Li-Wha, Taniguchi, Koji, Feng, Ying, Fearon, Eric, Grivennikov, Sergei I., Karin, Michael

“…Interleukin-17A (IL-17A) is a pro-inflammatory cytokine linked to rapid malignant progression of colorectal cancer (CRC) and therapy resistance. IL-17A exerts…”
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Fructose stimulated de novo lipogenesis is promoted by inflammation by Todoric, Jelena, Di Caro, Giuseppe, Reibe, Saskia, Henstridge, Darren C., Green, Courtney R., Vrbanac, Alison, Ceteci, Fatih, Conche, Claire, McNulty, Reginald, Shalapour, Shabnam, Taniguchi, Koji, Meikle, Peter J., Watrous, Jeramie D., Moranchel, Rafael, Najhawan, Mahan, Jain, Mohit, Liu, Xiao, Kisseleva, Tatiana, Diaz-Meco, Maria T., Moscat, Jorge, Knight, Rob, Greten, Florian R., Lau, Lester F., Metallo, Christian M., Febbraio, Mark A., Karin, Michael

“…Benign hepatosteatosis, affected by lipid uptake, de novo lipogenesis and fatty acid (FA) oxidation, progresses to non-alcoholic steatohepatitis (NASH) on…”
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Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy by Shalapour, Shabnam, Font-Burgada, Joan, Di Caro, Giuseppe, Zhong, Zhenyu, Sanchez-Lopez, Elsa, Dhar, Debanjan, Willimsky, Gerald, Ammirante, Massimo, Strasner, Amy, Hansel, Donna E., Jamieson, Christina, Kane, Christopher J., Klatte, Tobias, Birner, Peter, Kenner, Lukas, Karin, Michael

“…IgA plasmocytes are shown to promote resistance to the immunogenic chemotherapeutic oxaliplatin in prostate cancer mouse models by inhibiting activation of…”
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Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas by Todoric, Jelena, Antonucci, Laura, Di Caro, Giuseppe, Li, Ning, Wu, Xuefeng, Lytle, Nikki K., Dhar, Debanjan, Banerjee, Sourav, Fagman, Johan B., Browne, Cecille D., Umemura, Atsushi, Valasek, Mark A., Kessler, Hannes, Tarin, David, Goggins, Michael, Reya, Tannishtha, Diaz-Meco, Maria, Moscat, Jorge, Karin, Michael

“…Despite expression of oncogenic KRAS, premalignant pancreatic intraepithelial neoplasia 1 (PanIN1) lesions rarely become fully malignant pancreatic ductal…”
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Immune cells: plastic players along colorectal cancer progression by Di Caro, Giuseppe, Marchesi, Federica, Laghi, Luigi, Grizzi, Fabio

“…Inflammatory cells are involved in tumour initiation and progression. In parallel, the adaptive immune response plays a key role in fighting tumour growth and…”
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Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma by Castino, Giovanni Francesco, Cortese, Nina, Capretti, Giovanni, Serio, Simone, Di Caro, Giuseppe, Mineri, Rossana, Magrini, Elena, Grizzi, Fabio, Cappello, Paola, Novelli, Francesco, Spaggiari, Paola, Roncalli, Massimo, Ridolfi, Cristina, Gavazzi, Francesca, Zerbi, Alessandro, Allavena, Paola, Marchesi, Federica

“…B-cell responses are emerging as critical regulators of cancer progression. In this study, we investigated the role of B lymphocytes in the microenvironment of…”
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YAP–IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis by Taniguchi, Koji, Moroishi, Toshiro, de Jong, Petrus R., Krawczyk, Michal, Grebbin, Britta Moyo, Luo, Huiyan, Xu, Rui-hua, Golob-Schwarzl, Nicole, Schweiger, Caroline, Wang, Kepeng, Di Caro, Giuseppe, Feng, Ying, Fearon, Eric R., Raz, Eyal, Kenner, Lukas, Farin, Henner F., Guan, Kun-Liang, Haybaeck, Johannes, Datz, Christian, Zhang, Kang, Karin, Michael

