Search Results - "Di Bari, Michele"

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    Cofactor and glycosylation preferences for in vitro prion conversion are predominantly determined by strain conformation by Burke, Cassandra M, Walsh, Daniel J, Mark, Kenneth M K, Deleault, Nathan R, Nishina, Koren A, Agrimi, Umberto, Di Bari, Michele A, Supattapone, Surachai

    Published in PLoS pathogens (15-04-2020)
    “…Prion diseases are caused by the misfolding of a host-encoded glycoprotein, PrPC, into a pathogenic conformer, PrPSc. Infectious prions can exist as different…”
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    Full restoration of specific infectivity and strain properties from pure mammalian prion protein by Burke, Cassandra M, Walsh, Daniel J, Steele, Alexander D, Agrimi, Umberto, Di Bari, Michele Angelo, Watts, Joel C, Supattapone, Surachai

    Published in PLoS pathogens (01-03-2019)
    “…The protein-only hypothesis predicts that infectious mammalian prions are composed solely of PrPSc, a misfolded conformer of the normal prion protein, PrPC…”
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    Prion Disease in Dromedary Camels, Algeria by Babelhadj, Baaissa, Di Bari, Michele Angelo, Pirisinu, Laura, Chiappini, Barbara, Gaouar, Semir Bechir Suheil, Riccardi, Geraldina, Marcon, Stefano, Agrimi, Umberto, Nonno, Romolo, Vaccari, Gabriele

    Published in Emerging infectious diseases (01-06-2018)
    “…Prions cause fatal and transmissible neurodegenerative diseases, including Creutzfeldt-Jakob disease in humans, scrapie in small ruminants, and bovine…”
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    Efficient transmission and characterization of Creutzfeldt-Jakob disease strains in bank voles by Nonno, Romolo, Di Bari, Michele A, Cardone, Franco, Vaccari, Gabriele, Fazzi, Paola, Dell'Omo, Giacomo, Cartoni, Claudia, Ingrosso, Loredana, Boyle, Aileen, Galeno, Roberta, Sbriccoli, Marco, Lipp, Hans-Peter, Bruce, Moira, Pocchiari, Maurizio, Agrimi, Umberto

    Published in PLoS pathogens (01-02-2006)
    “…Transmission of prions between species is limited by the "species barrier," which hampers a full characterization of human prion strains in the mouse model. We…”
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    Gerstmann-Sträussler-Scheinker disease subtypes efficiently transmit in bank voles as genuine prion diseases by Pirisinu, Laura, Di Bari, Michele A., D’Agostino, Claudia, Marcon, Stefano, Riccardi, Geraldina, Poleggi, Anna, Cohen, Mark L., Appleby, Brian S., Gambetti, Pierluigi, Ghetti, Bernardino, Agrimi, Umberto, Nonno, Romolo

    Published in Scientific reports (04-02-2016)
    “…Gerstmann-Sträussler-Scheinker disease (GSS) is an inherited neurodegenerative disorder associated with mutations in the prion protein gene and accumulation of…”
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    Prion disease tempo determined by host-dependent substrate reduction by Mays, Charles E, Kim, Chae, Haldiman, Tracy, van der Merwe, Jacques, Lau, Agnes, Yang, Jing, Grams, Jennifer, Di Bari, Michele A, Nonno, Romolo, Telling, Glenn C, Kong, Qingzhong, Langeveld, Jan, McKenzie, Debbie, Westaway, David, Safar, Jiri G

    Published in The Journal of clinical investigation (01-02-2014)
    “…The symptoms of prion infection can take years or decades to manifest following the initial exposure. Molecular markers of prion disease include accumulation…”
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    Accumulation and aberrant composition of cholesteryl esters in Scrapie-infected N2a cells and C57BL/6 mouse brains by Vascellari, Sarah, Banni, Sebastiano, Vacca, Claudia, Vetrugno, Vito, Cardone, Franco, Di Bari, Michele A, La Colla, Paolo, Pani, Alessandra

    Published in Lipids in health and disease (04-08-2011)
    “…Cholesterol changes have been described in prion-cell models and in experimental rodent scrapie; yet, the pattern of this association is still controversial…”
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    Molecular discrimination of sheep bovine spongiform encephalopathy from scrapie by Pirisinu, Laura, Migliore, Sergio, Di Bari, Michele Angelo, Esposito, Elena, Baron, Thierry, D'Agostino, Claudia, De Grossi, Luigi, Vaccari, Gabriele, Agrimi, Umberto, Nonno, Romolo

    Published in Emerging infectious diseases (01-04-2011)
    “…Sheep CH1641-like transmissible spongiform encephalopathy isolates have shown molecular similarities to bovine spongiform encephalopathy (BSE) isolates. We…”
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    Transmissibility of Gerstmann-Sträussler-Scheinker syndrome in rodent models: New insights into the molecular underpinnings of prion infectivity by Nonno, Romolo, Angelo Di Bari, Michele, Agrimi, Umberto, Pirisinu, Laura

    Published in Prion (01-11-2016)
    “…Prion diseases, or transmissible spongiform encephalopathies, have revealed the bewildering phenomenon of transmissibility in neurodegenerative diseases…”
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    Biochemical characterization of prion strains in bank voles by Pirisinu, Laura, Marcon, Stefano, Di Bari, Michele Angelo, D'Agostino, Claudia, Agrimi, Umberto, Nonno, Romolo

    Published in Pathogens (Basel) (02-07-2013)
    “…Prions exist as different strains exhibiting distinct disease phenotypes. Currently, the identification of prion strains is still based on biological strain…”
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