Search Results - "Di Blasio, Anna"

Methylation of ELOVL2 gene as a new epigenetic marker of age by Garagnani, Paolo, Bacalini, Maria G., Pirazzini, Chiara, Gori, Davide, Giuliani, Cristina, Mari, Daniela, Di Blasio, Anna M., Gentilini, Davide, Vitale, Giovanni, Collino, Sebastiano, Rezzi, Serge, Castellani, Gastone, Capri, Miriam, Salvioli, Stefano, Franceschi, Claudio

“…Summary The discovery of biomarkers able to predict biological age of individuals is a crucial goal in aging research. Recently, researchers' attention has…”
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NGS analysis in Marfan syndrome spectrum: Combination of rare and common genetic variants to improve genotype-phenotype correlation analysis by Gentilini, Davide, Oliveri, Antonino, Fazia, Teresa, Pini, Alessandro, Marelli, Susan, Bernardinelli, Luisa, Di Blasio, Anna Maria

“…The diagnosis of Marfan spectrum includes a large number of clinical criteria. Although the identification of pathogenic variants contributes to the diagnostic…”
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Differences in visceral fat and fat bacterial colonization between ulcerative colitis and Crohn's disease. An in vivo and in vitro study by Zulian, Alessandra, Cancello, Raffaella, Ruocco, Chiara, Gentilini, Davide, Di Blasio, Anna Maria, Danelli, Piergiorgio, Micheletto, Giancarlo, Cesana, Elisabetta, Invitti, Cecilia

“…Crohn's disease (CD) is notably characterized by the expansion of visceral fat with small adipocytes expressing a high proportion of anti-inflammatory genes…”
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An overview of the genetic structure within the Italian population from genome-wide data by Di Gaetano, Cornelia, Voglino, Floriana, Guarrera, Simonetta, Fiorito, Giovanni, Rosa, Fabio, Di Blasio, Anna Maria, Manzini, Paola, Dianzani, Irma, Betti, Marta, Cusi, Daniele, Frau, Francesca, Barlassina, Cristina, Mirabelli, Dario, Magnani, Corrado, Glorioso, Nicola, Bonassi, Stefano, Piazza, Alberto, Matullo, Giuseppe

“…In spite of the common belief of Europe as reasonably homogeneous at genetic level, advances in high-throughput genotyping technology have resolved several…”
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Epigenetic patterns, accelerated biological aging, and enhanced epigenetic drift detected 6 months following COVID-19 infection: insights from a genome-wide DNA methylation study by Luciano, Calzari, Fernando, Dragani Davide, Lucia, Zanotti, Elvira, Inglese, Romano, Danesi, Rebecca, Cavagnola, Alberto, Brusati, Francesco, Ranucci, Maria, Di Blasio Anna, Luca, Persani, Irene, Campi, Sara, De Martino, Antonella, Farsetti, Veronica, Barbi, Michela, Gottardi Zamperla, Nicole, Baldrighi Giulia, Carlo, Gaetano, Gianfranco, Parati, Davide, Gentilini

“…The epigenetic status of patients 6-month post-COVID-19 infection remains largely unexplored. The existence of long-COVID, or post-acute sequelae of SARS-CoV-2…”
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Altered Lipid Moieties and Carbonyls in a Wistar Rat Dietary Model of Subclinical Fatty Liver: Potential Sex-Specific Biomarkers of Early Fatty Liver Disease? by Martín-Grau, María, Pardo-Tendero, Mercedes, Casanova, Pilar, Dromant, Mar, Marrachelli, Vannina G, Morales, Jose Manuel, Borrás, Consuelo, Pisoni, Serena, Maestrini, Sabrina, Di Blasio, Anna M, Monleon, Daniel

“…Non-alcoholic fatty liver disease (NAFLD) is a condition in which excess fat builds up in the liver. To date, there is a lack of knowledge about the subtype of…”
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Sex Dimorphism in the Metabolome of Metabolic Syndrome in Morbidly Obese Individuals by Pisoni, Serena, Marrachelli, Vannina G, Morales, Jose M, Maestrini, Sabrina, Di Blasio, Anna M, Monleón, Daniel

“…Adult morbid obesity is defined as abnormal or excessive fat accumulation, mostly resulting from a long-term unhealthy lifestyle. Between 10% and 30% of people…”
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Accelerated epigenetic aging in Down syndrome by Horvath, Steve, Garagnani, Paolo, Bacalini, Maria Giulia, Pirazzini, Chiara, Salvioli, Stefano, Gentilini, Davide, Di Blasio, Anna Maria, Giuliani, Cristina, Tung, Spencer, Vinters, Harry V., Franceschi, Claudio