“…Loss of tumor suppressor adenomatous polyposis coli (APC) activates β-catenin to initiate colorectal tumorigenesis. However, β-catenin (CTNNB1) activating…”
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Tumor-associated macrophages and response to 5-fluorouracil adjuvant therapy in stage III colorectal cancer by Malesci, Alberto, Bianchi, Paolo, Celesti, Giuseppe, Basso, Gianluca, Marchesi, Federica, Grizzi, Fabio, Di Caro, Giuseppe, Cavalleri, Tommaso, Rimassa, Lorenza, Palmqvist, Richard, Lugli, Alessandro, Koelzer, Viktor. H., Roncalli, Massimo, Mantovani, Alberto, Ogino, Shuji, Laghi, Luigi

“…Tumor-associated macrophages (TAMs) play a role in tumor development and progression. We hypothesized that abundance of TAMs might modify efficacy of…”
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Circulating Inflammatory Mediators as Potential Prognostic Markers of Human Colorectal Cancer by Di Caro, Giuseppe, Carvello, Michele, Pesce, Samantha, Erreni, Marco, Marchesi, Federica, Todoric, Jelena, Sacchi, Matteo, Montorsi, Marco, Allavena, Paola, Spinelli, Antonino

“…Cytokines and chemokines in the tumor microenvironment drive metastatic development and their serum levels might mirror the ongoing inflammatory reaction at…”
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A novel liquid biopsy assay for detection of ERBB2 (HER2) amplification in circulating tumor cells (CTCs) by Caro, Giuseppe Di, Lam, Ernest T, Bourdon, David, Blankfard, Martin, Dharajiya, Nilesh, Slade, Megan, Williams, Emily, Zhang, Dong, Wenstrup, Rick, Schwartzberg, Lee

“…Circulating tumor cell (CTC)-based (HER2) assay is a laboratory test developed by Epic Sciences using single-cell genomics to detect (HER2) amplification in…”
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Irrelevance of microsatellite instability in the epidemiology of sporadic pancreatic ductal adenocarcinoma by Laghi, Luigi, Beghelli, Stefania, Spinelli, Antonino, Bianchi, Paolo, Basso, Gianluca, Di Caro, Giuseppe, Brecht, Anna, Celesti, Giuseppe, Turri, Giona, Bersani, Samantha, Schumacher, Guido, Röcken, Christoph, Gräntzdörffer, Ilona, Roncalli, Massimo, Zerbi, Alessandro, Neuhaus, Peter, Bassi, Claudio, Montorsi, Marco, Scarpa, Aldo, Malesci, Alberto

“…Pancreatic cancer risk is increased in Lynch syndrome (LS) patients with mismatch repair gene defects predisposing to colonic and extracolonic cancers with…”
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Correction: Circulating Inflammatory Mediators as Potential Prognostic Markers of Human Colorectal Cancer by Di Caro, Giuseppe, Carvello, Michele, Pesce, Samantha, Erreni, Marco, Marchesi, Federica, Todoric, Jelena, Sacchi, Matteo, Montorsi, Marco, Allavena, Paola, Spinelli, Antonino

“…[This corrects the article DOI: 10.1371/journal.pone.0148186.]…”
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Mast cells are not associated with systemic insulin resistance by Einwallner, Elisa, Kiefer, Florian W., Di Caro, Giuseppe, Orthofer, Michael, Witzeneder, Nadine, Hörmann, Gregor, Itariu, Bianca, Zeyda, Maximilian, Penninger, Josef M., Stulnig, Thomas M., Esterbauer, Harald, Todoric, Jelena

“…Background Infiltration of white adipose tissue (WAT) by inflammatory cells in obesity is considered to be a key event in the development of insulin…”
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MSH3 Protein Expression and Nodal Status in MLH1-Deficient Colorectal Cancers by LAGHI, Luigi, BIANCHI, Paolo, MALESCI, Alberto, DELCONTE, Gabriele, CELESTI, Giuseppe, DI CARO, Giuseppe, PEDRONI, Monica, CHIARAVALLI, Anna Maria, JUNG, Barbara, CAPELLA, Carlo, DE LEON, Maurizio Ponz