“…Summary Down Syndrome (DS) entails an increased risk of many chronic diseases that are typically associated with older age. The clinical manifestations of…”
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One-year Mediterranean diet promotes epigenetic rejuvenation with country- and sex-specific effects: a pilot study from the NU-AGE project by Gensous, Noémie, Garagnani, Paolo, Santoro, Aurelia, Giuliani, Cristina, Ostan, Rita, Fabbri, Cristina, Milazzo, Maddalena, Gentilini, Davide, di Blasio, Anna Maria, Pietruszka, Barbara, Madej, Dawid, Bialecka-Debek, Agata, Brzozowska, Anna, Franceschi, Claudio, Bacalini, Maria Giulia

“…Mediterranean diet has been proposed to promote healthy aging, but its effects on aging biomarkers have been poorly investigated. We evaluated the impact of a…”
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Annexin A5 in treated hypertensive patients and its association with target organ damage by Maloberti, Alessandro, Meani, Paolo, Vallerio, Paola, Varrenti, Marisa, Casadei, Francesca, Musca, Francesco, Facchetti, Rita, Di Blasio, Anna M, Ravassa, Susanna, Mancia, Giuseppe, Giannattasio, Cristina

“…OBJECTIVE:Annexin A5 (AnxA5) has been previously linked to the presence of carotid and cardiac target organ damage (TOD) in the context of heart failure and…”
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Episodic ataxia and SCA6 within the same family due to the D302N CACNA1A gene mutation by Pradotto, Luca, MD, PhD, Mencarelli, Monica, Bigoni, Matteo, MD, Milesi, Alessandra, Di Blasio, Anna, MD, Mauro, Alessandro, MD

“…Abstract Several dominant mutations of CACNA1A gene were associated with at least three different allelic disorders: spino-cerebellar ataxia type 6 (SCA6),…”
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Variant on chromosome 9p is associated with left ventricular mass: results from two cohorts of essential hypertensive individuals by Menni, Cristina, Boffi, Lucia, Cesana, Francesca, Viviani Anselmi, Chiara, Nava, Stefano, Bertola, Francesca, Blasio, Anna M Di, Roncarati, Roberta, Trimarco, Valentina, Marino, Marina, Trimarco, Bruno, Grassi, Guido, Giannattasio, Cristina, Mancia, Giuseppe

“…OBJECTIVES:It is well known that among hypertensive patients, an increased left ventricular mass (LVM) is a powerful predictor of cardiovascular morbidity and…”
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The genomic landscape of Nepalese Tibeto-Burmans reveals new insights into the recent peopling of Southern Himalayas by Gnecchi-Ruscone, Guido A., Jeong, Choongwon, De Fanti, Sara, Sarno, Stefania, Trancucci, Michela, Gentilini, Davide, Di Blasio, Anna M., Sherpa, Mingma G., Sherpa, Phurba T., Marinelli, Giorgio, Di Marcello, Marco, Natali, Luca, Peluzzi, Davide, Pettener, Davide, Di Rienzo, Anna, Luiselli, Donata, Sazzini, Marco

“…While much research attention has focused on demographic processes that enabled human diffusion on the Tibetan plateau, little is known about more recent…”
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Synergistic activity of everolimus and 5‐aza‐2′‐deoxycytidine in medullary thyroid carcinoma cell lines by Vitale, Giovanni, Dicitore, Alessandra, Pepe, Daniele, Gentilini, Davide, Grassi, Elisa S., Borghi, Maria O., Gelmini, Giulia, Cantone, Maria C., Gaudenzi, Germano, Misso, Gabriella, Di Blasio, Anna M., Hofland, Leo J., Caraglia, Michele, Persani, Luca

“…Medullary thyroid cancer (MTC) is a tumor highly resistant to chemo‐ and radiotherapy. Drug resistance can be induced by epigenetic changes such as aberrant…”
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Gonadotropin‐releasing hormone analogues added to adjuvant chemotherapy protect ovarian function and improve clinical outcomes in young women with early breast carcinoma by Recchia, Francesco, Saggio, Gaetano, Amiconi, Giovanna, Blasio, Anna Di, Cesta, Alisia, Candeloro, Giampiero, Rea, Silvio