“…Patients with colorectal cancers (CRC) and high microsatellite instability (MSI) have a better outcome than their chromosome-unstable counterpart. Given the…”
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Combined low-FOXP3+ and -CD3+tumor infiltrating lymphocytes: a signature of stage II MSS colorectal cancer at high-risk of recurrence by Di Caro, Giuseppe, Celesti, Giuseppe, Grizzi, Fabio, Bianchi, Paolo, Basso, Gianluca, Marchesi, Federica, Mantovani, Alberto, Malesci, Alberto, Laghi, Luigi

“…BackgroundLow densities of tumor infiltrating lymphocytes (TILs) predict colorectal cancer (CRC) post-surgical recurrence, the likelihood of progression also…”
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Dual prognostic significance of tumour-associated macrophages in human pancreatic adenocarcinoma treated or untreated with chemotherapy by Di Caro, Giuseppe, Cortese, Nina, Castino, Giovanni Francesco, Grizzi, Fabio, Gavazzi, Francesca, Ridolfi, Cristina, Capretti, Giovanni, Mineri, Rossana, Todoric, Jelena, Zerbi, Alessandro, Allavena, Paola, Mantovani, Alberto, Marchesi, Federica

“…Tumour-associated macrophages (TAMs) play key roles in tumour progression. Recent evidence suggests that TAMs critically modulate the efficacy of anticancer…”
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Occurrence of Tertiary Lymphoid Tissue Is Associated with T-Cell Infiltration and Predicts Better Prognosis in Early-Stage Colorectal Cancers by DI CARO, Giuseppe, BERGOMAS, Francesca, GRIZZI, Fabio, DONI, Andrea, BIANCHI, Paolo, MALESCI, Alberto, LAGHI, Luigi, ALLAVENA, Paola, MANTOVANI, Alberto, MARCHESIL, Federica

“…Tumor-infiltrating T lymphocytes (TIL) play a key role in the clinical outcome of human colorectal cancer; however, the dynamics of their recruitment along…”
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Occurrence and significance of tumor‐associated neutrophils in patients with colorectal cancer by Galdiero, Maria Rosaria, Bianchi, Paolo, Grizzi, Fabio, Di Caro, Giuseppe, Basso, Gianluca, Ponzetta, Andrea, Bonavita, Eduardo, Barbagallo, Marialuisa, Tartari, Silvia, Polentarutti, Nadia, Malesci, Alberto, Marone, Gianni, Roncalli, Massimo, Laghi, Luigi, Garlanda, Cecilia, Mantovani, Alberto, Jaillon, Sébastien

“…Inflammatory cells are an essential component of the tumor microenvironment. Neutrophils have emerged as important players in the orchestration and effector…”
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Liquid biopsy identification of ERBB2 amplified and HER2 expressing metastatic breast cancer: Comparison and combination of cell and cell-free platforms by Di Caro, Giuseppe, Lam, Ernest, Bourdon, David, Singer, Tatjana, Horne, Kandra, Slade, Megan, Wenstrup, Rick, Schwartzberg, Lee S.

“…3061 Background: Liquid biopsies are a non-invasive diagnostic approach for detecting circulating tumor cells (CTCs) or circulating tumor DNA (ctDNA) that may…”
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Demonstration of the value of liquid biopsy to identify metastatic breast cancer: Comparison and combination of cell and cell-free platforms by Di Caro, Giuseppe, Bourdon, David, Byun, Jiyun, Singer, Tatjana, Anderson, Amanda, Tubbs, Alisa, Blankfard, Martin, Wenstrup, Rick

“…e13004 Background: Liquid biopsy analysis detecting circulating tumor cells (CTC) or circulating tumor DNA (ctDNA) is a non-invasive approach that may provide…”
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