“…BACKGROUND The objective of the current study was a retrospective evaluation of 100 consecutive premenopausal women with high‐risk, early breast carcinoma who…”
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Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension by Padmanabhan, Sandosh, Melander, Olle, Johnson, Toby, Di Blasio, Anna Maria, Lee, Wai K, Gentilini, Davide, Hastie, Claire E, Menni, Cristina, Monti, Maria Cristina, Delles, Christian, Laing, Stewart, Corso, Barbara, Navis, Gerjan, Kwakernaak, Arjan J, van der Harst, Pim, Bochud, Murielle, Maillard, Marc, Burnier, Michel, Hedner, Thomas, Kjeldsen, Sverre, Wahlstrand, Björn, Sjögren, Marketa, Fava, Cristiano, Montagnana, Martina, Danese, Elisa, Torffvit, Ole, Hedblad, Bo, Snieder, Harold, Connell, John M C, Brown, Morris, Samani, Nilesh J, Farrall, Martin, Cesana, Giancarlo, Mancia, Giuseppe, Signorini, Stefano, Grassi, Guido, Eyheramendy, Susana, Wichmann, H Erich, Laan, Maris, Strachan, David P, Sever, Peter, Shields, Denis Colm, Stanton, Alice, Vollenweider, Peter, Teumer, Alexander, Völzke, Henry, Rettig, Rainer, Newton-Cheh, Christopher, Arora, Pankaj, Zhang, Feng, Soranzo, Nicole, Spector, Timothy D, Lucas, Gavin, Kathiresan, Sekar, Siscovick, David S, Luan, Jian'an, Loos, Ruth J F, Wareham, Nicholas J, Penninx, Brenda W, Nolte, Ilja M, McBride, Martin, Miller, William H, Nicklin, Stuart A, Baker, Andrew H, Graham, Delyth, McDonald, Robert A, Pell, Jill P, Sattar, Naveed, Welsh, Paul, Munroe, Patricia, Caulfield, Mark J, Zanchetti, Alberto, Dominiczak, Anna F

“…Hypertension is a heritable and major contributor to the global burden of disease. The sum of rare and common genetic variants robustly identified so far…”
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Altered modulation of lamin A/C‐HDAC2 interaction and p21 expression during oxidative stress response in HGPS by Mattioli, Elisabetta, Andrenacci, Davide, Garofalo, Cecilia, Prencipe, Sabino, Scotlandi, Katia, Remondini, Daniel, Gentilini, Davide, Di Blasio, Anna Maria, Valente, Sergio, Scarano, Emanuela, Cicchilitti, Lucia, Piaggio, Giulia, Mai, Antonello, Lattanzi, Giovanna

“…Defects in stress response are main determinants of cellular senescence and organism aging. In fibroblasts from patients affected by Hutchinson–Gilford…”
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Role of epigenetics in the clinical evolution of COVID-19 disease. Epigenome-wide association study identifies markers of severe outcome by Calzari, Luciano, Zanotti, Lucia, Inglese, Elvira, Scaglione, Francesco, Cavagnola, Rebecca, Ranucci, Francesco, Di Blasio, Anna Maria, Stefanini, Giulio, Carlo, Gaetano, Parati, Gianfranco, Gentilini, Davide

“…COVID-19 has a wide spectrum of clinical manifestations and given its impact on morbidity and mortality, there is an unmet medical need to discover endogenous…”
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Epigenome Wide Association and Stochastic Epigenetic Mutation Analysis on Cord Blood of Preterm Birth by Spada, Elena, Calzari, Luciano, Corsaro, Luigi, Fazia, Teresa, Mencarelli, Monica, Di Blasio, Anna Maria, Bernardinelli, Luisa, Zangheri, Giulia, Vignali, Michele, Gentilini, Davide

“…Preterm birth (PTB) can be defined as the endpoint of a complex process that could be influenced by maternal and environmental factors. Epigenetics recently…”
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Epigenome-wide association study in hepatocellular carcinoma: Identification of stochastic epigenetic mutations through an innovative statistical approach by Gentilini, Davide, Scala, Stefania, Gaudenzi, Germano, Garagnani, Paolo, Capri, Miriam, Cescon, Matteo, Grazi, Gian Luca, Bacalini, Maria Giulia, Pisoni, Serena, Dicitore, Alessandra, Circelli, Luisa, Santagata, Sara, Izzo, Francesco, Di Blasio, Anna Maria, Persani, Luca, Franceschi, Claudio, Vitale, Giovanni

“…Hepatocellular carcinoma (HCC) results from accumulation of both genetic and epigenetic alterations. We investigated the genome-wide DNA methylation profile in…”
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